- Effect of Scopolamine Butylbromide on Clozapine-induced Hypersalivation in Schizophrenic Patients: A Case Series
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Takeuchi I, Suzuki T, Kishi T, Kanamori D, Hanya M, Uno J, Fujita K, Kamei H
- KMID: 2171071
- Clin Psychopharmacol Neurosci.
- 2015 Apr;13(1):109-112.
- doi: 10.9758/cpn.2015.13.1.109
Clozapine has been demonstrated to be useful for treating refractory schizophrenia. However, hypersalivation occurs in 31.0-97.4% of the patients treated with clozapine. Accordingly, some patients who are disturbed by their... -
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- Effect of Adenine on Clozapine-induced Neutropenia in Patients with Schizophrenia: A Preliminary Study
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Takeuchi I, Kishi T, Hanya M, Uno J, Fujita K, Kamei H
- KMID: 2171046
- Clin Psychopharmacol Neurosci.
- 2015 Aug;13(2):157-162.
- doi: 10.9758/cpn.2015.13.2.157
OBJECTIVE: This study examined the utility of adenine for preventing clozapine-induced neutropenia. METHODS: This retrospective study examined the effect of adenine on clozapine-induced neutropenia in patients with treatment-resistant schizophrenia and was... -
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- Acceptance of the Deltoid Muscle Injection of Aripiprazole Long-acting Injectable in the Patients with Schizophrenia
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Kamei H, Homma Y, Takeuchi I, Hajitsu G, Tozawa K, Hatano M, Fukui A, Hanya M, Yamada S, Iwata N
- KMID: 2502126
- Clin Psychopharmacol Neurosci.
- 2020 Feb;18(1):49-57.
- doi: 10.9758/cpn.2020.18.1.49
Objective: To improve poor medication adherence in schizophrenic patients, long-acting injectable (LAI) antipsychotics are used. However, it has not yet become common in Japan. Recently, aripiprazole LAI was approved for... -
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- Features and Outcomes of Children with Ulcerative Colitis who Undergo a Diagnostic Change: A Single-Center Experience
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Ito N, Takeuchi I, Kyodo R, Hirano Y, Sato T, Usami M, Shimizu H, Shimizu T, Arai K
- KMID: 2518435
- Pediatr Gastroenterol Hepatol Nutr.
- 2021 Jul;24(4):357-365.
- doi: 10.5223/pghn.2021.24.4.357
Purpose: A change in diagnosis from ulcerative colitis (UC) to Crohn's disease (CD) has been reported in pediatric inflammatory bowel disease; however, only a few clinical characteristics and predictors of... -
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- Long-Term Efficacy and Safety of Golimumab for Ulcerative Colitis in a Pediatric Inflammatory Bowel Disease Center in Japan
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Tokita K, Shimizu H, Takeuchi I, Shimizu T, Arai K
- KMID: 2535163
- Pediatr Gastroenterol Hepatol Nutr.
- 2022 Nov;25(6):461-472.
- doi: 10.5223/pghn.2022.25.6.461
Purpose: Golimumab (GLM) is an anti-tumor necrosis factor (TNF)-α antibody preparation known to be less immunogenic than infliximab (IFX) or adalimumab. Few reports on GLM in pediatric patients with ulcerative... -
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- Predictors of Small Bowel Transit Time for Capsule Endoscopy in Children with Inflammatory Bowel Disease
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Oka I, Funayama R, Shimizu H, Takeuchi I, Nojiri S, Shimizu T, Arai K
- KMID: 2544881
- Pediatr Gastroenterol Hepatol Nutr.
- 2023 Jul;26(4):181-192.
- doi: 10.5223/pghn.2023.26.4.181
Purpose: The development of assistive devices has allowed for the performance of capsule endoscopy in children. Anticipating the capsule’s transit time could affect the efficacy of the investigation and potentially... -
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- Clinical features of very early-onset inflammatory bowel disease in Japan: a retrospective single-center study
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Usami M, Takeuchi I, Kyodo R, Hirano Y, Kashiwagi K, Fujikawa H, Shimizu H, Kawai T, Arai K
- KMID: 2535821
- Intest Res.
- 2022 Oct;20(4):475-481.
- doi: 10.5217/ir.2021.00142
Background/Aims: Very early-onset inflammatory bowel disease (VEO-IBD), defined as IBD diagnosed in patients younger than 6 years, is a challenge for pediatric gastroenterologists. Although there have been reports regarding VEO-IBD... -
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- Satisfaction Survey on Antipsychotic Formulations by Schizophrenia Patients in Japan
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Hatano M, Takeuchi I, Yamashita K, Morita A, Tozawa K, Sakakibara T, Hajitsu G, Hanya M, Yamada S, Iwata N, Kamei H
- KMID: 2522958
- Clin Psychopharmacol Neurosci.
- 2021 Nov;19(4):610-617.
- doi: 10.9758/cpn.2021.19.4.610
Objective: To identify factors affecting adherence to medication, a subjective questionnaire survey was administered to schizophrenia patients regarding the prescribed antipsychotic formulations. Methods: We evaluated the patients’ satisfaction and dissatisfaction with... -
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- A Questionnaire-based Study of the Views of Schizophrenia Patients and Psychiatric Healthcare Professionals in Japan about the Side Effects of Clozapine
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Takeuchi I, Hanya M, Uno J, Amano Y, Fukai K, Fujita K, Kamei H
- KMID: 2348477
- Clin Psychopharmacol Neurosci.
- 2016 Aug;14(3):286-294.
- doi: 10.9758/cpn.2016.14.3.286
OBJECTIVE: It is well documented that clozapine treatment causes agranulocytosis, but it can also induce drowsiness, constipation, and hypersalivation; however, these symptoms are usually less severe. It has been reported... -
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- Long-Term Durability of Infliximab for Pediatric Ulcerative Colitis: A Retrospective Data Review in a Tertiary Children's Hospital in Japan
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Shimizu H, Arai K, Takeuchi I, Minowa K, Hosoi K, Sato M, Oka I, Kaburaki Y, Shimizu T
- KMID: 2510620
- Pediatr Gastroenterol Hepatol Nutr.
- 2021 Jan;24(1):7-18.
- doi: 10.5223/pghn.2021.24.1.7
Purpose: The long-term efficacy and safety of infliximab (IFX) in children with ulcerative colitis (UC) have not been well-evaluated. Here, we reviewed the long-term durability and safety of IFX in... -
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- Assessment of the Latent Adverse Events of Antipsychotic Treatment Using a Subjective Questionnaire in Japanese Patients with Schizophrenia
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Hatano M, Kamei H, Kato A, Takeuchi I, Hanya M, Uno J, Yamada S, Fujita K, Iwata N
- KMID: 2378481
- Clin Psychopharmacol Neurosci.
- 2017 May;15(2):132-137.
- doi: 10.9758/cpn.2017.15.2.132
OBJECTIVE: The adverse effects of antipsychotic agents can have a marked influence on medication adherence. In this study, we investigated the adverse events of antipsychotics that are less likely to... -
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- Longitudinal exome-wide association study to identify genetic susceptibility loci for hypertension in a Japanese population
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Yasukochi , Sakuma J, Takeuchi I, Kato K, Oguri M, Fujimaki T, Horibe H, Yamada Y
- KMID: 2402946
- Exp Mol Med.
- 2017 Dec;49(12):e409;.
- doi: 10.1038/emm.2017.209
Genome-wide association studies have identified various genetic variants associated with complex disorders. However, these studies have commonly been conducted in a cross-sectional manner. Therefore, we performed a longitudinal exome-wide association... -
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