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Trefoil Factor 1 Suppresses Epithelial-mesenchymal Transition through Inhibition of TGF-beta Signaling in Gastric Cancer Cells

Lee DY, Song MY, Kim EH

Gastric cancer is a malignancy with high incidence and mortality worldwide. In gastric cancer, epithelial-mesenchymal transition (EMT) and metastasis further increase the mortality rate. Trefoil factor 1 (TFF1) has been...
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Visual Performance and Optical Quality after Implantation of a New Generation Monofocal Intraocular Lens

Kang KH, Song MY, Kim KY, Hwang KY, Kwon YA, Koh K

Purpose: To evaluate the performance of two intraocular lenses (IOLs). The new monofocal IOL using a higher-order aspheric optic (Tecnis Eyhance ICB00) was compared to a standard monofocal IOL (Tecnis...
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Combined Phototherapeutic Keratectomy and Peripheral Anterior Stromal Puncture for the Treatment of Recurrent Corneal Erosion Syndrome

Song MY, Chung JL, Kim KY, Hwang KY, Kwon YA, Song SW, Kim B, Koh K

Purpose: To investigate the efficacy of the combined phototherapeutic keratectomy (PTK) and peripheral anterior stromal puncture (ASP) compared with that of PTK alone in patients with recurrent corneal erosion syndrome...
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The Association between Sleep Duration and Hypertension in Non-obese Premenopausal Women in Korea

Song MY, Sung E, Jung SP, Lee KM, Keum SH, Ryu SD

BACKGROUND: Previous studies have revealed that sleep duration is linked to both obesity and hypertension. Here, we evaluated the association between sleep duration and hypertension in obese and non-obese premenopausal...
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Gender Based Health Inequality and Impacting Factors

Song MY, Lim WY, Kim JI

PURPOSE: This study was aimed to identify gender-based health inequality and explore impacting factors on health inequality in one province in Korea. METHODS: This was an explanatory study using the secondary...
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Transplantation of betacellulin-transduced islets improves glucose intolerance in diabetic mice

Song MY, Bae UJ, Jang KY, Park BH

Type 1 diabetes is an autoimmune disease caused by permanent destruction of insulin-producing pancreatic beta cells and requires lifelong exogenous insulin therapy. Recently, islet transplantation has been developed, and although...
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The efficacy of SPA0355 in protecting beta cells in isolated pancreatic islets and in a murine experimental model of type 1 diabetes

Bae UJ, Song MY, Jang HY, Gim HJ, Ryu JH, Lee SM, Jeon R, Park BH

  • KMID: 2154270
  • Exp Mol Med.
  • 2013 Nov;45(11):e51.
Cytokines activate several inflammatory signals that mediate beta-cell destruction. We recently determined that SPA0355 is a strong anti-inflammatory compound, thus reporting its efficacy in protecting beta cells from various insults....
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Codelivery of IL-7 Augments Multigenic HCV DNA Vaccine-induced Antibody as well as Broad T Cell Responses in Cynomolgus Monkeys

Park SH, Song MY, Nam HJ, Im SJ, Sung YC

BACKGROUND: A crucial limitation of DNA vaccines is its weak immunogenicity, especially in terms of eliciting antibody responses in non-human primates or humans; therefore, it is essential to enhance immune...
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Full mouth rehabilitation of the patient with severely worn dentition: a case report

Song MY, Park JM, Park EJ

The severe wear of anterior teeth facilitates the loss of anterior guidance, which protects the posterior teeth from wear during excursive movement. The collapse of posterior teeth also results in...
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Sulfuretin protects against cytokine-induced beta-cell damage and prevents streptozotocin-induced diabetes

Song MY, Jeong GS, Kwon KB, Ka SO, Jang HY, Park JW, Kim YC, Park BH

NF-kappaB activation has been implicated as a key signaling mechanism for pancreatic beta-cell damage. Sulfuretin is one of the main flavonoids produced by Rhus verniciflua, which is reported to inhibit...
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Characterization of a novel anti-human TNF-alpha murine monoclonal antibody with high binding affinity and neutralizing activity

Song MY, Park SK, Kim CS, Yoo TH, Kim B, Kim MS, Kim YS, Kwag WJ, Lee BK, Baek K

In order to develop an anti-human TNF-alpha mAb, mice were immunized with recombinant human TNF-alpha. A murine mAb, TSK114, which showed the highest binding activity for human TNF-alpha was selected...
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Coptidis rhizoma extract protects against cytokine-induced death of pancreatic beta-cells through suppression of NF-kappa B activation

Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Ka SO, Yeom SR, Kwon YD, Ryu DG, Kim KS, Park JW, Park R, Park BH

  • KMID: 1094655
  • Exp Mol Med.
  • 2007 Apr;39(2):149-159.
We demonstrated previously that Coptidis rhizoma extract (CRE) prevented S-nitroso-N-acetylpenicillamine-induced apoptotic cell death via the inhibition of mitochondrial membrane potential disruption and cytochrome c release in RINm5F (RIN) rat insulinoma...
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Effect of Nutrition-Related Education on the Acceptance of TV Food Advertisement in Middle School Students

Ko HR, Park MS, Song MY, Lee JW

  • KMID: 2301197
  • Korean J Community Nutr.
  • 2006 Feb;11(1):108-115.
This study was to investigate the effect of the education about general nutrition knowledge on the acceptance of TV food advertisements in adolescents. Twenty hours of nutrition related education in...
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Relation of the radiologic findings and labeling index of Ki-67, PCNA and cytokeratin in unicystic ameloblastoma, dentigerous cyst and odontogenic keratocyst

Song MY, Lee SS, Lee JK, Yi WJ, Heo MS, Lee JI, Min BM, Choi SC

  • KMID: 1515548
  • Korean J Oral Maxillofac Radiol.
  • 2004 Jun;34(2):75-79.
PURPOSE: To compare the proliferation potential of the epithelial cells between unicystic ameloblastoma (UA), dentigerous cyst (DC), and odontogenic keratocyst (OKC) and to correlate this proliferation potential with the radiographic...
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Production, Characterization, and Variable Region Analysis of Monoclonal Antibodies Specific for Hepatitis B Virus S Antigen

Song MY, Kim CS, Park SK, Lee JS, Yoo TH, Ko IY

BACKGROUND: Hepatitis B virus (HBV) infection is one of the worldwide public health problem affecting about 300 million people. The envelope protein of HBV consists of three components known as...
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HLA, CTLA-4 and TNF-beta Gene Polymorphisms and Disease Susceptibility in Korean Children with Graves' Disease

Song MY, Jung MH, Lee JS, Kim TG, Yang SW, Lee BC

  • KMID: 2200127
  • J Korean Soc Endocrinol.
  • 2003 Feb;18(1):32-44.
BACKGROUND: Graves' disease(GD) is an organ-specific autoimmune disorder that is inherited as a complex trait. At present three loci, namely the human leukocyte antigen(HLA), the cytotoxic T lymphocyte antigen-4(CTLA-4) and...
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Chromosomal Assay after In-vitro Irradiation of Lymphocytes in Ataxia Telangiectasia

Kim JS, Lee JY, Park SK, Kim YI, Song MY, Choi BO

  • KMID: 2342929
  • J Korean Neurol Assoc.
  • 2001 Sep;19(5):509-513.
BACKGROUND: Hypersensitivity to both cell-killing and chromosome-damaging effects of ionizing radiation is a consistent feature of cells from individuals with ataxia-telangiectasia (AT). This radiobiological behavior of AT cells is a...
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A Case of 18 Ring Chromosome

Bin JH, Song MY, Lee IG, Lee WB, Lee BC

  • KMID: 1606282
  • J Korean Pediatr Soc.
  • 2001 Jun;44(6):683-686.
A ring 18 chromosome(18r) karyotype is a rare disorder characterized by short stature, obesity, microcephaly, mental retardation, micropenis, cryptorchidism, hypertelorism, epicanthal folds, micrognathia, and small hands with short tapering fingers....
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Role of Leptin in Puberty

Song MY

  • KMID: 2193678
  • J Korean Soc Pediatr Endocrinol.
  • 2000 Jun;5(1):18-22.
No abstract available.
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A Case of Autonomous Ovarian Cyst with Severe Vaginal Bleeding

Park MY, Song MY, Lee BC

  • KMID: 2193802
  • J Korean Soc Pediatr Endocrinol.
  • 1999 Dec;4(2):231-236.
Small ovarian cysts(
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