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Eculizumab as rescue therapy in a kidney transplant recipient with atypical hemolytic uremic syndrome: a case report

Oh YJ, Lee J, Kim Y, Jun H, Sim J, Kim MG, Jung CW

A 61-year-old female patient with chronic kidney disease due to diabetes mellitus and hypertension–induced nephropathy received a deceased donor kidney transplant in March 2020. In July 2020, she was transferred...
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Omission of chemotherapy for hormone receptor-positive and human epidermal growth factor receptor 2-negative breast cancer: patterns of treatment and outcomes from the Korean Breast Cancer Society Registry

Kangleon-Tan HL, Sim J, You JY, Lee ES, Lee H, Yang SM, Seong MK, Park EH, Nam SJ, Park MH, Lee S, Park WC, Kangleon Jr RG, Dy CB, Bae SY, Jung SP, Korean Breast Cancer Society

Purpose: Although adjuvant chemotherapy (CTx) is still recommended for high-risk patients with hormone receptorpositive and human epidermal receptor (HER)-2-negative breast cancer, recent studies found that selected patients with low disease...
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Association Between Insomnia and Constipation: A Multicenter Three-year Cross-sectional Study Using Shift Workers' Health Check-up Data

Yun BY, Sim J, Yoon JH, Kim SK

Background Although insomnia and constipation are highly prevalent worldwide, studies examining a possible association between them are lacking. We examined the relationship between insomnia and constipation in shift workers who have...
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Croup as a Manifestation of SARSCoV-2 Omicron Variant Infection in Young Children

Choi YY, Kim YS, Lee SY, Sim J, Choe YJ, Han MS

Croup is an acute upper respiratory disease primarily caused by the parainfluenza virus. Owing to inflammation and edema of the upper airways, children present with barky cough and stridor, and some...
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Importation and Transmission of SARS-CoV-2 B.1.1.529 (Omicron) Variant of Concern in Korea, November 2021

Lee JJ, Choe YJ, Jeong H, Kim M, Kim S, Yoo H, Park K, Kim C, Choi S, Sim J, Park Y, Huh IS, Hong G, Kim MY, Song JS, Lee J, Kim EJ, Rhee JE, Kim IH, Gwack J, Kim J, Jeon JH, Lee WG, Jeong S, Kim J, Bae B, Kim JE, Kim H, Lee HY, Lee SE, Kim JM, Park H, Yu M, Choi J, Kim J, Lee H, Jang EJ, Lim D, Lee S, Park YJ

In November 2021, 14 international travel-related severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 (omicron) variant of concern (VOC) patients were detected in South Korea. Epidemiologic investigation revealed community transmission...
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Features of the Filum Terminale in Tethered Cord Syndrome with Focus on Pathology

Sim J, Shim Y, Kim KH, Kim SK, Lee JY

Objective : Filum transection is one of the most commonly performed operative procedure in pediatric neurosurgery. However, the clinical and pathological features as well as the surgical indication are not...
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Association between postoperative fluid balance and mortality and morbidity in critically ill patients with complicated intra-abdominal infections: a retrospective study

Sim J, Kwak JY, Jung YT

Background: Postoperative fluid overload may increase the risk of developing pulmonary complications and other adverse outcomes. We evaluated the impact of excessive fluid administration on postoperative outcomes in critically ill...
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Effect of Repetitive Balloon Dilatation Treatment Confirmed by High-Resolution Manometry in a Patient with Cricopharyngeal Dysfunction: A Case Report

Sim J, Kim JM

Cricopharyngeal dysfunction (CPD) has various treatment options, such as balloon dilatation (BD), botulinum toxin injection, and myotomy of the cricopharyngeal muscle. BD is less invasive, easier to implement, and economical...
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A Single Pediatric Surgeon Working in a Single Center: Was There a Change in the Pediatric Surgeon's Role Following 25 Years of Service in Suwon City?

Hong J, Sim J

Purpose: Pediatric surgical activity is an important factor for a hospital manager when considering to hire a new pediatric surgeon. The purpose of this study was to investigate the activity...
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Usefulness of Goal Attainment Scaling in Intensive Stroke Rehabilitation During the Subacute Stage

Jung Y, Sim J, Park J, Kim J, Kim M

Objective To investigate the usefulness of goal attainment scaling (GAS) in intensive stroke rehabilitation during the subacute stage. Methods Medical records of subacute post-stroke patients who had undergone intensive rehabilitation under...
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MicroRNA-374a Expression as a Prognostic Biomarker in Lung Adenocarcinoma

Kim Y, Sim J, Kim H, Bang SS, Jee S, Park S, Jang K

BACKGROUND: Lung cancer is the most common cause of cancer-related death, and adenocarcinoma is the most common histologic subtype. MicroRNA is a small non-coding RNA that inhibits multiple target gene...
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Double H-type Tracheoesophageal Fistulae: A Case Report

Sim J, Hong J

We present an extremely rare case with double H-type tracheoesophageal fistulae identified with a time-lapse and repaired separately. A newborn male presented with cyanosis after breastfeeding. Contrast esophagogram demonstrated an...
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Neural Stem Cell Differentiation Using Microfluidic Device-Generated Growth Factor Gradient

Kim JH, Sim J, Kim HJ

Neural stem cells (NSCs) have the ability to self-renew and differentiate into multiple nervous system cell types. During embryonic development, the concentrations of soluble biological molecules have a critical role...
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Pulmonary Nodular Lymphoid Hyperplasia with Mass-Formation: Clinicopathologic Characteristics of Nine Cases and Review of the Literature

Sim J, Koh HH, Choi S, Chu J, Kim TS, Kim H, Han J

BACKGROUND: Pulmonary nodular lymphoid hyperplasia (PNLH) is a non-neoplastic pulmonary lymphoid disorder that can be mistaken for malignancy on radiography. Herein, we present nine cases of PNLH, emphasizing clinicoradiological findings...
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Anaplastic lymphoma kinase (ALK)-expressing Lung Adenocarcinoma with Combined Neuroendocrine Component or Neuroendocrine Transformation: Implications for Neuroendocrine Transformation and Response to ALK-tyrosine Kinase Inhibitors

Sim J, Kim H, Hyeon J, Choi YL, Han J

BACKGROUND: Anaplastic lymphoma kinase tyrosine kinase inhibitors (ALK-TKIs) are usually effective in lung adenocarcinoma patients with anaplastic lymphoma kinase (ALK) rearrangement. However, even after a good response to ALK-TKI therapy,...
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Treatment of Failed Arthrodesis of First Metatarsophalangeal Joint with Tensor Fascia Lata Interposition Arthroplasty: A Case Report

Sim J, Hyun Y, Park J, Kang S, Kwon H, Kim G

Surgical treatments for arthritis in the first metatarsophalangeal joint include arthrodesis, interposition arthroplasty using silicone or meniscus cartilage, and rarely arthroplasty. Although arthrodesis was performed successfully, pain can persist if...
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Clinicopathologic Correlations of E-cadherin and Prrx-1 Expression Loss in Hepatocellular Carcinoma

Yi K, Kim H, Chung Y, Ahn H, Sim J, Wi YC, Pyo JY, Song YS, Paik SS, Oh YH

BACKGROUND: Developing predictive markers for hepatocellular carcinoma (HCC) is important, because many patients experience recurrence and metastasis. Epithelial to mesenchymal transition (EMT) is a developmental process that plays an important...
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Cerebral Hemodynamics and Vascular Reactivity in Mild and Severe Ischemic Rodent Middle Cerebral Artery Occlusion Stroke Models

Sim J, Jo A, Kang BM, Lee S, Bang OY, Heo C, Jhon GJ, Lee Y, Suh M

Ischemia can cause decreased cerebral neurovascular coupling, leading to a failure in the autoregulation of cerebral blood flow. This study aims to investigate the effect of varying degrees of ischemia...
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Effects of Angiotensin-II Receptor Blocker on Inhibition of Thrombogenicity in a Canine Atrial Fibrillation Model

Choi JI, Jung JS, Kim MK, Sim J, Kim JS, Lim HE, Park SW, Kim YH

BACKGROUND AND OBJECTIVES: Angiotensin-II receptor blockers (ARBs) are known to reduce the development of atrial fibrillation (AF) through reverse-remodeling. However, the effect of ARBs on thrombogenicity in AF remains unknown. MATERIALS...
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High MicroRNA-370 Expression Correlates with Tumor Progression and Poor Prognosis in Breast Cancer

Sim J, Ahn H, Abdul R, Kim H, Yi KJ, Chung YM, Chung MS, Paik SS, Song YS, Jang K

PURPOSE: Deregulation of microRNA-370 (miR-370) has been reported in various cancers, in which it can act as either an oncogene or a tumor suppressor gene. However, the clinicopathologic significance of...
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