- Comparison of the Infant and Adult Adipose-Derived Mesenchymal Stem Cells in Proliferation, Senescence, Antioxidative Ability and Differentiation Potential
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Wu SH, Yu JH, Liao YT, Liu KH, Chiang ER, Chang MC, Wang Jp
- KMID: 2530150
- Tissue Eng Regen Med.
- 2022 Jun;19(3):589-601.
- doi: 10.1007/s13770-022-00431-x
BACKGROUND: Infant adipose-derived mesenchymal stem cells (ADSCs) collected from excised polydactyly fat tissue, which was surgical waste, could be cultured and expanded in vitro in this study. In addition, the... -
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- The Biocompatibility of Multi-Source Stem Cells and GelatinCarboxymethyl Chitosan-Sodium Alginate Hybrid Biomaterials
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Wang X, Li S, Yu H, Lv J, Fan M, Wang X, Wang X, Liang Y, Mao L, Zhao Z
- KMID: 2530143
- Tissue Eng Regen Med.
- 2022 Jun;19(3):491-503.
- doi: 10.1007/s13770-021-00429-x
BACKGROUND: Nowadays, biological tissue engineering is a growing field of research. Biocompatibility is a key indicator for measuring tissue engineering biomaterials, which is of great significance for the replacement and... -
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- Isolation of High Purity Mouse Mesenchymal Stem Cells through Depleting Macrophages Using Liposomal Clodronate
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Song JH, Kim JW, Lee MN, Oh SH, Piao X, Wang Z, Kwon SH, Kim OS, Koh JT
- KMID: 2530148
- Tissue Eng Regen Med.
- 2022 Jun;19(3):565-575.
- doi: 10.1007/s13770-021-00412-6
BACKGROUND: The use of mouse bone marrow mesenchymal stem cells (mBMSCs) represents a promising strategy for performing preclinical studies in the field of cell-based regenerative medicine; however, mBMSCs obtained via... -
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- A new strategy for stem cells therapy for erectile dysfunction: Adipose-derived stem cells transfect Neuregulin-1 gene through superparamagnetic iron oxide nanoparticles
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Cheng J, Zheng Z, Tang W, Shao J, Jiang H, Lin H
- KMID: 2529363
- Investig Clin Urol.
- 2022 May;63(3):359-367.
- doi: 10.4111/icu.20220016
Purpose: Our previous studies showed that nanotechnology improves derived adipose-derived stem cells (ADSCs) therapy for erectile dysfunction (ED). In this study, the Neuregulin-1(NRG1) gene was transfected into ADSCs with superparamagnetic... -
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- Cardiovascular Regeneration via Stem Cells and Direct Reprogramming: A Review
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Lee CS, Kim J, Cho HJ, Kim HS
- KMID: 2529865
- Korean Circ J.
- 2022 May;52(5):341-353.
- doi: 10.4070/kcj.2022.0005
Cardiovascular disease (CVD) is the leading causes of morbidity and death globally. In particular, a heart failure remains a major problem that contributes to global mortality. Considerable advancements have been... -
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- Effects and Mechanisms of Bone Marrow Mesenchymal Stem Cell Transplantation for Treatment of Ischemic Stroke in Hypertensive Rats
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Liu Y, Zhao Y, Min Y, Guo K, Chen Y, Huang Z, Long C
- KMID: 2529836
- Int J Stem Cells.
- 2022 May;15(2):217-226.
- doi: 10.15283/ijsc21136
Background and Objectives: Stroke is the most common cause of human death and functional disability, resulting in more than 5 million deaths worldwide each year. Bone marrow mesenchymal stem cells... -
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- Human Umbilical Cord Mesenchymal Stem Cells Improve the Necrosis and Osteocyte Apoptosis in Glucocorticoid-Induced Osteonecrosis of the Femoral Head Model through Reducing the Macrophage Polarization
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Tian G, Liu C, Gong Q, Yu Z, Wang H, Zhang D, Cong H
- KMID: 2529834
- Int J Stem Cells.
- 2022 May;15(2):195-202.
- doi: 10.15283/ijsc21120
Background and Objectives: Apoptosis is an outstanding determinant of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH). Human umbilical cord mesenchymal stem cells (hUC-MSCs) have been demonstrated to be associated... -
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- Single-Cell RNA Sequencing of Bone Marrow Mesenchymal Stem Cells from the Elderly People
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Zhu D, Gao J, Tang C, Xu Z, Sun T
- KMID: 2529789
- Int J Stem Cells.
- 2022 May;15(2):173-182.
- doi: 10.15283/ijsc21042
Background and Objectives: Bone marrow mesenchymal stem cells (BMSCs) show considerable promise in regenerative medicine. Many studies demonstrated that BMSCs cultured in vitro were highly heterogeneous and composed of diverse... -
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- Pharmaceutical Activation of Nrf2 Accelerates Diabetic Wound Healing by Exosomes from Bone Marrow Mesenchymal Stem Cells
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Wang L, Cai Y, Zhang Q, Zhang Y
- KMID: 2529788
- Int J Stem Cells.
- 2022 May;15(2):164-172.
- doi: 10.15283/ijsc21067
Background and Objectives: Despite advances in wound treatments, chronic diabetic wounds remain a significant medi-cal challenge. Exosomes from mesenchymal stem cells (MSCs) and small molecule activators of nuclear factor erythroid... -
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- BMP‑6 Attenuates Oxygen and Glucose Deprivation-Induced Apoptosis in Human Neural Stem Cells through Inhibiting p38 MAPK Signaling Pathway
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Wang L, Chen Y, Wei L, He J
- KMID: 2529786
- Int J Stem Cells.
- 2022 May;15(2):144-154.
- doi: 10.15283/ijsc21093
Background and Objectives: Neural stem cells (NSCs) remain in the mammalian brain throughout life and provide a novel therapeutic strategy for central nervous system (CNS) injury. Bone morphogenetic protein-6 (BMP-6)... -
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- Use of stem cells in bone regeneration in cleft palate patients: review and recommendations
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Amiri MA, Lavaee F, Danesteh H
- KMID: 2529919
- J Korean Assoc Oral Maxillofac Surg.
- 2022 Apr;48(2):71-78.
- doi: 10.5125/jkaoms.2022.48.2.71
This study was conducted to review the efficacy of different sources of stem cells in bone regeneration of cleft palate patients. The majority of previous studies focused on the transplantation... -
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- Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide
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Jiang T, Xia G, Yang B, Zhang Hw, Yin Ys, Tang Cw, Yang Jh
- KMID: 2528133
- Tissue Eng Regen Med.
- 2022 Apr;19(2):403-415.
- doi: 10.1007/s13770-021-00421-5
BACKGROUND: Endotoxemia is related to worse clinical outcomes in acute liver failure (ALF), but its management remains unsatisfactory. In this study, we aimed to assess whether the application of bone... -
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- Sources, Characteristics, and Therapeutic Applications of Mesenchymal Cells in Tissue Engineering
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Gonzalez-Vilchis RA, Piedra-Ramirez A, Patinõ-Morales CC, Sanchez-Gomez C, Beltran-Vargas NE
- KMID: 2528129
- Tissue Eng Regen Med.
- 2022 Apr;19(2):325-361.
- doi: 10.1007/s13770-021-00417-1
Tissue engineering (TE) is a therapeutic option within regenerative medicine that allows to mimic the original cell environment and functional organization of the cell types necessary for the recovery or... -
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- Isolation and Characterization of Extracellular Vesicle from Mesenchymal Stem Cells of the Epidural Fat of the Spine
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Sung SE, Seo MS, Kang KK, Choi JH, Lee SJ, Lim JH, Yang SY, Kim SK, Lee GW
- KMID: 2529521
- Asian Spine J.
- 2022 Apr;16(2):153-161.
- doi: 10.31616/asj.2021.0129
Study Design: An experimental study with extracellular vesicles (EVs) from mesenchymal stem cell (MSC) of the epidural fat (EF) of the spine. Purpose: This study aims to isolate the exosomes from... -
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- β-carotene regulates cancer stemness in colon cancer in vivo and in vitro
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Lee KE, Kwon M, Kim YS, Kim Y, Chung MG, Heo SC, Kim Y
- KMID: 2527808
- Nutr Res Pract.
- 2022 Apr;16(2):161-172.
- doi: 10.4162/nrp.2022.16.2.161
BACKGROUND/OBJECTIVES: Colorectal cancer (CRC) is the third most common cancer worldwide and has a high recurrence rate, which is associated with cancer stem cells (CSCs). β-carotene (BC) possesses antioxidant activity and... -
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- Evaluating the effect of conditioned medium from endometrial stem cells on endometriosis-derived endometrial stem cells
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Sahraei SS, Kowsari A, Asl FD, Sheykhhasan M, Naserpoor L, Sheikholeslami A
- KMID: 2527674
- Anat Cell Biol.
- 2022 Mar;55(1):100-108.
- doi: 10.5115/acb.21.169
Endometriosis is a common, benign gynecological disease which is determined as an overspreading of endometrial tissue in exterior region of the uterine cavity. Evidence suggests that retrograde menstrual blood which... -
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- A Simple Method for Generating Cerebral Organoids from Human Pluripotent Stem Cells
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Hong YJ, Lee Sb, Choi J, Yoon SH, Do JT
- KMID: 2526741
- Int J Stem Cells.
- 2022 Feb;15(1):95-103.
- doi: 10.15283/ijsc21195
Background and Objectives: In recent years, brain organoid technologies have been the most innovative advance in neural differentiation research. In line with this, we optimized a method to establish cerebral organoids... -
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- Region Specific Brain Organoids to Study Neurodevelopmental Disorders
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Susaimanickam PJ, Kiral FR, Park IH
- KMID: 2526736
- Int J Stem Cells.
- 2022 Feb;15(1):26-40.
- doi: 10.15283/ijsc22006
Region specific brain organoids are brain organoids derived by patterning protocols using extrinsic signals as opposed to cerebral organoids obtained by self-patterning. The main focus of this review is to... -
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- Combined Mesenchymal Stem Cells and Cartilage Acellular Matrix Injection Therapy for Osteoarthritis in Goats
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Kim M, Ahn J, Lee J, Song S, Lee S, Lee S, Kang KS
- KMID: 2525416
- Tissue Eng Regen Med.
- 2022 Feb;19(1):177-187.
- doi: 10.1007/s13770-021-00407-3
Background: Human umbilical cord blood-derived MSCs (hUCB-MSCs) have been studied in osteoarthritis (OA) and cartilage regeneration. Our previous study demonstrated that hUCB-MSCs combined with cartilage acellular matrix injection (CAM Inj.) represent... -
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- Stem Cell and Exosome Therapy in Pulmonary Hypertension
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Oh S, Jung JH, Ahn KJ, Jang AY, Byun K, Yang PC, Chung WJ
- KMID: 2525450
- Korean Circ J.
- 2022 Feb;52(2):110-122.
- doi: 10.4070/kcj.2021.0191
Pulmonary hypertension is a rare and progressive illness with a devastating prognosis. Promising research efforts have advanced the understanding and recognition of the pathobiology of pulmonary hypertension. Despite remarkable achievements... -
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