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Apigenin Inhibits Tumor Necrosis Factor-alpha-Induced Production and Gene Expression of Mucin through Regulating Nuclear Factor-Kappa B Signaling Pathway in Airway Epithelial Cells

Seo HS, Sikder MA, Lee HJ, Ryu J, Lee CJ

In the present study, we investigated whether apigenin significantly affects tumor necrosis factor-alpha (TNF-alpha)-induced production and gene expression of MUC5AC mucin in airway epithelial cells. Confluent NCI-H292 cells were pretreated...
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Apigenin and Wogonin Regulate Epidermal Growth Factor Receptor Signaling Pathway Involved in MUC5AC Mucin Gene Expression and Production from Cultured Airway Epithelial Cells

Sikder MA, Lee HJ, Ryu J, Park SH, Kim JO, Hong JH, Seok JH, Lee CJ

  • KMID: 2320493
  • Tuberc Respir Dis.
  • 2014 Mar;76(3):120-126.
BACKGROUND: We investigated whether wogonin and apigenin significantly affect the epidermal growth factor receptor (EGFR) signaling pathway involved in MUC5AC mucin gene expression, and production from cultured airway epithelial cells;...
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Effect of Prunetin on TNF-alpha-Induced MUC5AC Mucin Gene Expression, Production, Degradation of IkappaB and Translocation of NF-kappaB p65 in Human Airway Epithelial Cells

Ryu J, Lee HJ, Park SH, Sikder MA, Kim JO, Hong JH, Seok JH, Lee CJ

  • KMID: 2320469
  • Tuberc Respir Dis.
  • 2013 Nov;75(5):205-209.
BACKGROUND: We investigated whether prunetin significantly affects tumor necrosis factor-alpha (TNF-alpha)-induced MUC5AC mucin gene expression, production, inhibitory kappa B (IkappaB) degradation and nuclear factor kappa B (NF-kappaB) p65 translocation in...
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Effect of Chrysin on Gene Expression and Production of MUC5AC Mucin from Cultured Airway Epithelial Cells

Shin HD, Lee HJ, Sikder MA, Park SH, Ryu J, Hong JH, Kim JO, Seok JH, Lee CJ

  • KMID: 2320194
  • Tuberc Respir Dis.
  • 2012 Oct;73(4):204-209.
BACKGROUND: We investigated whether chrysin affected MUC5AC mucin production and gene expression induced by phorbol ester (phorbol 12-myristate 13-acetate, PMA) or epidermal growth factor (EGF) from human airway epithelial cells. METHODS:...
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