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Recent Advances of Therapeutic Targets for the Treatment of Periodontal Disease

Kim WJ, Soh Y, Heo SM

Periodontal disease is primarily associated with bacterial infection such as dental plaque. Dental plaque, an oral biofilm harboring a complex microbial community, can cause various inflammatory reactions in periodontal tissue....
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Effect of White Matter Hyperintensity on the Functional Outcome of Ischemic Stroke Patients after Inpatient Stroke Rehabilitation

Yang M, Lee SA, Soh Y, Kim Y, Lee EJ, Yun Y, Kim JH, Chon J

The aim of the study is to investigate the association between cerebral white matter hyperintensity (WMH) and the functional improvement using the Korean version of Modified Barthel Index (K-MBI) score...
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Ultrasound-Guided Greater Occipital Nerve Block for Primary Headache: Comparison of Two Techniques by Anatomical Injection Site

Yoo MC, Kim HS, Lee JH, Yoo SD, Yun DH, Kim DH, Lee SA, Soh Y, Kim Y, Han YR, Kwon JH, Jang H, Chon J

OBJECTIVE: Greater occipital nerve block (GONB) is a widely accepted treatment of primary headaches. Two ultrasound (US)-guided blockade techniques exist: 1) the classical distal nerve block technique performed medial to...
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Association Between Asymmetry in Knee Extension Strength and Balance in a Community-Dwelling Elderly Population: A Cross-Sectional Analysis

Chon J, Kim HS, Lee JH, Yoo SD, Yun DH, Kim DH, Lee SA, Han YJ, Soh Y, Kim Y, Han YR, Won CW, Han S

OBJECTIVE: To evaluate the association between balance function and asymmetry of knee extension strength in an elderly Korean population. METHODS: The strength of the knee extensors in each leg was measured...
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Association Between a Polymorphism in CASP3 and CASP9 Genes and Ischemic Stroke

Lee BY, Chon J, Kim HS, Lee JH, Yun DH, Yoo SD, Kim DH, Lee SA, Han YJ, Lee H, Kim JC, Soh Y, Chung JH, Kim SK, Park HJ

OBJECTIVE: To investigate whether the polymorphisms of CASP3 gene (rs4647602, intron A/C and rs1049216, UTR C/T) and CASP9 gene (rs1052576, Gln/Arg G/A and rs1052571, Ser/Val T/C) were associated with the...
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The Relationship Between Tongue Pressure and Oral Dysphagia in Stroke Patients

Lee JH, Kim HS, Yun DH, Chon J, Han YJ, Yoo SD, Kim DH, Lee SA, Joo HI, Park JS, Kim JC, Soh Y

OBJECTIVE: To evaluate the relationships between tongue pressure and different aspects of the oral-phase swallowing function. METHODS: We included 96 stroke patients with dysphagia, ranging in age from 40 to 88...
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Aloe-Emodin Induces Chondrogenic Differentiation of ATDC5 Cells via MAP Kinases and BMP-2 Signaling Pathways

Yang M, Li L, Heo SM, Soh Y

Endochondral bone formation is the process by which mesenchymal cells condense into chondrocytes, which are ultimately responsible for new bone formation. The processes of chondrogenic differentiation and hypertrophy are critical...
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Evaluation of Osseointegration around Tibial Implants in Rats by Ibandronate-Treated Nanotubular Ti-32Nb-5Zr Alloy

Nepal M, Li L, Bae TS, Kim BI, Soh Y

Materials with differing surfaces have been developed for clinical implant therapy in dentistry and orthopedics. This study was designed to evaluate bone response to titanium alloy containing Ti-32Nb-5Zr with nanostructure,...
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Protective Effect of HP08-0106 on Ligature-induced Periodontitis in Rats

Choi HJ, Cho HK, Soh Y

  • KMID: 1445160
  • Int J Oral Biol.
  • 2011 Dec;36(4):187-194.
Periodontitis is an inflammatory disorder of the periodontium, characterized by destruction of the tooth supporting tissues including alveolar bone and mediated by various pro-inflammatory mediators. Here, we demonstrated that HP08-0106,...
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Protective Effect of HP08-0111 on Ligature-Induced Periodontitis

Park YR, Cho HK, Soh Y

  • KMID: 1457206
  • Int J Oral Biol.
  • 2010 Dec;35(4):145-151.
Periodontitis is an inflammatory disorder of the periodontium and is characterized by destruction of the tooth supporting tissues, mediated by the upregulation of synthesis and release of a variety of...
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Hexane-Soluble Fraction of the Common Fig, Ficus carica, Inhibits Osteoclast Differentiation in Murine Bone Marrow-Derived Macrophages and RAW 264.7 Cells

Park YR, Eun JS, Choi HJ, Nepal M, Kim DK, Seo SY, Li R, Moon WS, Cho NP, Cho SD, Bae TS, Kim BI, Soh Y

Osteoclasts, derived from multipotent myeloid progenitor cells, play homeostatic roles in skeletal modeling and remodeling, but may also destroy bone in pathological conditions such as osteoporosis and rheumatoid arthritis. Osteoclast...
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