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Attenuation of Experimental Autoimmune Uveitis in Lewis Rats by Betaine

Choi Y, Jung K, Kim HJ, Chun J, Ahn M, Jee Y, Ko HJ, Moon C, Matsuda H, Tanaka A, Kim J, Shin T

  • KMID: 2519892
  • Exp Neurobiol.
  • 2021 Aug;30(4):308-317.
  • doi: 10.5607/en21011
Experimental autoimmune uveitis (EAU) is an animal model of human autoimmune uveitis that is characterized by the infiltration of autoimmune T cells with concurrent increases in pro-inflammatory cytokines and reactive...
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Perceived Dark Rim Artifact in First-Pass Myocardial Perfusion Magnetic Resonance Imaging Due to Visual Illusion

Shin T, Nayak KS

OBJECTIVE: To demonstrate that human visual illusion can contribute to sub-endocardial dark rim artifact in contrast-enhanced myocardial perfusion magnetic resonance images. MATERIALS AND METHODS: Numerical phantoms were generated to simulate the...
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The individual and neighborhood factors associated with the use of emergency medical services in patients with ST-elevation myocardial infarction

Choi H, Cha WC, Jo IJ, Choi JH, Sim MS, Shin T

Objective The utilization of emergency medical services (EMS) varies widely among communities. In this study, we aimed to evaluate the relationship between the use of EMS by patients with ST-elevation...
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The Risk Factors and Clinical Features of Posttraumatic Seizure in Preschool-Aged Children

Shin T, Oh K, Cha BH

PURPOSE: This study aimed to identify the clinical characteristics and risk factors of post-traumatic seizure (PTS) in preschool-aged children. METHODS: This study is based on a retrospective electronic medical record review...
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Gene Expression Profile of Olfactory Transduction Signaling in an Animal Model of Human Multiple Sclerosis

Kim J, Ahn M, Choi Y, Ekanayake , Park CM, Moon C, Jung K, Tanaka A, Matsuda H, Shin T

Olfactory dysfunction occurs in multiple sclerosis in humans, as well as in an animal model of experimental autoimmune encephalomyelitis (EAE). The aim of this study was to analyze differentially expressed...
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Immunohistochemical localization of nerve injury-induced protein-1 in mouse tissues

Ekanayake , Ahn M, Kim J, Choi Y, Shin T

Nerve injury-induced protein (Ninjurin)-1 is a cell adhesion molecule that is upregulated in neurons and Schwann cells after transection injury in rats. In this study, we investigated the localization of...
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Benefits of hesperidin in central nervous system disorders: a review

Kim J, Wie MB, Ahn M, Tanaka A, Matsuda H, Shin T

Citrus species contain significant amounts of flavonoids that possess antioxidant activities; furthermore, dietary citrus is not associated with adverse effects or cytotoxicity in healthy individuals. Hesperidin, which is an abundant...
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Two-Dimensional Image-Based Respiratory Navigator for Free-Breathing Coronary Magnetic Resonance Angiography

Shin T

PURPOSE: To develop a two-dimensional (2D) image-based respiratory motion correction technique for free-breathing coronary magnetic resonance angiography (MRA). MATERIALS AND METHODS: The proposed respiratory navigator obtained aliased a 2D sagittal image...
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Amelioration of experimental autoimmune encephalomyelitis by Ishige okamurae

Ahn M, Kim J, Yang W, Choi Y, Ekanayake , Ko H, Jee Y, Shin T

Experimental autoimmune encephalomyelitis (EAE) is a T-cell-mediated autoimmune central nervous system disease characterized by inflammation with oxidative stress. The aim of this study was to evaluate an anti-inflammatory effect of...
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Chronic Treatment with Combined Chemotherapeutic Agents Affects Hippocampal Micromorphometry and Function in Mice, Independently of Neuroinflammation

Kang S, Lee S, Kim J, Kim JC, Kim SH, Son Y, Shin T, Youn B, Kim JS, Wang H, Yang M, Moon C

Chemotherapeutic agents induce long-term side effects, including cognitive impairment and mood disorders, particularly in breast cancer survivors who have undergone chemotherapy. However, the precise mechanisms underpinning chemotherapy-induced hippocampal dysfunction remain...
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Lithium ameliorates rat spinal cord injury by suppressing glycogen synthase kinase-3β and activating heme oxygenase-1

Kim Y, Kim J, Ahn M, Shin T

Glycogen synthase kinase (GSK)-3β and related enzymes are associated with various forms of neuroinflammation, including spinal cord injury (SCI). Our aim was to evaluate whether lithium, a non-selective inhibitor of...
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Potential involvement of glycogen synthase kinase (GSK)-3β in a rat model of multiple sclerosis: evidenced by lithium treatment

Ahn M, Kim J, Park C, Cho J, Jee Y, Jung K, Moon C, Shin T

Glycogen synthase kinase (GSK)-3β has been known as a pro-inflammatory molecule in neuroinflammation. The involvement of GSK-3β remains unsolved in acute monophasic rat experimental autoimmune encephalomyelitis (EAE). The aim of...
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Fucoidan attenuates 6-hydroxydopamine-induced neurotoxicity by exerting anti-oxidative and anti-apoptotic actions in SH-SY5Y cells

Kim MH, Namgoong H, Jung BD, Kwon MS, Choi YS, Shin T, Kim HC, Wie MB

Parkinson's disease (PD) is an irreversible neurological disorder with related locomotor dysfunction and is haracterized by the selective loss of nigral neurons. PD can be experimentally induced by 6-hydroxydopamine (6-OHDA)....
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Appearance of osteoporosis in rat experimental autoimmune encephalomyelitis

Ahn M, Kang S, Park C, Kim J, Jung K, Yang M, Kim SH, Moon C, Shin T

Experimental autoimmune encephalomyelitis (EAE) in Lewis rats is characterized by transient paralysis followed by recovery. To evaluate whether transient paralysis in EAE affects bone density, tibiae of EAE rats were...
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A study of animal bones excavated from the shell mound of Jeju Jongdali 1819 archaeological site

Kang Y, Moon J, Ahn M, Bang MB, Shin T

  • KMID: 1700785
  • Korean J Vet Res.
  • 2014 Mar;54(1):13-19.
Animal bones excavated with earthenware from the shell mound at the Jeju Jongdali 1819 archeological site, where three consecutive chronological layers covering the Neolithic (B.C. 15C-B.C. 10C), early Tamra, and...
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Increased expression of galectin-9 in experimental autoimmune encephalomyelitis

Cho J, Bing SJ, Kim A, Yu HS, Lim YK, Shin T, Choi J, Jee Y

Experimental autoimmune encephalomyelitis (EAE), an animal model of human multiple sclerosis (MS), reflects pathophysiologic steps in MS such as the influence of T cells and antibodies reactive to the myelin...
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Immunohistochemical localization of galectin-3 in the brain with Theiler's murine encephalomyelitis virus (DA strain) infection

Shin T, Carrillo-Salinas FJ, Feliu Martinez A, Mecha M, Guaza C

  • KMID: 1884015
  • Korean J Vet Res.
  • 2013 Sep;53(3):159-162.
Galectin-3 is a beta-galactoside-binding lectin that plays a role in neuroinflammation through cell migration, proliferation, and apoptosis. In the present study, regulation of galectin-3 was examined in the brain of...
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A morphological study of vomeronasal organ of Korean black goat (Capra aegagrus hircus)

Park C, Yang W, Bae Y, Lee Y, Kang W, Ahn M, Shin T

  • KMID: 1991794
  • Korean J Vet Res.
  • 2013 Mar;53(1):55-60.
The vomeronasal organ (VNO) plays an important role in reproduction and social activities in ruminants including goats. A morphological study on the structure of VNO and its epithelial cells was...
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Mechanism of experimental autoimmune encephalomyelitis in Lewis rats: recent insights from macrophages

Shin T, Ahn M, Matsumoto

Experimental autoimmune encephalomyelitis (EAE) in Lewis rats is an acute monophasic paralytic central nervous system disease, in which most rats spontaneously recover from paralysis. EAE in Lewis rats is induced...
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Bronchoscopic Ethanolamine Injection Therapy in Patients with Persistent Air Leak from Chest Tube Drainage

Lim AL, Kim CH, Hwang YI, Lee CY, Choi JH, Shin T, Park YB, Jang SH, Park SM, Kim DG, Lee MG, Hyun IG, Jung KS, Shin HS

  • KMID: 2319818
  • Tuberc Respir Dis.
  • 2012 May;72(5):441-447.
BACKGROUND: Chest tube drainage (CTD) is an indication for the treatment of pneumothorax, hemothroax and is used after a thoracic surgery. But, in the case of incomplete lung expansion, and/or...
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