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Canditate Gene Approach for the Genetics of Type 2 Diabetes Mellitus

Park JH

  • KMID: 2331686
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):439-441.
No abstract is available.
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Insulin Gene Polymorphisms in non-insulin-dependent Diabetes Mellitus ( NIDDM ) in Korean

Kwon JS, Park SW, Cha BS, Song YD, Ahn CW, Jang KS, Kim SJ, Lim SK, Kim KR, Lee HC, Huh KB

  • KMID: 2331687
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):442-449.
BACKGROUND: Many epidemiologic and family studies indicated stronger influence of genetic factors in NiDDM compared to IDDM, and there has been investigations to identify the susceptibility genes but without definite...
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Simple Diagnostic Method of Diabetic Distal Polyneuropathy in Type 2 Diabetics

Kim CH, Lee KI, Han SG, Heo JH, Lee KJ

  • KMID: 2331701
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):561-567.
BACKGROUND: Early diagnosis of diabetic distal polyneuropathy, a common chronic complication of diabetes mellitus, is important in the management of diabetes mellitus. Michigan Diabetic Neuropathy Score(MDNS) is a good method...
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Prevalence and Risk Factors of Erectile Dysfunction in Diabetic Men by Self-Reported Questionnaires

Lee JH, Oh JY, Hong YS, Sung YA, Kyung NH, Chung WS, Choi EY

  • KMID: 2331698
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):538-545.
BACKGROUND: Erectile dysfunction is the consistent inability to achieve or sustain an erection of suffieient rigidity for sexual intercourse. Erectile dysfunction is an important cause of decreased quality of life...
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A Case of Diabetic Hyporeninemic Hypoaldosteronism Associated with Muscular Symptoms Due to Hyperkalemia

Oh JY, Sung YA, Lee SW, Sim J

  • KMID: 2331702
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):568-573.
Diabetic hyporeninemic hypoaldosteronism is clinically defined syndrome which is characterized by hyperkalemic hyperchloremic metabolic acidosis in patients with diabetic autonomic neuropathy and nephropathy. The major cause of hyporeninemia in diabetes...
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Plasma leptin Concentrations in Korean Type 2 Diabetic Patients

Oh EY, Chung YJ, Choi YH, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

  • KMID: 2331697
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):531-537.
BACKGROUND: Obesity is a well-established risk factor for a number of chronic diseases, including type 2 diabetes mellitus, hypertension, cardiovascular disease, and hyperlipidemia. Leptin, the protein procluct of the ob...
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Combined Measurements of Anti-ICA512 and Anti-GAD Antibodies in Insulin-dependent Diabetes Mellitus and Slowly Progressive Insulin-dependent Diabetes Mellitus in Korea

Kim KA, Ahn KJ, Chung JH, Min YK, Lee MK, Oh PS, Jin DK, Kim BT, Park HJ, Kim KW, Lee MS

  • KMID: 2331692
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):482-490.
BACKGROUND: Type 1 diabetes mellitus is a chronic autoimmune disease in which circulating antibodies to various islet-specific antigens including autoantibodies to glutamic acid decarboxylase (GADAb), antibodies reacting with an islet...
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The Significance of thebeta3 Adrenergic Receptor Gene Polymorphism in Obese Koreans

Kim BJ, Kim SH, Kim DJ, Hahm JR, Kim JS, Ahn KJ, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

  • KMID: 2331688
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):450-456.
BACKGROUND: The b3 adrenergic receptor (b3-AR), expressed mainly in visceral fat of human, is involved in regulation of lipolysis and thermogenesis. The missense mutation of b3-AR gene, resulting in the...
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The Role of Insulin Secretion and Insulin Resistance in the Development of Korean Type 2 Diabetes Mellitus

Chae BN, Lee SK, Hong EG, Chung YS, Lee KW, Kim HM

  • KMID: 2331693
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):491-503.
BACKGROUND: Impaired insulin secretinn, peripheral insulin resistance, a disproportionately elevated rate of hepatic glucose production and influence of inherited or enviromental factors contribute to the pathogenesis of type 2 diabetes...
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Serum Levels of Transforming Growth Factor ( TGF ) -beta1 in Type 2 Diabetic Patients

Kim NH, Oh JH, Kim YH, Park IB, Kim SJ, Baik SH, Choi DS

  • KMID: 2331696
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):522-530.
BACKGROUND: Transforming growth factor(TGF)-Bl is a potent inducer of extracellular matrix production and of fibrogenesis and has been associated wnh the occurrence of diabetic complications. Our aim was to determine...
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Association between FABP2 Gene Polymorphism and Energy Metabolism in Normal Korean

Yun SK, Kim CH, Kim YS, Byun DW, Suh KI, Yoo MH, Kim GB

  • KMID: 2331689
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):457-466.
BACKGROUND: The human intestinal fatty acid binding protein (FABP2) locus has been proprosed to be a major candidate gene in determining insulin resistance. It has been hypothesized that alanine to...
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Estimation of Cut-off Point of Fasting Blood Glucose Predicting Pancreaticbeta-cell Decompensation During Oral Glucose Tolerance Test

Lee MD, Kim HS, Kim YU, Shin YG, Song CH, Won YJ, Chung CH

  • KMID: 2331695
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):513-521.
BACKGROUND: The secretory dysfunction of pancreatic B-cell is one of the important in the pathogenesis of NIDDM. And the conversion from IGT to DM is developed by the exhaustion and...
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Relationship between Circadian Mean Blood Pressure ( MBP ) Rhythm and Microvascular Complications in Normotensive NIDDM Patients

Kim H, Shim SC, Shim DJ, Lee HM, Choi YS, Kang JH, Kim BI, Lee SJ, Kim YL, Cho YK

  • KMID: 2331700
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):552-560.
BACKGROUND: Thanks to ambulatory 24-h blood pressure monitoring device, it became possible to investigate circadian pressure rhythm under variable physiologic and pathologic conditions. Moreover, ambulatory 24-h blood pressure has allowed...
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Development of Proinsulin-secreting Non-endocrine Cell

Yoon DJ, Kim SH, Kim JW, Kim YK, Song YD, Ahn YH

  • KMID: 2331690
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):467-474.
BACKGROUND: Recently, the advent of genetic engineering technics enabled. us to transfer foreign genes of interests into various cells and establish an "artificial b-cells" capable of secreting insulin in response...
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HbA1c Concentration of Elderly Diabetic Patients with the Hypoglycemic Shock who were Admitted via Emergency Room

Park JC, Yoo HJ, Yim HS, Kim YT, Jin DK, Kim HK, Kim DM, Yoo JM, Ihm SH, Choi MG, Park SW

  • KMID: 2331699
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):546-551.
BACKGROUND: Mild degree of hypoglycemia is not unusual during drug therapy in elderly diabetic patients. However it is very difficult that the precise incidence of hypoglycemia is measured in elderly...
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The Effects of Metformin Given into the Brain on Food Intake and a Expressions of Hypothalamic Neurotransmitters in the Rats

Kim ES, Kim JY, Kim SW, Park JY, Lee KU, Hong SK

  • KMID: 2331691
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):475-481.
BACKGROUND: Metformin, a biguanide agent, is an oral hypoglycemic agent frequently prescribed to non-insulin-dependent diabetic patients. In adclition to the glucose lowering effect, it is known to suppress fol intake,...
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Insulin Resistance and Related Factors in the Healthy Young Men

Park SW, Chung YS, Yun YS, Cha BS, Song YD, Lee HC, Huh KB

  • KMID: 2331694
  • J Korean Diabetes Assoc.
  • 1998 Dec;22(4):504-512.
BACKGROUND: Resistance to insulin-stimulated glucose uptake is present in the majority of patients with obesity, glucose intolerance, hypertension, dyslipidemia, and coronary artery disease. It is known that values for insulin-stimulated...
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