- Altered T cell and monocyte subsets in prolonged immune reconstitution inflammatory syndrome related with DRESS (drug reaction with eosinophilia and systemic symptoms)
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Kang SY, Kim J, Ham J, Cho SH, Kang HR, Kim HY
- KMID: 2469855
- Asia Pac Allergy.
- 2020 Jan;10(1):e2.
- doi: 10.5415/apallergy.2020.10.e2
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe cutaneous adverse reaction involving various internal organs. Flare-ups after recovery from the initial presentation of DRESS are caused... -
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- Antiallergic Effect of Hizikia fusiformis in an Ovalbumin-Induced Allergic Rhinitis Mouse Model
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Zhang YL, Shin HJ, Lee JH, Lee J
- KMID: 2447429
- Clin Exp Otorhinolaryngol.
- 2019 May;12(2):196-205.
- doi: 10.21053/ceo.2019.00094
OBJECTIVES: The extract of Hizikia fusiformis is known to exhibit anticancer, antiatopic and antioxidant activities. We aimed to investigate the extract of H. fusiformis on allergic rhinitis inflammation in a... -
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- A Salmonella Typhi ghost induced by the E gene of phage φX174 stimulates dendritic cells and efficiently activates the adaptive immune response
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Won G, Eo SK, Park SY, Hur J, Lee JH
- KMID: 2417569
- J Vet Sci.
- 2018 Jul;19(4):536-542.
- doi: 10.4142/jvs.2018.19.4.536
Previously, we genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost in stimulating the adaptive... -
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- The Role of Thymic Stromal Lymphopoietin (TSLP) in Glomerulonephritis
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Lee KH, Yang JW, Cho JY, Lee JY, Lim EK, Eisenhut M, Jeong DY, Steingroever J, Shin JI
- KMID: 2435350
- Child Kidney Dis.
- 2018 Apr;22(1):17-21.
- doi: 10.3339/jkspn.2018.22.1.17
Thymic stromal lymphopoietin (TSLP) is an interleukin-7-like cytokine that is an important trigger and initiator of many allergic diseases. TSLP promotes a T-helper type 2 (Th2) cytokine response that can... -
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- T-Helper Type 2 Cells Direct Antigen-Induced Eosinophilic Skin Inflammation in Mice
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Kaminuma O, Nishimura , Kitamura N, Saeki M, Hiroi T, Mori A
- KMID: 2428852
- Allergy Asthma Immunol Res.
- 2018 Jan;10(1):77-82.
- doi: 10.4168/aair.2018.10.1.77
Eosinophilic inflammation in combination with immunoglobulin E (IgE) production is a characteristic feature of atopic dermatitis. Although activated T-helper type (Th) 2 cells play critical roles in the local accumulation... -
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- Therapeutic effects of orally administered CJLP55 for atopic dermatitis via the regulation of immune response
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Hyung KE, Kim SJ, Jang YW, Lee DK, Hyun KH, Moon BS, Kim B, Ahn H, Park SY, Sohn UD, Park ES, Hwang KW
- KMID: 2376962
- Korean J Physiol Pharmacol.
- 2017 May;21(3):335-343.
- doi: 10.4196/kjpp.2017.21.3.335
Atopic dermatitis (AD) is an inflammatory skin condition accompanied by symptoms such as edema and hemorrhage. Kimchi is a traditional fermented Korean dish consisting of various probiotics. In this study,... -
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- House Dust Mite-Derived Chitin Enhances Th2 Cell Response to Inhaled Allergens, Mainly via a TNF-α-Dependent Pathway
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Choi JP, Lee SM, Choi HI, Kim MH, Jeon SG, Jang MH, Jee YK, Yang S, Cho YJ, Kim YK
- KMID: 2165920
- Allergy Asthma Immunol Res.
- 2016 Jul;8(4):362-374.
- doi: 10.4168/aair.2016.8.4.362
PURPOSE: Chitin is a potent adjuvant in the development of immune response to inhaled allergens in the airways. According to other studies, chitin is known as multi-faced adjuvants which can... -
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- Roles of RUNX1 and PU.1 in CCR3 Transcription
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Kong SK, Kim BS, Hwang SM, Lee HH, Chung IY
- KMID: 2299791
- Immune Netw.
- 2016 Jun;16(3):176-182.
- doi: 10.4110/in.2016.16.3.176
CCR3 is a chemokine receptor that mediates the accumulation of allergic inflammatory cells, including eosinophils and Th2 cells, at inflamed sites. The regulatory sequence of the CCR3 gene, contains two... -
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- Stem cell therapy in animal models of allergic airway diseases
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Cho KS
- KMID: 2165077
- Allergy Asthma Respir Dis.
- 2016 May;4(3):167-173.
- doi: 10.4168/aard.2016.4.3.167
Allergic airway diseases are characterized by T-helper type 2 (Th2)-skewed eosinophilic inflammation, mucus hypersecretion, and airway hyperresponsiveness. The excessive activation of Th2 cells due to insufficient suppression of regulatory T... -
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- Induction of CD4+ Regulatory and Polarized Effector/helper T Cells by Dendritic Cells
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Lutz MB
- KMID: 2154807
- Immune Netw.
- 2016 Feb;16(1):13-25.
- doi: 10.4110/in.2016.16.1.13
Dendritic cells (DCs) are considered to play major roles during the induction of T cell immune responses as well as the maintenance of T cell tolerance. Naive CD4+ T cells... -
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- Regulation of Th2 Cell Immunity by Dendritic Cells
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Na H, Cho M, Chung Y
- KMID: 2154806
- Immune Netw.
- 2016 Feb;16(1):1-12.
- doi: 10.4110/in.2016.16.1.1
Th2 cell immunity is required for host defense against helminths, but it is detrimental in allergic diseases in humans. Unlike Th1 cell and Th17 cell subsets, the mechanism by which... -
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- T-Helper Cytokine Profiles in Patients with Kawasaki Disease
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Lee SB, Kim YH, Hyun MC, Kim YH, Kim HS, Lee YH
- KMID: 2223791
- Korean Circ J.
- 2015 Nov;45(6):516-521.
- doi: 10.4070/kcj.2015.45.6.516
BACKGROUND AND OBJECTIVES: Kawasaki disease is an acute systemic vasculitis of which pathogenesis suspected is caused by immune dysregulation. The goal of this study is to evaluate the activation pattern... -
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- Effect of Retinoic Acid in a Mouse Model of Allergic Rhinitis
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Son HL, Park HR, Park YJ, Kim SW
- KMID: 2130266
- Allergy Asthma Immunol Res.
- 2015 Nov;7(6):590-598.
- doi: 10.4168/aair.2015.7.6.590
PURPOSE: All-trans retinoic acid (ATRA) modulates immune responses by affecting T cells. Several studies have revealed that allergic inflammation of the lower airways is negatively associated with the vitamin A... -
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- Toll-Like Receptor Gene Expression during Trichinella spiralis Infection
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Kim S, Park MK, Yu HS
- KMID: 2381760
- Korean J Parasitol.
- 2015 Aug;53(4):431-438.
- doi: 10.3347/kjp.2015.53.4.431
In Trichinella spiralis infection, type 2 helper T (Th2) cell-related and regulatory T (T(reg)) cell-related immune responses are the most important immune events. In order to clarify which Toll-like receptors... -
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- The Roles of Innate Lymphoid Cells in the Development of Asthma
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Woo Y, Jeong D, Chung DH, Kim HY
- KMID: 2150805
- Immune Netw.
- 2014 Aug;14(4):171-181.
- doi: 10.4110/in.2014.14.4.171
Asthma is a common pulmonary disease with several different forms. The most studied form of asthma is the allergic form, which is mainly related to the function of Th2 cells... -
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- Modulation of Antibody Responses against Gnathostoma spinigerum in Mice Immunized with Crude Antigen Formulated in CpG Oligonucleotide and Montanide ISA720
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Intapan PM, Hirunpetcharat C, Kularbkaew C, Yutanawiboonchai W, Janwan P, Maleewong
- KMID: 1712215
- Korean J Parasitol.
- 2013 Dec;51(6):637-644.
- doi: 10.3347/kjp.2013.51.6.637
This study aimed to investigate the antibody responses in mice immunized with Gnathostoma spinigerum crude antigen (GsAg) incorporated with the combined adjuvant, a synthetic oligonucleotide containing unmethylated CpG motif (CpG... -
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- Therapeutic Effects and Immunomodulation of Suanbo Mineral Water Therapy in a Murine Model of Atopic Dermatitis
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Choi YJ, Lee HJ, Lee DH, Woo SY, Lee KH, Yun ST, Kim JM, Kim HJ, Kim JW
- KMID: 2265057
- Ann Dermatol.
- 2013 Nov;25(4):462-470.
- doi: 10.5021/ad.2013.25.4.462
BACKGROUND: Balneotherapy is widely used as an alternative treatment modality for AD. Although the clinical benefit of some mineral waters has been established, their mechanisms of action in alleviating AD... -
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- Alteration of Cytokine Production during Visceral Larva Migrans by Toxascaris leonina in Mice
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Kang SA, Park MK, Cho MK, Yu HS
- KMID: 1792153
- Korean J Parasitol.
- 2013 Oct;51(5):583-588.
To determine alteration of immune responses during visceral larva migrans (VLM) caused by Toxascaris leonina at several time points, we experimentally infected mice with embryonated eggs of T. leonina and... -
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- T cell transcriptional factors in allergic rhinitis and its association with clinical features
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Mo JH, Chung YJ, Kim JH
- KMID: 2397312
- Asia Pac Allergy.
- 2013 Jul;3(3):186-193.
- doi: 10.5415/apallergy.2013.3.3.186
BACKGROUND: Th2 cells are crucially important in allergic disease and the possible involvement of Treg and Th17 cells has not been clearly identified. OBJECTIVE: To identify the mRNA expression of T... -
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- Immunopathogenesis of Allergic Asthma: More Than the Th2 Hypothesis
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Kim YM, Kim YS, Jeon SG, Kim YK
- KMID: 2260311
- Allergy Asthma Immunol Res.
- 2013 Jul;5(4):189-196.
- doi: 10.4168/aair.2013.5.4.189
Asthma is a chronic obstructive airway disease that involves inflammation of the respiratory tract. Biological contaminants in indoor air can induce innate and adaptive immune responses and inflammation, resulting in... -
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