- The ameliorating role of sofosbuvir and daclatasvir on thioacetamide-induced kidney injury in adult albino rats
-
Moustafa AH, Pasha HF, Abas MA, Aboregela AM
- KMID: 2540990
- Anat Cell Biol.
- 2023 Mar;56(1):109-121.
- doi: 10.5115/acb.22.200
Thioacetamide (TAA) exposure and hepatitis C virus infection are usually associated with renal dysfunction. Sofosbuvir (SFV) and daclatasvir (DAC) drugs combination has great value in the treatment of hepatitis C. The... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of TNF-alpha rs1800629 Polymorphism on White Matter Structures and Memory Function in Patients With Schizophrenia: A Pilot Study
-
Kang N, Shin W, Jung S, Bang M, Lee SH
- KMID: 2537385
- Psychiatry Investig.
- 2022 Dec;19(12):1027-1036.
- doi: 10.30773/pi.2021.0326
Objective This study investigated the effect of TNF-α rs1800629 polymorphism on white matter integrity and memory function in patients with schizophrenia. Methods Fifty-five participants with schizophrenia were enrolled in this study.... -
- CITED
-
- Close
- SHARE
-
- Close
- Immunomodulatory effect of the water extract of Aster tataricus through mitogen-activated protein kinase signaling pathway
-
Lee CY, Park HS, Kong DH, Kim YK, Cho Wj
- KMID: 2508484
- J Nutr Health.
- 2020 Oct;53(5):452-463.
- doi: 10.4163/jnh.2020.53.5.452
Purpose: Aster tataricus (AT) is one of the Asteraceae perennial herbs used in traditional Chinese medicine. The herb contains various bioactive substances, such as flavonoids, isoflavonoids, and phenolic compounds... -
- CITED
-
- Close
- SHARE
-
- Close
- Changes in Histopathology and Tumor Necrosis Factor-αLevels in the Hearts of Rats Following Asphyxial Cardiac Arrest
-
Lee JH, Lee TK, Kim IH, Lee JC, Won MH, Park JH, Ahn JH, Shin MC, Ohk TG, Moon JB, Cho JH, Park CW, Tae HJ
- KMID: 2394393
- J Korean Soc Emerg Med.
- 2017 Oct;28(5):449-456.
- doi: 10.0000/jksem.2017.28.5.449
PURPOSE: Post cardiac arrest (CA) syndrome is associated with a low survival rate in patients who initially have a return of spontaneous circulation (ROSC) after the CA. The aim of... -
- CITED
-
- Close
- SHARE
-
- Close
- The Efficacy of Infliximab in Refractory Uveitis
-
Kim JH, Lee DW, Cho NC
- KMID: 2213838
- J Korean Ophthalmol Soc.
- 2016 Jan;57(1):50-55.
- doi: 10.3341/jkos.2016.57.1.50
PURPOSE: To investigate the effectiveness of infliximab as treatment for refractory uveitis that recurred in spite of immunosuppressive agents. METHODS: Thirty patients who were treated for refractory uveitis from 2002 to... -
- CITED
-
- Close
- SHARE
-
- Close
- Anti-inflammatory Triterpenes and Glyceryl Glycosides from Kandelia candel (L.) Druce
-
Dat LD, Thao NP, Tai BH, Luyen BT, Yang SY, Kim S, Koo JE, Koh YS, Cuong NT, Nam NH, Thanh NV, Kiem PV, Minh CV, Kim YH
- KMID: 2312889
- Nat Prod Sci.
- 2015 Sep;21(3):150-154.
- doi: 10.0000/nps.2015.21.3.150
Phytochemical investigation of Kandelia candel resulted in the isolation of six triterpenes (1 - 5) and two glyceryl glycosides (6 and 7) and their structures were determined by comparing the... -
- CITED
-
- Close
- SHARE
-
- Close
- Involvement of PI3K/AKT and MAPK Pathways for TNF-alpha Production in SiHa Cervical Mucosal Epithelial Cells Infected with Trichomonas vaginalis
-
Yang JB, Quan JH, Kim YE, Rhee YE, Kang BH, Choi IW, Cha GH, Yuk JM, Lee YH
- KMID: 2381753
- Korean J Parasitol.
- 2015 Aug;53(4):371-377.
- doi: 10.3347/kjp.2015.53.4.371
Trichomonas vaginalis induces proinflammation in cervicovaginal mucosal epithelium. To investigate the signaling pathways in TNF-alpha production in cervical mucosal epithelium after T. vaginalis infection, the phosphorylation of PI3K/AKT and MAPK... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of the Serum Adiponectin to Tumor Necrosis Factor-alpha (TNF-alpha) Ratio on Carotid Intima-Media Thickness in Newly Diagnosed Type 2 Diabetic Patients
-
Kim KY, Hong JA, Hwang HW, Lee SH, Park JR, Yu SH, Kang JG, Ryu OH, Lee SJ, Hong EG, Kim DM, Yoo JM, Ihm SH, Choi MG, Yoo HJ, Kim CS
- KMID: 2005730
- J Lipid Atheroscler.
- 2015 Jun;4(1):7-15.
- doi: 10.12997/jla.2015.4.1.7
OBJECTIVES: Type 2 diabetes, a leading cause of cardiovascular disease, is well known for its association with accelerated atherosclerosis. Adiponectin and tumor necrosis factor - alpha (TNF-alpha), which are produced... -
- CITED
-
- Close
- SHARE
-
- Close
- Foeniculum vulgare Mill. Protects against Lipopolysaccharide-induced Acute Lung Injury in Mice through ERK-dependent NF-kB Activation
-
Lee HS, Kang P, Kim KY, Seol GH
- KMID: 2285571
- Korean J Physiol Pharmacol.
- 2015 Mar;19(2):183-189.
- doi: 10.4196/kjpp.2015.19.2.183
Foeniculum vulgare Mill. (fennel) is used to flavor food, in cosmetics, as an antioxidant, and to treat microbial, diabetic and common inflammation. No study to date, however, has assessed the... -
- CITED
-
- Close
- SHARE
-
- Close
- Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines
-
Kim SH, Kuh SU, Kim KN, Park JY, Cho KH, Chin DK, Kim KS, Cho YE
- KMID: 2352817
- Yonsei Med J.
- 2015 Jan;56(1):277-286.
- doi: 10.3349/ymj.2015.56.1.277
PURPOSE: To investigate the molecular responses of various genes and proteins related to disc degeneration upon treatment with cytokines that affect disc-cell proliferation and phenotype in living human intervertebral discs... -
- CITED
-
- Close
- SHARE
-
- Close
- Impact of smoking on the effectiveness of TNF-alpha inhibitors in patients with rheumatoid arthritis or Crohn's disease
-
Song IS, Sohn HS, Kim H, Lim E, Kwon M, Ha JH, Kwon JW
- KMID: 2050942
- Transl Clin Pharmacol.
- 2014 Dec;22(2):92-101.
- doi: 10.12793/tcp.2014.22.2.92
Cigarette smoking may be associated with the augmentation of pro-inflammatory cytokines including Tumor Necrosis Factor-alpha (TNF-alpha), which may affect the outcomes of pharmacological agents such as TNF-alpha inhibitors. The purpose... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Endurance Training on the Serum Levels of Tumour Necrosis Factor-alpha and Interferon-gamma in Sedentary Men
-
Jahromi AS, Zar A, Ahmadi F, Krustrup P, Ebrahim K, Hovanloo F, Amani D
- KMID: 2391722
- Immune Netw.
- 2014 Oct;14(5):255-259.
- doi: 10.4110/in.2014.14.5.255
Physical activity could be considered one of the factors that affect the immune system status and function. To find the relation between exercise and cytokines, we examined the possible effects... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-alpha Release from Activated Microglia and TNF-alpha Converting Enzyme Activity
-
Lee EJ, Moon PG, Baek MC, Kim HS
- KMID: 2380318
- Biomol Ther.
- 2014 Sep;22(5):414-419.
- doi: 10.4062/biomolther.2014.099
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate cell-matrix composition and are also involved in processing various bioactive molecules such as cell-surface receptors, chemokines, and cytokines. Our group recently reported... -
- CITED
-
- Close
- SHARE
-
- Close
- Medical Treatment of Ankylosing Spondylitis
-
Moon KH, Kim YT
- KMID: 2054175
- Hip Pelvis.
- 2014 Sep;26(3):129-135.
- doi: 10.5371/hp.2014.26.3.129
The diagnosis of ankylosing spondylitis is often delayed due to ambiguous clinical manifestations and strict diagnostic criteria. However, imaging techniques such as magnetic resonance imaging have been found effective for... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of plant-based Korean food extracts on lipopolysaccharide-stimulated production of inflammatory mediators in vitro
-
Lee SY, Kim YS, Lim JY, Chang N, Kang MH, Oh SY, Lee HJ, Kim H, Kim Y
- KMID: 2313736
- Nutr Res Pract.
- 2014 Jun;8(3):249-256.
BACKGROUND/OBJECTIVES: The traditional Korean diet is plant-based and rich in antioxidants. Previous studies have investigated the potential health benefits of individual nutrients of Korean foods. However, the cumulative effects of... -
- CITED
-
- Close
- SHARE
-
- Close
- Hypericum Perforatum Decreased Hippocampus TNF-alpha and Corticosterone Levels with No Effect on Kynurenine/Tryptophan Ratio in Bilateral Ovariectomized Rats
-
El-Bakly W, Hasanin AH
- KMID: 2285515
- Korean J Physiol Pharmacol.
- 2014 Jun;18(3):233-239.
- doi: 10.4196/kjpp.2014.18.3.233
The present study was designed to investigate the effect Hypericum Perforatum (HP), on behavioral changes, corticosterone, TNF-alpha levels and tryptophan metabolism and disposition in bilateral ovariectomized rats compared to 17alpha... -
- CITED
-
- Close
- SHARE
-
- Close
- Tetraspanin CD9 modulates ADAM17-mediated shedding of LR11 in leukocytes
-
Tsukamoto , Takeuchi M, Kawaguchi , Togasaki E, Yamazaki A, Sugita Y, Muto T, Sakai S, Takeda Y, Ohwada C, Sakaida E, Shimizu N, Nishii K, Jiang M, Yokote K, Bujo H, Nakaseko C
- KMID: 2155354
- Exp Mol Med.
- 2014 Apr;46(4):e89.
- doi: 10.1038/emm.2013.161
LR11, also known as SorLA or SORL1, is a type-I membrane protein from which a large extracellular part, soluble LR11 (sLR11), is released by proteolytic shedding on cleavage with a... -
- CITED
-
- Close
- SHARE
-
- Close
- Nuclear Factor-kappaB Dependent Induction of TNF-alpha and IL-1beta by the Aggregatibacter actinomycetemcomitans Lipopolysaccharide in RAW 264.7 Cells
-
Na HS, Jeong SY, Park MH, Kim S, Chung J
- KMID: 1703487
- Int J Oral Biol.
- 2014 Mar;39(1):15-22.
Aggregatibacter actinomycetemcomitans is an important pathogen in the development of localized aggressive periodontitis. Lipopolysaccharide (LPS) is a virulent factor of periodontal pathogens that contributes to alveolar bone loss and connective... -
- CITED
-
- Close
- SHARE
-
- Close
- alpha-Asarone Ameliorates Memory Deficit in Lipopolysaccharide-Treated Mice via Suppression of Pro-Inflammatory Cytokines and Microglial Activation
-
Shin JW, Cheong YJ, Koo YM, Kim S, Noh CK, Son YH, Kang C, Sohn NW
- KMID: 2048326
- Biomol Ther.
- 2014 Jan;22(1):17-26.
alpha-Asarone exhibits a number of pharmacological actions including neuroprotective, anti-oxidative, anticonvulsive, and cognitive enhancing action. The present study investigated the effects of alpha-asarone on pro-inflammatory cytokines mRNA, microglial activation, and... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinical Characteristics of Korean Rheumatoid Arthritis Patients with Indications for TNF-alpha Blocker
-
Son KM, Jung YO, Kim IJ, Kim BJ, Lee SY, Mun SY, Seo YI, Kim HA
- KMID: 2222993
- J Rheum Dis.
- 2013 Dec;20(6):356-360.
- doi: 10.4078/jrd.2013.20.6.356
OBJECTIVE: The aim of this study was to examine clinical characteristics of Korean rheumatoid arthritis (RA) patients with clinically indications for TNF-alpha blocker, and to compare their clinical parameters with... -
- CITED
-
- Close
- SHARE
-
- Close
