- Real-life experience of ledipasvir and sofosbuvir for HCV infected Korean patients: a multicenter cohort study
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Lee SK, Lee SW, Lee HL, Kim HY, Kim CW, Song DS, Chang UI, Yang JM, Yoo SH, Kwon JH, Nam SW, Kim SH, Song MJ, Lee J, Yang H, Bae SH, Han JW, Nam H, Sung PS, Jang JW, Choi JY, Yoon SK
- KMID: 2535982
- Korean J Intern Med.
- 2022 Nov;37(6):1167-1175.
- doi: 10.3904/kjim.2022.013
Background/Aims: To evaluate the efficacy and safety of ledipasvir/sofosbuvir (LDV/SOF) therapy in hepatitis C virus (HCV)-infected Korean patients in a real clinical setting. Methods: A total of 273 patients who received... -
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- Safety and effectiveness of direct-acting antivirals in patients with chronic hepatitis C and chronic kidney disease
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Ryu JE, Song MJ, Kim SH, Kwon JH, Yoo SH, Nam SW, Nam HC, Kim HY, Kim CW, Yang H, Bae SH, Song DS, Chang UI, Yang JM, Lee SW, Lee HL, Lee SK, Sung PS, Jang JW, Choi JY, Yoon SK
- KMID: 2533139
- Korean J Intern Med.
- 2022 Sep;37(5):958-968.
- doi: 10.3904/kjim.2021.486
Background/Aims: To evaluate the effectiveness and safety of direct acting antivirals (DAAs) available in chronic kidney disease (CKD) patients with hepatitis C virus (HCV) infection in Korea. Methods: In a retrospective,... -
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- Real-Life Effectiveness and Safety of Glecaprevir/Pibrentasvir for Korean Patients with Chronic Hepatitis C at a Single Institution
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Park YJ, Woo HY, Heo J, Park SG, Hong YM, Yoon KT, Kim DU, Kim GH, Kim HH, Song GA, Cho M
- KMID: 2515848
- Gut Liver.
- 2021 May;15(3):440-450.
- doi: 10.5009/gnl19393
Background/Aims: Glecaprevir/pibrentasvir (G/P) is a combination of direct-acting antiviral agents that is an approved treatment for chronic infections by all six hepatitis C virus (HCV) genotypes. However, there are limited... -
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- Clinical Utility of Mac-2 Binding Protein Glycosylation Isomer in Chronic Liver Diseases
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Tamaki N, Kurosaki M, Loomba R, Izumi N
- KMID: 2512730
- Ann Lab Med.
- 2021 Jan;41(1):16-24.
- doi: 10.3343/alm.2021.41.1.16
An accurate evaluation of liver fibrosis is clinically important in chronic liver diseases. Mac-2 binding protein glycosylation isomer (M2BPGi) is a novel serum marker for liver fibrosis. In this review,... -
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- Effects of vitamin D supplements in patients with chronic hepatitis C: a randomized, multi-center, open label study
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Jeong JY, Jun DW, Park SJ, Sohn JH, Kim SG, Lee SW, Jeong SW, Kim MY, Kim W, Shim JJ, Kim HS, Suk KT, Ahn SB
- KMID: 2505588
- Korean J Intern Med.
- 2020 Sep;35(5):1074-1083.
- doi: 10.3904/kjim.2018.273
Background/Aims: We aimed to assess the role of vitamin D supplementation in the response to pegylated interferon-α (PEG-IFN-α) plus ribavirin (RBV) treatment in patients with chronic hepatitis C (CHC). Methods: Our... -
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- An integrated analysis of elbasvir/grazoprevir in Korean patients with hepatitis C virus genotype 1b infection
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Lee YJ, Heo J, Kim DY, Chung WJ, Tak WY, Kim YJ, Paik SW, Sim E, Kulasingam S, Talwani R, Haber B, Hwang P
- KMID: 2467250
- Clin Mol Hepatol.
- 2019 Dec;25(4):400-407.
- doi: 10.3350/cmh.2019.0006
BACKGROUND/AIMS: In the Republic of Korea, an estimated 231,000 individuals have chronic hepatitis C virus (HCV) infection. The aim of the present analysis was to evaluate the safety and efficacy... -
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- Durability of Sustained Virologic Response and Improvement of Fibrosis Markers after Daclatasvir and Asunaprevir Treatment in Genotype 1b Hepatitis C Virus-Infected Patients: a Real Life and Multicenter Study
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Shin SK, Lee JW, Ra H, Kwon OS, Shin JB, Jin YJ, Lee S, Han KJ, Kim YN, Kim TH, Kim YS, Kim JH
- KMID: 2460924
- J Korean Med Sci.
- 2019 Oct;34(41):e264.
- doi: 10.3346/jkms.2019.34.e264
BACKGROUND: The long-term data with direct acting antiviral agents were rare. This study investigated the durability of a sustained virologic response (SVR) and the improvement of fibrosis after daclatasvir and... -
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- Development and surveillance of hepatocellular carcinoma in patients with sustained virologic response after antiviral therapy for chronic hepatitis C
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Na SK, Song BC
- KMID: 2459785
- Clin Mol Hepatol.
- 2019 Sep;25(3):234-244.
- doi: 10.3350/cmh.2018.0108
Hepatitis C virus (HCV) infection is a major risk factor for liver cirrhosis and hepatocellular carcinoma (HCC), and is a leading cause of liver-related deaths worldwide. Recently available direct-acting antiviral... -
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- Efficacy and Safety of Daclatasvir and Asunaprevir in Patients with Hepatitis C Virus Genotype 1b Infection on Hemodialysis
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Lee BS, Song MJ, Kwon JH, Lee TH, Jang JW, Kim SH, Lee SH, Kim HS, Kim JH, Kim SB, Ko SY, Song DS
- KMID: 2446804
- Gut Liver.
- 2019 Mar;13(2):191-196.
- doi: 10.5009/gnl18240
BACKGROUND/AIMS: We evaluated the efficacy and safety of daclatasvir (DCV) and asunaprevir (ASV) in patients with chronic hepatitis C virus (HCV) infection on hemodialysis. METHODS: We performed a single-arm, multicenter prospective... -
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- Real-World Clinical Efficacy and Tolerability of Direct-Acting Antivirals in Hepatitis C Monoinfection Compared to Hepatitis C/Human Immunodeficiency Virus Coinfection in a Community Care Setting
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Gayam V, Hossain MR, Khalid M, Chakaraborty S, Mukhtar O, Dahal S, Mandal AK, Gill A, Garlapati , Ramakrishnaiah S, Mowyad K, Sherigar J, Mansour M, Mohanty S
- KMID: 2427460
- Gut Liver.
- 2018 Nov;12(6):694-703.
- doi: 10.5009/gnl18004
BACKGROUND/AIMS: Limited data exist comparing the safety and efficacy of direct-acting antivirals (DAAs) in hepatitis C virus (HCV) monoinfected and HCV/human immunodeficiency virus (HIV) coinfected patients in the real-world clinic... -
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- The Efficacy and Safety of Direct-acting Antiviral Treatment for Chronic Hepatitis C Patients: A Single Center Study
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Park SJ, Kim AR, Choe WH, Kim JH, Yoo BC, Kwon SY
- KMID: 2424111
- Korean J Gastroenterol.
- 2018 Oct;72(4):197-204.
- doi: 10.4166/kjg.2018.72.4.197
BACKGROUND/AIMS: Direct-acting antiviral (DAA) therapy has been shown to achieve a high rate of sustained virologic response (SVR) and favorable outcomes in chronic hepatitis C (CHC) patients. We investigated the... -
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- Meta-analysis of the Efficacy and Safety of Grazoprevir and Elbasvir for the Treatment of Hepatitis C Virus Infection
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Kang MG, Kang MJ, Ji E, Yoo BK
- KMID: 2405669
- Korean J Clin Pharm.
- 2017 Sep;27(3):150-160.
- doi: 10.24304/kjcp.2017.27.3.150
OBJECTIVE: Recently, a fixed combination of grazoprevir and elbasvir (GE) has been introduced to the arsenal of chemotherapeutics to fight against this virus. The study aimed to provide information on... -
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- Real-World Single-Center Experience with Sofosbuvir-Based Regimens for the Treatment of Chronic Hepatitis C Genotype 1 Patients
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Shin HP, Burman B, Kozarek RA, Zeigler A, Wang C, Lee H, Zehr T, Edwards AM, Siddique A
- KMID: 2389360
- Gut Liver.
- 2017 Sep;11(5):711-720.
- doi: 10.5009/gnl16447
BACKGROUND/AIMS: The approval of sofosbuvir (SOF), a direct-acting antiviral, has revolutionized the treatment of chronic hepatitis C virus (HCV). METHODS: We assessed the sustained virological response (SVR) of SOF-based regimens in... -
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- Final Report of Unmet Needs of Interferon-Based Therapy for Chronic Hepatitis C in Korea: Basis for Moving into the Direct-Acting Antiviral Era
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Jang ES, Kim YS, Kim KA, Lee YJ, Chung WJ, Kim IH, Lee BS, Jeong SH
- KMID: 2412235
- Gut Liver.
- 2017 Jul;11(4):543-550.
- doi: 10.5009/gnl16530
BACKGROUND/AIMS: To evaluate the era of direct acting antivirals (DAAs), we must understand the treatment patterns and outcomes of interferon-based therapy for hepatitis C virus (HCV) infection. We aimed to... -
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- Clinical Model for Predicting Hepatocellular Carcinomas in Patients with Post-Sustained Virologic Responses of Chronic Hepatitis C: A Case Control Study
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Zeng QL, Li B, Zhang XX, Chen Y, Fu YL, Lv J, Liu YM, Yu ZJ
- KMID: 2412102
- Gut Liver.
- 2016 Nov;10(6):955-961.
- doi: 10.5009/gnl15321
BACKGROUND/AIMS: No clinical model exists to predict the occurrence of hepatocellular carcinoma in sustained virologic response-achieving (HCC after SVR) patients with chronic hepatitis C (CHC). METHODS: We performed a case-control study... -
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- A reduced dose of ribavirin does not influence the virologic response during pegylated interferon alpha-2b and ribavirin combination therapy in patients with genotype 1 chronic hepatitis C
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You BC, Kim YS, Kim HI, Kim SH, Park SS, Seo YR, Kim SG, Lee SW, Kim HS, Jeong SW, Jang JY, Kim BS
- KMID: 1392906
- Clin Mol Hepatol.
- 2012 Sep;18(3):272-278.
- doi: 10.3350/cmh.2012.18.3.272
BACKGROUND/AIMS: When combined with pegylated interferon alpha-2b (Peg-IFN alpha-2b) for the treatment of genotype 1 chronic hepatitis C (CHC) in Korea, the current guideline for the initial ribavirin (RBV) dose... -
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- The Effect of Antiviral Therapy on Serum Cholesterol Levels in Chronic Hepatitis C
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Jang ES, Won JE, Jung JI, Lee SH, Kim JW, Jeong SH
- KMID: 2284219
- Gut Liver.
- 2011 Sep;5(3):356-362.
BACKGROUND/AIMS: The aims of this study were to evaluate the effect of antiviral therapy on serum total cholesterol (TC) levels and to investigate the factors related to serum TC changes... -
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- Role of vitamin D in chronic hepatitis C
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Kim TY
- KMID: 1015579
- Korean J Hepatol.
- 2011 Jun;17(2):170-172.
- doi: 10.3350/kjhep.2011.17.2.170
No abstract available. -
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- Durability of Sustained Virologic Response in Chronic Hepatitis C: Analysis of Factors Related to Relapse after Sustained Virologic Response with Peginterferon Plus Ribavirin Combination Therapy
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Lee JE, Yoon NR, Kim JD, Song MJ, Kwon JH, Bae SH, Choi JY, Jeong SW, Yoon SK
- KMID: 1128356
- Korean J Gastroenterol.
- 2011 Mar;57(3):173-179.
- doi: 10.4166/kjg.2011.57.3.173
BACKGROUND/AIMS: Pegylated interferon plus ribavirin combination therapy has been the standard of therapy for patients with chronic hepatitis C. Although previous studies have reported long term durability after the sustained... -
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- Durability of a sustained virologic response in patients with chronic hepatitis C treated with peginterferon and ribavirin
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Kim KA
- KMID: 1105520
- Korean J Hepatol.
- 2011 Mar;17(1):84-86.
- doi: 10.3350/kjhep.2011.17.1.84
No abstract available. -
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