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Histological Changes of Cervical Disc Tissue in Patients with Degenerative Ossification

Xiong Y, Yang YL, Gao YS, Wang XM, Yu X

Objective : To explore the histological feature of the cervical disc degeneration in patients with degenerative ossification (DO) and its potential mechanisms. Methods : A total of 96 surgical segments, from...
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The Effects of Retinoic Acid and MAPK Inhibitors on Phosphorylation of Smad2/3 Induced by Transforming Growth Factor β1

Lee SH, Shin JH, Shin MH, Kim YS, Chung KS, Song JH, Kim SY, Kim EY, Jung JY, Kang YA, Chang J, Park MS

BACKGROUND: Transforming growth factor β (TGF-β), retinoic acid (RA), p38 mitogen-activated protein kinase (MAPK), and MEK signaling play critical roles in cell differentiation, proliferation, and apoptosis. We investigated the effect...
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Low Level Light Therapy Using an 830-nm Light Emitting Diode Promotes Wound Healing via TGF-β/SMAD Pathway Activation

Kim SK, Soh BW, Kim YC

  • KMID: 2379898
  • Korean J Dermatol.
  • 2017 May;55(4):237-245.
BACKGROUND: The transforming growth factor-β/SMAD (TGF-β/SMAD) pathway plays an important role in tissue repair and collagen synthesis. Low-level light therapy (LLLT) is increasingly used to alleviate pain and inflammation and...
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Altered Expression of Smad Proteins in T or NK-cell Lymphomas

Go JH

  • KMID: 1972647
  • Cancer Res Treat.
  • 2008 Dec;40(4):197-201.
PURPOSE: Smad proteins mediate cellular signaling through the transforming growth factor-beta family (TGF-beta s). Smads 2 and 3 transmit signals from TGF-beta, and Smad4 is a common mediator, as well....
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