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Evaluation of circulating IGF-I and IGFBP-3 as biomarkers for tumors in dogs

Song DW, Ro WB, Sur JH, Seung BJ, Kang HM, Kim JW, Park SH, Park HM

Background: Serum-based parameters are considered non-invasive biomarkers for cancer detection. In human studies, insulin-like growth factor-I and II (IGF-I and IGF-II) and insulin-like growth factor binding protein-3 (IGFBP-3) are useful...
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Differential and correlated expressions of p16/p21/p27/p38 in mammary gland tumors of aged dogs

Kim HW, Ju JH, Shin JI, Seung BJ, Sur JH

The inhibitory effect of neutering on mammary gland tumor development in dogs has been well described. However, we observed that the effect of neutering on tumor malignancy may be altered...
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Arginase-1 and P-glycoprotein are downregulated in canine hepatocellular carcinoma

Kim SH, Seung BJ, Cho SH, Lim HY, Bae MK, Sur JH

Background Hepatocellular carcinoma is the most common primary hepatic malignancy in humans and dogs. Several differentially expressed molecules have been studied and reported in human hepatocellular carcinoma and non-neoplastic liver lesions....
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Classification, bacteriological findings, and analysis of sex hormone receptors and cytokine expression in mammary lesions of abattoir sows

Ju JH, Shin JI, Lim HY, Kim HW, Seung BJ, Cho SH, Kim SH, Sur JH

Mammary lesions in sows can prevent suckling piglets from consuming colostrum that provides fundamental nutrients and protective immunity. Although mammary gross lesions are frequently found in sows at farms or...
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