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Lack of Effectiveness of Glomerular Hyperfiltration on Development of Microalbuminuria in Type 2 Diabetic Patients: five Year Follow-up Study

Kim ES, Kim SW, Kim JY, Park JY, Hong SK, Lee KU

  • KMID: 2331721
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):155-161.
BACKGROUND: Glomerular hyperfiltration (GHF) is found in 30-40% of patients with type 1 diabetes at the onset of the disease. Several lines of evidence suggest that this might be responsible...
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Self-Care and Related Factors in Patients with Diabetes

Chun JH, Jung SB, Sohn HS

  • KMID: 2331725
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):193-206.
BACKGROUND: In patients with diabetes, self-care might be important for the prevention of complications and the improvement of quality of life. METHODS: To investigate the factors related to self-care in...
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A Case of Insulin Dependent Diabetes Mellitus with MELAS Syndrome Associated with a Mutation of Mitochondrial DNA

Choi MH, Rhim HM, Oh KW, Kang MI, Cha BY, Lee KW, Son HY, Kang SK, Lee HC, Huh KB

  • KMID: 2331726
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):207-214.
Mitochondrial mutations are associated with a wide range of disorders (Kearns-Sayre and chronic progressive external ophthalmoplegia syndromes, Myoclonic epilepsy and ragged-red fibre disease, Mitoehondrial encephalomyopathy, lactic acidosis, and stroke-like episodes,...
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Plasma Proinsulin Levels among the Control, Impaired Glucose Tolerance and Type 2 Diabetes Mellitus during Oral Glucose Tolerance Test

Lee MD, Kim YU, Kim HS, Shin YG, Chung CH

  • KMID: 2331720
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):147-154.
BACKGROUND: Increased secretion of proinsulin has been associated with beta-cell dysfunction. Hyper-proinsulinemia is suggested to be a predictor for the progression of IGT to type 2 DM. In this study,...
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The Effect of Cyclosporine on Insulin Sensitivity in Streptozotocin Induced Diabetic Rats

Kang JS, Kim DS, Lee CB, Park YS, Choi WH, Kim TW, Kim MH

  • KMID: 2331719
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):142-146.
BACKGROUND: Cyclosporine (CsA), being used as a immunosuppressant is known to have deleterious effects on the liver and kidney, but the harmful effect on glucose tolerance has not been clearly...
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The Risk Factors of Diabetic Retinopathy in NIDDM Patients

Seo WT, Song SO, Kim SY, Choi YS, Jang HR, Lee SJ

  • KMID: 2331722
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):162-171.
BACKGROUND: Diabetic retinopathy, which is one of the microvascular complications, has been shown to be related to visual disturbance and blindness. In this report we examined the risk factors for...
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The Relationship between Apolipoprotein E Phenotypes, Serum Lipid Metabolism, and Oxidative Stress in Korean Type 2 Diabetic Patients

Choi SB, Park SM

  • KMID: 2331724
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):182-192.
BACKGROUND:The cause of type 2 diabetes mellitus (DM) is not known, but one of the causes may be the reduction of insulin secretion through the fibrosis formed with amyloid deposits...
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Risk Factors for Peripheral Arterial Disease as Screened by Plethysmography in Patients with NIDDM

Chang HJ, Kim DJ, Choi BJ, Ko YG, Ahn CW, Ryu DR, Yun YS, Han SH, Nam JH, Park SW, Song YD, Lim SK, Kim KR, Shim WH, Lee HC, Huh KB

  • KMID: 2331723
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):172-181.
BACKGROUND: Peripheral arterial disease (PAD) is one of the clinical manifestations of the atherosclerotic disease process. Early onset and rapid progression of PAD in diabetic patients has been well documented....
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Effect of Hyperglycemia on Internalization of Insulin-receptor Complexes in Human Umbilical Vein Endothelial Cells

Song KH, Ahn YB, Han JH, Yoo SJ, Yoon KH, Kang MI, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 2331718
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):131-141.
BACKGROUND: It is well known that hyperglycemia activates protein kinase C (PKC) in vascular endothelial cells. However, the effect of hyperglycemia on internalization and recycling of insulin receptors by insulin...
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Regulation of Guanine Nucleotide Binding Protein Activity in Normal Rat Pancreatic Islet Secretory Granule by Arachidonic Acid and its Metabolites

Sung YA

  • KMID: 2331717
  • J Korean Diabetes Assoc.
  • 1999 Apr;23(2):120-130.
BACKGROUND: Arachidonic acid (AA) generated by the activation of phospholipase A2. and 12hydroxyeicasateraenoic acid (12-HEIE), a lipoxygenase metabolite of AA stimulates glucose induced insulin secretion in pancreatic islets, whereas prostaglandin...
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