- Aggressive Digital Papillary Adenoma of the Right Big Toe: A Case Report
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Noh H, Kim HY, Shin DM, Jang D, Shim J, Oh SJ, Lee JH, Lee DY, Lee JH, Park JH
- KMID: 2536320
- Korean J Dermatol.
- 2022 Nov;60(9):597-600.
Aggressive digital papillary adenoma (ADPA) is a rare tumor of the sweat glands. They usually present as solitary masses, with or without pain, and are most commonly observed in the... -
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- Clinical Benefit of Early Laser Treatment of Scars in Children: A Single-Center Retrospective Study
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Lee J, Shin DM, Jang D, Oh SJ, Kim HJ, Lee JH
- KMID: 2519502
- Korean J Dermatol.
- 2021 Aug;59(7):507-512.
Background: Scars in children are highly concerning to most parents who usually seek prompt treatment for these lesions. However, compared with adults, children show a greater tendency to develop hypertrophic... -
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- Laparoscopic repeated pancreatectomy for isolated local recurrence in remnant pancreas following laparoscopic radical pancreatectomy for pancreatic ductal adenocarcinoma: Two cases report
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Choi M, Lee SJ, Shin DM, Hwang HK, Lee WJ, Kang CM
- KMID: 2508867
- Ann Hepatobiliary Pancreat Surg.
- 2020 Nov;24(4):542-546.
- doi: 10.14701/ahbps.2020.24.4.542
Typical treatment for recurrent pancreatic cancer is potent chemotherapy or chemoradiotherapy. However, recent clinical investigations suggest a potential therapeutic role of local resection in recurrent pancreatic cancer. Based on accumulating... -
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- Deficiencies of Homer2 and Homer3 accelerate aging-dependent bone loss in mice
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Kang JY, Kang N, Shin DM, Yang YM
- KMID: 2507078
- Int J Oral Biol.
- 2020 Sep;45(3):126-133.
- doi: 10.11620/IJOB.2020.45.3.126
Homer proteins are scaffold proteins that regulate calcium (Ca2+) signaling by modulating the activity of multiple Ca2+ signaling proteins. In our previous report, Homer2 and Homer3 regulated NFATc1 function through... -
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- Homer2 regulates amylase secretion via physiological calcium oscillations in mouse parotid gland acinar cells
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Kang N, Kang JY, Shin DM, Yang YM
- KMID: 2504256
- Int J Oral Biol.
- 2020 Jun;45(2):58-63.
- doi: 10.11620/IJOB.2020.45.2.58
The salivary glands secrete saliva, which plays a role in the maintenance of a healthy oral environment. Under physiological conditions, saliva secretion within the acinar cells of the gland is... -
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- Effect of a Single Bout of Exercise on Autophagy Regulation in Skeletal Muscle of High-Fat High-Sucrose Diet-Fed Mice
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Zhang D, Lee JH, Kwak SE, Shin HE, Zhang Y, Moon HY, Shin DM, Seong JK, Tang L, Song W
- KMID: 2459812
- J Obes Metab Syndr.
- 2019 Sep;28(3):175-185.
- doi: 10.7570/jomes.2019.28.3.175
BACKGROUND: Autophagy maintains metabolic homeostasis of muscles, and its impairment may cause muscle dysfunction. Exercise can improve muscle dysfunction induced by long-term high-fat diet. This study aimed to explore the... -
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- Humanin suppresses receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation via AMP-activated protein kinase activation
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Kang N, Kim KW, Shin DM
- KMID: 2455817
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):411-417.
- doi: 10.4196/kjpp.2019.23.5.411
Humanin (HN) is a mitochondrial peptide that exhibits cytoprotective actions against various stresses and diseases. HN has been shown to induce the phosphorylation of AMP-activated protein kinase (AMPK), which is... -
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- Monitoring Glutathione Dynamics and Heterogeneity in Living Stem Cells
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Jeong EM, Shin JW, Lim J, Kim JH, Kang H, Yin Y, Kim HM, Kim Y, Kim SG, Kang HS, Shin DM, Choi K, Kim IG
- KMID: 2465906
- Int J Stem Cells.
- 2019 Jul;12(2):367-379.
- doi: 10.15283/ijsc18151
Glutathione (GSH) is a major antioxidant in cells, and plays vital roles in the cellular defense against oxidants and in the regulation of redox signals. In a previous report, we... -
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- Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD
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Lee YK, Ju JM, Shon WJ, Oh S, Min CK, Kang MS, Shin DM, Choi EY
- KMID: 2429836
- Immune Netw.
- 2018 Dec;18(6):e44.
- doi: 10.4110/in.2018.18.e44
Graft-versus-host disease (GVHD), a life-threatening complication after bone marrow transplantation (BMT), is induced by activation of alloreactive donor T cells. Our previous study demonstrated that transplantation of myeloid differentiation factor... -
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- Increased store-operated Ca²⺠entry mediated by GNB5 and STIM1
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Kang N, Kang JY, Park S, Shin DM
- KMID: 2410098
- Korean J Physiol Pharmacol.
- 2018 May;22(3):343-348.
- doi: 10.4196/kjpp.2018.22.3.343
Recent human genetic studies have shown that Gβ5 is related to various clinical symptoms, such as sinus bradycardia, cognitive disability, and attention deficit hyperactivity disorder. Although the calcium signaling cascade... -
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- Comparative Evaluation of the Loop-Mediated Isothermal Amplification Assay for Detecting Pulmonary Tuberculosis
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Kim CK, Cho EA, Shin DM, Choi SW, Shin SY
- KMID: 2403356
- Ann Lab Med.
- 2018 Mar;38(2):119-124.
- doi: 10.3343/alm.2018.38.2.119
BACKGROUND: Early detection of tuberculosis (TB) is challenging in resource-poor settings because of limited accessibility to molecular diagnostics. The aim of this study was to evaluate the performance of the... -
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- The Therapeutic Effect of Human Embryonic Stem Cell-Derived Multipotent Mesenchymal Stem Cells on Chemical-Induced Cystitis in Rats
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Lee SW, Ryu CM, Shin JH, Choi D, Kim A, Yu HY, Han JY, Lee HY, Lim J, Kim YH, Heo J, Lee S, Ju H, Kim S, Hong KS, Han JY, Song M, Chung HM, Kim JK, Shin DM, Choo MS
- KMID: 2405270
- Int Neurourol J.
- 2018 Jan;22(Suppl 1):S34-S45.
- doi: 10.5213/inj.1836014.007
PURPOSE: To evaluate the therapeutic effect of human embryonic stem cell (hESC)-derived multipotent mesenchymal stem cells (M-MSCs) on ketamine-induced cystitis (KC) in rats. METHODS: To induce KC, 10-week-old female rats were... -
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- Adipose stem cell-derived nanovesicles inhibit emphysema primarily via an FGF2-dependent pathway
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Kim YS, Kim JY, Cho R, Shin DM, Lee SW, Oh YM
- KMID: 2367530
- Exp Mol Med.
- 2017 Jan;49(1):e284.
- doi: 10.1038/emm.2016.127
Cell therapy using stem cells has produced therapeutic benefits in animal models of COPD. Secretory mediators are proposed as one mechanism for stem cell effects because very few stem cells... -
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- Protective effect of dietary chitosan on cadmium accumulation in rats
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Kim MY, Shon WJ, Park MN, Lee YS, Shin DM
- KMID: 2313896
- Nutr Res Pract.
- 2016 Feb;10(1):19-25.
- doi: 10.4162/nrp.2016.10.1.19
BACKGROUND/OBJECTIVES: Cadmium is a toxic metal that is an occupational and environmental concern especially because of its human carcinogenicity; it induces serious adverse effects in various organs and tissues. Even... -
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- Prevention and Decontamination of Chemical, Biological, Radiological, and Nuclear Contaminants for the Emergency Medical Personnel during Ambulance Services
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Shin DM
- KMID: 2168360
- Hanyang Med Rev.
- 2015 Aug;35(3):146-151.
- doi: 10.7599/hmr.2015.35.3.146
This paper will review proper protocol for Emergency Medical Technicians (EMTs) between the ambulance station, scene and hospital. EMTs must know how to protect themselves both inside and outside the... -
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- Bacterial PAMPs and Allergens Trigger Increase in [Ca2+]i-induced Cytokine Expression in Human PDL Fibroblasts
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Son GY, Shin DM, Hong JH
- KMID: 1791432
- Korean J Physiol Pharmacol.
- 2015 May;19(3):291-297.
- doi: 10.4196/kjpp.2015.19.3.291
An oral environment is constantly exposed to environmental factors and microorganisms. The periodontal ligament (PDL) fibroblasts within this environment are subject to bacterial infection and allergic reaction. However, how these... -
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- Ca2+ is a Regulator of the WNK/OSR1/NKCC Pathway in a Human Salivary Gland Cell Line
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Park S, Ku SK, Ji HW, Choi JH, Shin DM
- KMID: 1791426
- Korean J Physiol Pharmacol.
- 2015 May;19(3):249-255.
- doi: 10.4196/kjpp.2015.19.3.249
Wnk kinase maintains cell volume, regulating various transporters such as sodium-chloride cotransporter, potassium-chloride cotransporter, and sodium-potassium-chloride cotransporter 1 (NKCC1) through the phosphorylation of oxidative stress responsive kinase 1 (OSR1) and... -
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- House Dust Mite Extract Induces PLC/IP3-dependent Ca2+ Signaling and IL-8 Expression in Human Gingival Epithelial Cells
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Son GY, Son A, Park W, Shin DM
- KMID: 1789364
- Int J Oral Biol.
- 2015 Mar;40(1):11-17.
- doi: 10.11620/IJOB.2015.40.1.011
The gingival epithelium of the oral cavity is constantly exposed to exogenous stimuli such as bacterial toxins, allergens, and thermal changes. These exogenous stimuli are resisted by innate host defense... -
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- Peptidoglycan Induces the Production of Interleukin-8 via Calcium Signaling in Human Gingival Epithelium
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Son A, Shin DM, Hong JH
- KMID: 2071819
- Korean J Physiol Pharmacol.
- 2015 Jan;19(1):51-57.
- doi: 10.4196/kjpp.2015.19.1.51
The etiology of periodontal disease is multifactorial. Exogenous stimuli such as bacterial pathogens can interact with toll-like receptors to activate intracellular calcium signaling in gingival epithelium and other tissues. The... -
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- Heme-binding-mediated negative regulation of the tryptophan metabolic enzyme indoleamine 2,3-dioxygenase 1 (IDO1) by IDO2
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Lee YK, Lee HB, Shin DM, Kang MJ, Yi EC, Noh S, Lee J, Lee C, Min CK, Choi EY
- KMID: 2155386
- Exp Mol Med.
- 2014 Nov;46(11):e121.
- doi: 10.1038/emm.2014.69
Indoleamine 2,3-dioxygenases (IDOs) are tryptophan-catabolizing enzymes with immunomodulatory functions. However, the biological role of IDO2 and its relationship with IDO1 are unknown. To assess the relationship between IDO2 and IDO1,... -
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