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Case Analysis in Drug Approval by FDA/EMA Using Real-World Data/Real-World Evidence

Song J, Kim J, Park S, Kim JH, Noh Y, Sung HG, Shin JY

In recent years, regulators have been willing to use real-world data (RWD) and real-world evidence (RWE) to support their regulatory decisions in various areas, such as initial marketing authorizations, expanding...
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Diffuse Hemangiomatosis in the Intra-Abdominal Cavity Mimicking Peritoneal Metastasis: A Case Report

Ahn WI, Shin JY, Choi JW

We call hemangiomatosis if hemangioma arises multifocally from single or multiple organs. It develops predominantly on liver, and there are just few cases of hemangiomatosis from greater omentum and mesentery....
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Results and Factors Affecting Clinical Efficacy of Medial Patellofemoral Ligament Reconstruction Using a Gracilis Tendon Suture Technique

Kim HJ, Shin JY, Kim KR, Lee HJ, Park KH, Kim JW, Oh CW, Kyung HS

Background: This study evaluated the outcomes of medial patellofemoral ligament (MPFL) reconstruction using a gracilis tendon suture technique for patients with patellar instability. Potential factors affecting clinical efficacy were also...
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Psychological Effects of COVID-19 Patient Management Experience among Paramedics and Emergency Medical Technicians: A Nationwide Survey in Korea

Kim B, Kwon KT, Hwang S, Ryoo HW, Chung US, Lee SH, Lee JY, Park HY, Shin JY, Bae Sg

Background: Throughout the coronavirus disease 2019 (COVID-19) pandemic, not only medical personnel but also paramedics or emergency medical technicians (EMT) have faced multiple physical and psychological challenges while performing their...
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Comparison of Expedited Reporting System for Investigational Drugs in the U .S., EU and South Korea

Cha JW, Rhee HE, Park SJ, Kim S, Cho HK, Lee JE, Lee B, Shim DY, Shin JY

As the number of clinical trials conducted worldwide continues to increase, the management of safety information of investigational medicinal products used during clinical trials has become ever more important. Individual...
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Trends in Prescribing of Antiseizure Medications in South Korea: Real-World Evidence for Treated Patients With Epilepsy

Kang KW, Lee H, Shin JY, Moon HJ, Lee SY

Background and Purpose We investigated the trends in the prescribing of antiseizure medication (ASM) over a 9-year period, and provide real-world data regarding ASM prescriptions of patients with epilepsy in...
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Trend of Antibiotic Use in Children with Acute Otitis Media in Korea

Park KH, Choe SA, Shin JY, Choe YJ

Public interventions have shown to optimize the use of antibiotics in children with acute otitis media (AOM). In this study, we describe the AOM-related antibiotic use among children in South...
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Survival, Prognosis, and Clinical Feature of Refractory Myasthenia Gravis: a 15-year Nationwide Cohort Study

Jeong S, Noh Y, Oh IS, Hong YH, Shin JY

Background: Myasthenia gravis (MG) is a rare classic autoimmune disease where immunosuppressant therapies have been successful to reduce MG attributable mortality fairly well. However, patients with refractory MG (rMG) among...
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Comparison of Postmarket Surveillance Strategies of Implantable Medical Devices in the United States, European Union, and South Korea

Cho Yo, Lee JYe, Shim DaYo, Park SJ, Rhee HE, Sung HG, Kim HJ, Choi NK, Song HJ, K im JA, Park Sm, Shin JY

The biomedical industry is making rapid progresses like never before, and the number of adverse events caused by implantable medical devices is also increasing. As such, there is an ever-growing...
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Arthralgia and Myalgia Associated with the Use of Bisphosphonate: An Active Monitoring Study

Song Jw, Park SH, Yoon D, Lee MS, Lee JM, Kim NY, Kim YW, Lee JY, Shin JY

Objective: We investigated arthralgia and myalgia associated with the use of oral bisphosphonate (BP) by conducting a survey of patient. Methods: The pharmacists conducted a survey between 1 Oct 2019...
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Meta-analysis of transanal versus laparoscopic total mesorectal excision for rectal cancer: a ‘New Health Technology’ assessment in South Korea

Kwon SH, Joo YI, Kim SH, Lee DH, Baek JH, Chung SS, Shin JY, Eun CS, Kim NK

Purpose: Under the South Korea’s unique health insurance structure, any new surgical technology must be evaluated first by the government in order to consider whether that particular technology can be...
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Cephalic Vein Supercharging to Prevent Venous Congestion for a Reverse Radial Forearm Flap Used in the Reconstruction of Dorsum of Hand: A Case Report

Kim JL, Chun JY, Lee NH, Shin JY, Roh SG

The reverse radial forearm flap is often co-opted for soft tissue reconstruction of the dorsum of hand. Venous congestion can lead to flap necrosis or failure. To improve dorsum hand...
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Increasing Trends in the Incidence and Prevalence of Epilepsy in Korea

Jeon JY, Lee H, Shin JY, Moon HJ, Lee SY, Kim JM, on behalf of Epidemiology Committee of Korean Epilepsy Society

Background and Purpose There have been few reports on recent trends in the occurrence of epilepsy. The aim of this study was to estimate the incidence and prevalence of epilepsy...
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Exploring the Perception on Drug Utilization Review System and DUR Modernization Pilot Project: A Qualitative Study Using Focus Group Interviews

Bea S, Jeon HL, Yoon D, Choi A, Lee H, Shin JY

Objective: To explore the perception of drug utilization review (DUR) system and DUR modernization pilot project among healthcare professionals and patients. Methods: We conducted 8 times of focus group interviews...
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Ectopic Male Breast Cancer in Suprapubic Area That Relapsed with Hematogenous Metastasis

Byon JH, An AR, Shin JY, Choi EJ

Tough ectopic male breast cancer is extremely rare, non-axillary ectopic male breast cancer is even rare. To date, the natural course and prognosis of this disease are not fully understood. Consequently,...
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Effects of perioperative radiation treatment on stricture and fistula formation in hypopharyngeal reconstruction: a meta-analysis

Shin JY, Lee SY, Roh SG, Lee NH

Hypopharyngeal reconstruction is a surgically challenging procedure, and postoperative management is important due to a high rate of complications following surgery. In particular, stricture and fistula formation is the most...
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A survey for Management of Drug Safety Evaluation System for Investigational Product

Lee BM, Park SJ, Shim DY, Rhee HE, Lee JE, Kim SH, Cho HK, Shin JY

Objective: To gather the opinions of hands-on workers for successful introduction of the Development Safety Update Report (DSUR) according to a five-year comprehensive plan for clinical trial development [Ministry of...
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Treatment Patterns of Osteoporosis and Factors Affecting the Prescribing of Bone-forming Agents: From a National Health Insurance Claims Database

Jeong J, Shin JY

Objective: To analyze osteoporosis treatment patterns and teriparatide prescription-associated factors in Korea by using a national health insurance claims database. Methods: We utilized the Health Insurance Review & Assessment Service...
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A Clinical and Histopathological Review of Sweet Syndrome in Korean Children and Adolescents

Shin JY, Lee JY, Yoon TY

  • KMID: 2514426
  • Korean J Dermatol.
  • 2021 Mar;59(3):167-174.
Background: Sweet syndrome is characterized by tender erythematous plaques and nodules with predominantly dermal neutrophilic infiltrates. Sweet syndrome is relatively rare in children and adolescents. To date, only a few...
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Interdigitating Dendritic Cell Sarcoma in Upper Arm Misdiagnosed as Ruptured Epidermal Inclusion Cyst

Chun JY, Roh SG, Kim JL, Shin JY, Chang SC, Lee NH

Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare neoplasm that usually arises in lymph nodes, but also can exist in extranodal sites. This report is about a case study...
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