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Immunological Tolerance Monitoring in Solid Organ Transplantation

Moon JY, Lee SH

In organ transplantation, achieving an operational tolerance is the ultimate goal. However, inducing this tolerance with a minimal dose of anti-rejection drugs can only be safely achieved when guided by...
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Successful Sirolimus Treatment of Kaposi's Sarcoma in Multiple Pulmonary Nodules after Kidney Transplantation

Kim SY, Lee HJ, Chung YJ, Sheen S, Lee JH, Oh CK

Kaposi's sarcoma is one of the most serious complications associated with immune suppression treatment after kidney transplantation. Because it usually manifestations as skin lesions or lymphadenopathies, its clinical suspicion and...
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Changes in Serum Cytokine Profile after AEB071 (Sotrastaurin) or Tacrolimus versus Their Combinations in Rat Heterotopic Cardiac Allografts

Joo DJ, Fang YH, Huh KH, Kim MS, Suh H, Kim YS

BACKGROUND: AEB071, an orally available PKC inhibitor, prevents organ rejection after transplantation in rodents and man. Furthermore, pro-inflammatory cytokines and inflammatory processes are important mediators of transplanted organ rejection. We...
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Multicenter Clinical Investigation for the Safety and Efficacy of Advagraf(R) (Extended Release Tacrolimus) versus Prograf(R) (Tacrolimus) in De Novo Kidney Recipients after 1 Month of Transplantation: Preliminary Results

Lee JH, Huh KH, Lee JS, Oh CK, Cho HR, Kim YS

BACKGROUND: Compliance from kidney transplant recipients might improve with less frequent doses of immunosuppressant drugs. We describe the development of an extended-release formulation of tacrolimus that enables taking the drug...
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A Single Center Experience of ABO Incompatible Kidney Transplantation

Chang CL, Jeong JH, Kim JP, Lee DR, Kong JM, Kim BC

BACKGROUND: Kidney transplantation (KT) is the optimal treatment for end stage renal disease. However, the relative shortage of organs for transplantation (from human leukocyte antigen- or ABO incompatible [ABOi] living...
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Successful Sirolimus Treatment of Multiple Visceral Kaposi's Sarcoma in a Renal Allograft Patient

Kim MH, Kim MS, Cha YJ, Park KS, Kim BS, Lee S

The use of immunosuppressant's increases the risk of developing malignancies in renal allograft patients. One of the most important malignancies, Kaposi's sarcoma, can cause mortality and graft failure among renal...
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Analysis of Biliary Stricture after ABO Incompatible Adult Living Donor Liver Transplantation

Yoon YI, Song GW, Lee SG, Hwang S, Ahn CS, Kim KH, Moon DB, Ha TY, Jung DH, Park GC, Namgung JM, Park YH, Park CS, Park HW, Kang SH, Jung BH

BACKGROUND: Despite recent improvements in survival outcome after ABO incompatible (ABOi) adult living donor liver transplantation (ALDLT), concerns about the incidence of biliary stricture (BS) still exist. However, reports on...
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Liver Transplantation for Hepatitis C Virus-Related Liver Disease in Korea

Lee HW, Lee KW, Kim BW, Song GW, Han YS, Kwon CH, Kim SH, Choi GH, Choi JY

BACKGROUND: A management protocol for hepatitis C virus (HCV) after liver transplantation (LT) has not been established in Korea. We therefore investigated HCV transplant protocols and post-transplant results from liver...
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Acute Renal Failure in a Renal Allograft Recipient Caused by a Post-Biopsy Renal Arteriovenous Fistula with Transplant Renal Artery Stenosis

Lee JH, Lee HR, Choi SH, Jung P, Oh JS, Kim SM, Sin YH, Jung YS, Jung GS, Kim JK

Renal biopsy is an essential diagnostic tool for detecting acute and chronic kidney rejection as well as recurrent and de novo nephropathies in renal allograft recipients. However, a well-known complication...
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