- Neoadjuvant chemotherapy followed by fertility-sparing surgery for women with stage IB1 cervical cancer
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Wang D, Yang J, Shen K, Xiang Y
- KMID: 2288537
- J Gynecol Oncol.
- 2013 Jul;24(3):287-290.
- doi: 10.3802/jgo.2013.24.3.287
Fertility-sparing surgery was optimal to patients with tumor diameter smaller than 2 cm. For patients with larger tumors, neoadjuvant chemotherapy can debulk the tumor and offer the chance of surgery.... -
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- Canonical Transient Receptor Potential Channels and Their Link with Cardio/Cerebro-Vascular Diseases
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Xiao X, Liu HX, Shen K, Cao W, Li XQ
- KMID: 2389378
- Biomol Ther.
- 2017 Sep;25(5):471-481.
- doi: 10.4062/biomolther.2016.096
The canonical transient receptor potential channels (TRPCs) constitute a series of nonselective cation channels with variable degrees of Ca2+ selectivity. TRPCs consist of seven mammalian members, TRPC1, TRPC2, TRPC3, TRPC4,... -
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- Total postoperative opioid dose is an independent risk factor for prolonged postoperative ileus after laparoscopic colorectal surgery: a case-control study
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Ju H, Shen K, Li J, Feng Y
- KMID: 2551490
- Korean J Anesthesiol.
- 2024 Feb;77(1):133-138.
- doi: 10.4097/kja.22792
Background: Prolonged postoperative ileus (PPOI) is a major complication of colorectal surgery. Increased opioid consumption has been proposed to increase the risk of PPOI. This study aimed to test the... -
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- Impact of Prior Cancer History on the Clinical Outcomes in AdvancedBreast Cancer: A Propensity Score–Adjusted, Population-Based Study
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Lin C, Wu J, Ding S, Goh C, Andriani L, Shen K, Zhu L
- KMID: 2500340
- Cancer Res Treat.
- 2020 Apr;52(2):552-562.
- doi: 10.4143/crt.2019.210
Purpose Despite the rapid growing of cancer survivors, prior cancer history is a commonly adopted exclusion criterion. Whether prior cancer will impact the survival of patients with advanced breast cancer (ABC) remains uncertain. Materials... -
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- Completion hysterectomy after chemoradiotherapy for locally advanced adeno-type cervical carcinoma: updated survival outcomes and experience in post radiation surgery
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Yang J, Yang J, Cao D, Shen K, Ma J, Zhang F
- KMID: 2470869
- J Gynecol Oncol.
- 2020 Mar;31(2):e16.
- doi: 10.3802/jgo.2020.31.e16
OBJECTIVE: To compare patient survival outcomes between completion hysterectomy and conventional surveillance in locally advanced adenocarcinoma of the cervix after concurrent chemoradiotherapy (CCRT). METHODS: Patients with adenocarcinoma of the cervix after... -
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- Extrafascial hysterectomy after concurrent chemoradiotherapy in locally advanced cervical adenocarcinoma
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Yang J, Shen K, Wang J, Yang J, Cao D
- KMID: 2374242
- J Gynecol Oncol.
- 2016 Jul;27(4):e40.
- doi: 10.3802/jgo.2016.27.e40
OBJECTIVE: To evaluate whether adjuvant simple hysterectomy after concurrent chemoradiotherapy (CCRT) improves progression-free survival (PFS) compared with current standard care in locally advanced cervical adenocarcinoma (LACAC). METHODS: We reviewed a cohort... -
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- Tailored therapy and long-term surveillance of malignant germ cell tumors in the female genital system: 10-year experience
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Zhao Q, Yang J, Cao D, Han J, Xu K, Liu Y, Shen K
- KMID: 2363320
- J Gynecol Oncol.
- 2016 May;27(3):e26.
- doi: 10.3802/jgo.2016.27.e26
OBJECTIVE: To explore the appropriate treatment of malignant germ cell tumor (MGCT) in the female genital system, and to analyze the factors influencing both therapeutic response and survival outcome. METHODS: A... -
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- Long Noncoding RNA Signature and Disease Outcome in Estrogen Receptor-Positive Breast Cancer Patients Treated with Tamoxifen
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Wang G, Chen X, Liang Y, Wang W, Fang Y, Shen K
- KMID: 2421368
- J Breast Cancer.
- 2018 Sep;21(3):277-287.
- doi: 10.4048/jbc.2018.21.e39
PURPOSE: Recent data have shown that the expression levels of long noncoding RNAs (lncRNAs) are associated with tamoxifen sensitivity in estrogen receptor (ER)-positive breast cancer. Herein, we constructed an lncRNA-based... -
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- Analysis of treatment modalities and prognosis on microinvasive cervical cancer: a 10-year cohort study in China
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Qian Q, Yang J, Cao D, You Y, Chen J, Shen K
- KMID: 2130117
- J Gynecol Oncol.
- 2014 Oct;25(4):293-300.
- doi: 10.3802/jgo.2014.25.4.293
OBJECTIVE: To explore appropriate treatment modality of microinvasive cervical cancer (MIC) and to analyze prognosis and risk factors of recurrence. METHODS: A cohort of 324 Chinese patients with MIC diagnosed and... -
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- Changes of Tumor Infiltrating Lymphocytes after Core Needle Biopsy and the Prognostic Implications in Early Stage Breast Cancer: A Retrospective Study
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Huang J, Chen X, Fei X, Huang O, Wu J, Zhu L, He J, Chen W, Li Y, Shen K
- KMID: 2460583
- Cancer Res Treat.
- 2019 Oct;51(4):1336-1346.
- doi: 10.4143/crt.2018.504
PURPOSE: The purpose of this study was to investigate the changes of tumor infiltrating lymphocytes (TILs) between core needle biopsy (CNB) and surgery removed sample (SRS) in early stage breast... -
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- Comparison of the Distribution Pattern of 21-Gene Recurrence Score between Mucinous Breast Cancer and Infiltrating Ductal Carcinoma in Chinese Population: A Retrospective Single-Center Study
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Wu J, Ding S, Lin L, Fei X, Lin C, Andriani L, Goh C, Huang J, Hong J, Gao W, Zhu S, Wang H, Huang O, Chen X, He J, Li Y, Shen K, Chen W, Zhu L
- KMID: 2504449
- Cancer Res Treat.
- 2020 Jul;52(3):671-679.
- doi: 10.4143/crt.2019.387
Purpose This retrospective study aimed to evaluate the distribution pattern and prognostic value of 21-gene recurrence score (RS) in Chinese patients with mucinous breast cancer (MC) and compared with infiltrating ductal... -
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- Weight Gain during Neoadjuvant Chemotherapy is Associated with Worse Outcome among the Patients with Operable Breast Cancer
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Fang Q, Huang J, Gan L, Shen K, Chen X, Wu B
- KMID: 2458861
- J Breast Cancer.
- 2019 Sep;22(3):399-411.
- doi: 10.4048/jbc.2019.22.e37
PURPOSE: This study was aimed at identifying the influence of initial weight and weight change during neoadjuvant chemotherapy (NAC) on pathologic complete response (pCR) and long-term survival in Chinese patients... -
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- Germline and somatic mutations in homologous recombination genes among Chinese ovarian cancer patients detected using next-generation sequencing
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Zhao Q, Yang J, Li L, Cao D, Yu M, Shen K, the BGI Group
- KMID: 2413427
- J Gynecol Oncol.
- 2017 Jul;28(4):e39.
- doi: 10.3802/jgo.2017.28.e39
OBJECTIVE: To define genetic profiling of homologous recombination (HR) deficiency in Chinese ovarian cancer patients. METHODS: we have applied next-generation sequencing to detect deleterious mutations through all exons in 31 core... -
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