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Inhalation of Clary Sage Oil before Chemotherapy Alleviates Anxiety and Stress without Changing Blood Pressure: A Randomized Controlled Trial

Kim M, Shin YK, Seol GH

Purpose: The purpose of this study was to evaluate the effects of inhaled clary sage (Salvia sclarea L.) oil or linalyl acetate on patients’ anxiety and stress levels before undergoing...
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Comparison of oncologic outcomes between patients with Lynch syndrome and sporadic microsatellite instability-high colorectal cancer

Son IT, Kim DW, Kim MH, Shin YK, Ku JL, Oh HK, Kang SB, Jeong SYJ, Park KJ

Purpose: Long-term oncologic differences in outcome between groups of patients with Lynch syndrome (LS) colorectal cancer (CRC) and sporadic CRC with microsatellite instability-high (MSI-H) are the focus of investigation in...
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Early Retinal Hemorrhage Absorption Rate and Long Term Clinical Outcomes in Branch Retinal Vein Occlusion

Kim YB, Lee CH, Shin YK, Kyung SE, Seo YS

Purpose: We report the relationship between early retinal hemorrhage absorption rate (RHAR) and long-term clinical outcomes associated with branch retinal vein occlusion (BRVO). Methods: This retrospective study included 66 eyes with...
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TM4SF4 and LRRK2 Are Potential Therapeutic Targets in Lung and Breast Cancers through Outlier Analysis

Jung K, Choi JS, Koo BM, Kim YJ, Song JY, Sung M, Chang ES, Noh KW, An S, Lee MS, Song K, Lee H, Kim RN, Shin YK, Oh DY, Choi YL

Purpose To find biomarkers for disease, there have been constant attempts to investigate the genes that differ from those in the disease groups. However, the values that lie outside the overall...
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Direct reprogramming of fibroblasts into diverse lineage cells by DNA demethylation followed by differentiating cultures

Yang DW, Moon J, Ko HM, Shin YK, Fukumoto S, Kim SH, Kim MS

Direct reprogramming, also known as a trans-differentiation, is a technique to allow mature cells to be converted into other types of cells without inducing a pluripotent stage. It has been...
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The Scaffolding Protein, Grb2-associated Binder-1, in Skeletal Muscles and Terminal Schwann Cells Regulates Postnatal Neuromuscular Synapse Maturation

Park SY, Jang SY, Shin YK, Jung DK, Yoon BA, Kim JK, Jo YR, Lee HJ, Park HT

The vertebrate neuromuscular junction (NMJ) is considered as a “tripartite synapse” consisting of a motor axon terminal, a muscle endplate, and terminal Schwann cells that envelope the motor axon terminal....
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A serological study of severe fever with thrombocytopenia syndrome using a virus neutralization test and competitive enzyme-linked immunosorbent assay

Lee H, Kim EJ, Cho IS, Song JY, Choi JS, Lee JY, Shin YK

Severe fever with thrombocytopenia syndrome (SFTS) is caused by the SFTS virus (SFTSV). The SFTSV appears to have a wide host range, as SFTSV-positive ticks have been isolated from both...
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Development and evaluation of an immunochromatographic assay using a gp51 monoclonal antibody for the detection of antibodies against the bovine leukemia virus

Kim EJ, Cheong KM, Joung HK, Kim BH, Song JY, Cho IS, Lee KK, Shin YK

Infection of cattle with bovine leukemia virus (BLV) has been observed and reported worldwide, including in Korea. The onsite identification of infected cattle would help decreasing and eradicating BLV infections...
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Anti-cancer Activity of Anthricin through Caspase-dependent Apoptosis in Human Hypopharyngeal Squamous Carcinoma Cell

Kim WG, Lee SA, Moon SM, Kim JS, Kim SG, Shin YK, Kim DK, Kim CS

Anthricin (Deoxypodophyllotoxin), a naturally occurring flavolignan, has well known anti-cancer properties in several cancer cells, such as prostate cancer, cervical carcinoma and pancreatic cancer. However, the effects of Anthricin are...
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Uracil-DNA glycosylase-treated reverse transcription loop-mediated isothermal amplification for rapid detection of avian influenza virus preventing carry-over contamination

Kim EM, Jeon HS, Kim JJ, Shin YK, Lee YJ, Yeo SG, Park CK

Here, we describe a uracil-DNA glycosylase (UNG)-treated reverse transcription loop-mediated isothermal amplification (uRT-LAMP) for the visual detection of all subtypes of avian influenza A virus (AIV). The uRT-LAMP assay can...
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Development and evaluation of a competitive enzyme-linked immunosorbent assay using a monoclonal antibody for diagnosis of severe fever with thrombocytopenia syndrome virus in bovine sera

Lee H, Kim EJ, Song JY, Choi JS, Lee JY, Cho IS, Shin YK

Severe fever with thrombocytopenia syndrome (SFTS) caused by the SFTS virus (SFTSV), a phlebovirus in the family Bunyaviridae, is an emerging tick-borne infectious disease that impacts humans. This disease manifests...
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Altered Biological Potential and Radioresponse of Murine Tumors in Different Microenvironments

Lee IJ, Lee EJ, Park H, Kim W, Ha SJ, Shin YK, Seong J

PURPOSE: This study was conducted to evaluate the biological features of murine hepatocarcinoma according to different tumor microenvironmental models and to determine the change in molecular and immunologic responses after...
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Validation of Prediction Models for Mismatch Repair Gene Mutations in Koreans

Lee SY, Kim DW, Shin YK, Ihn MH, Lee SM, Oh HK, Ku JL, Jeong SY, Lee JB, Ahn S, Won S, Kang SB

PURPOSE: Lynch syndrome, the commonest hereditary colorectal cancer syndrome, is caused by germline mutations in mismatch repair (MMR) genes. Three recently developed prediction models for MMR gene mutations based on...
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Clinicopathological Features and Type of Surgery for Lynch Syndrome: Changes during the Past Two Decades

Son IT, Kim DW, Jeong SY, Shin YK, Ihn MH, Oh HK, Kang SB, Park KJ, Oh JH, Ku JL, Park JG

PURPOSE: The Korean Hereditary Tumor Registry, the first and one of the largest registries of hereditary tumors in Korea, has registered about 500 families with hereditary cancer syndromes. This study...
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Oxidative damage biomarker levels according to Mn-SOD and GST gene polymorphisms in preschool children

Shin YK, Choi JW, Oh SY, Chung J

PURPOSE: Genetic polymorphisms in antioxidant defense and detoxification genes may modulate the levels of oxidative stress biomarkers. METHODS: A total of 301 healthy preschool-aged children in the Seoul and Kyung-gi areas...
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Effect of Rhythmic Auditory Stimulation on Hemiplegic Gait Patterns

Shin YK, Chong HJ, Kim SJ, Cho SR

PURPOSE: The purpose of our study was to investigate the effect of gait training with rhythmic auditory stimulation (RAS) on both kinematic and temporospatial gait patterns in patients with hemiplegia. MATERIALS...
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Dose-dependent Changes in Gait Pattern after Intrathecal Baclofen Bolus Injection in Adult Ambulatory Cerebral Palsy: A Case Report

Shin YK, Kim AR, Chang JW, Chang WS, Lee DS, Cho SR

Intrathecal baclofen (ITB) therapy has been proven to reduce severe spasticity in cerebral palsy (CP). However, few results reported the objective gait pattern change after ITB bolus injection in adult...
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Changes in Hyolaryngeal Movement and Swallowing Function After Neuromuscular Electrical Stimulation in Patients With Dysphagia

Lee HY, Hong JS, Lee KC, Shin YK, Cho SR

OBJECTIVE: To investigate immediate changes in hyolaryngeal movement and swallowing function after a cycle of neuromuscular electrical stimulation (NMES) on both submental and throat regions and submental placement alone in...
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The Effect of Treadmill Exercise on Gait Efficiency During Overground Walking in Adults With Cerebral Palsy

Kim OY, Shin YK, Yoon YK, Ko EJ, Cho SR

OBJECTIVE: To investigate the effect of treadmill walking exercise as a treatment method to improve gait efficiency in adults with cerebral palsy (CP) and to determine gait efficiency during overground...
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Comparison of Clinical Results between 2.2 mm and 2.8 mm Incision Cataract Surgery Using Ellips Ultrasound

Ghim WH, Shin YK, Cho KJ

PURPOSE: Introduction of phacoemulsification and development of foldable artificial lens has facilitated smaller incisions, even micro-coaxial incisions. However, there have been several studies showing that micro-coaxial incision has no benefit...
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