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A Simple and Fast Web Alignment Tool for Large Amount of Sequence Data

Lee YS, Oh J

  • KMID: 2166414
  • Genomics Inform.
  • 2008 Sep;6(3):157-159.
Multiple sequence alignment (MSA) is the most important step for many of biological sequence analyses, homology search, and protein structural assignments. However, large amount of data make biologists difficult to perform...
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Sequence Analysis and Potential Action of Eukaryotic Type Protein Kinase from Streptomyces coelicolor A3(2)

Roy DR, Chandra SB

  • KMID: 2166321
  • Genomics Inform.
  • 2008 Mar;6(1):44-49.
Protein kinase C (PKC) is a family of kinases involved in the transduction of cellular signals that promote lipid hydrolysis. PKC plays a pivotal role in mediating cellular responses to...
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A Primer for Disease Gene Prioritization Using Next-Generation Sequencing Data

Wang S, Xing J

High-throughput next-generation sequencing (NGS) technology produces a tremendous amount of raw sequence data. The challenges for researchers are to process the raw data, to map the sequences to genome, to...
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Functional Role of a Conserved Sequence Motif in the Oxygen-dependent Degradation Domain of Hypoxia-inducible Factor 1 alpha in the Recognition of p53

Chi SW

  • KMID: 2166342
  • Genomics Inform.
  • 2008 Jun;6(2):72-76.
Hypoxia-inducible factor 1 alpha (HIF1 alpha) is a transcription factor that plays a key role in the adaptation of cells to low oxygen stress and oxygen homeostasis. The oxygen-dependent degradation...
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A Simple Java Sequence Alignment Editing Tool for Resolving Complex Repeat Regions

Ham SI, Lee KE, Park HS

  • KMID: 2166442
  • Genomics Inform.
  • 2009 Mar;7(1):46-48.
Finishing is the most time-consuming step in sequencing, and many genome projects are left unfinished due to complex repeat regions. Here, we have developed BACContigEditor, a prototype shotgun sequence finishing...
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Cloning and characterization of a selenium-independent glutathione peroxidase (HC29) from adult Haemonchus contortus

Sun W, Song X, Yan R, Xu L, Li X

The complete coding sequence of Haemonchus (H.) contortus HC29 cDNA was generated by rapid amplification of cDNA ends in combination with PCR using primers targeting the 5'- and 3'-ends of...
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BioCovi: A Visualization Service for Comparative Genomics Analysis

Lee J, Park D, Bhak J

  • KMID: 1572632
  • Genomics Inform.
  • 2005 Jun;3(2):52-54.
Visualization of the homology information is an important method to analyze the evolutionary and functional meanings of genes. With a database containing model genomes of Homo sapiens, Mus muculus, and...
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Cloning a new allele form of bovine TNF-alpha

Ahn J

  • KMID: 1103522
  • J Vet Sci.
  • 2001 Aug;2(2):139-141.
Although little is known on the function of gammadelta T lymphocytes, there is increasing evidence that gammadelta T lymphocytes are early responders and modulators of immune responses against pathogens and...
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Sequence Variation in Superoxide Dismutase Gene of Toxoplasma gondii among Various Isolates from Different Hosts and Geographical Regions

Wang S, Cao A, Li X, Zhao Q, Liu Y, Cong H, He S, Zhou H

Toxoplasma gondii, an obligate intracellular protozoan parasite of the phylum Apicomplexa, can infect all warm-blooded vertebrates, including humans, livestock, and marine mammals. The aim of this study was to investigate...
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Molecular cloning of the cDNA of canine homeodomain-interacting protein kinase 2

Lee SY, Chung JY, Shin IS, Choi EW, Hwang CY, Youn HY, Han HR

  • KMID: 1114855
  • J Vet Sci.
  • 2005 Jun;6(2):141-145.
The research of p53 is being conducted to find the mechanisms of tumorigenesis and to treat various cancers. Homeodomain-interacting protein kinase2 (HIPK2) is an important factor to regulate p53 and...
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Comparative Genomics Study of Interferon-alpha Receptor-1 in Humans and Chimpanzees

Kim IC, Chi SW, Kim DW, Choi SH, Chae SH, Park HS

  • KMID: 2284673
  • Genomics Inform.
  • 2005 Dec;3(4):142-148.
The immune response-related genes have been suggested to be the most favorable genes for positive selection during evolution. Comparing the entire DNA sequence of chimpanzee chromosome 22 (PTR22) with human...
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Retrotransposon Microsatellite Amplified Polymorphism Strain Fingerprinting Markers Applicable to Various Mushroom Species

Le QV, Won HK, Lee TS, Lee CY, Lee HS, Ro HS

The retrotransposon marY1 is a gypsy family retroelement, which is detected ubiquitously within the fungal taxonomic groups in which mushrooms are included. To utilize marY1 as a molecular marker for...
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Haplotype Phylogeny of a 200kb Region in the Human Chromosome X Terminal Band (q28)

Kim S

  • KMID: 2166409
  • Genomics Inform.
  • 2008 Sep;6(3):130-135.
The haplotypes of a 200 kb region in the human chromosome X terminal band (q28) were analyzed using the International HapMap Project PhaseII data, which had been collected for three...
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Sequence analysis of canine LINE-1 elements and p53 gene in canine transmissible venereal tumor

Choi YK, Kim CJ

  • KMID: 1097345
  • J Vet Sci.
  • 2002 Dec;3(4):285-292.
LINEs (long interspersed nuclear elements or long interspersed repeated DNA elements) contains two open reading frames (ORFs), ORF1 and ORF2. We analysed the ORF2 located in the 5' region to...
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Cloning of BNIP3h, a member of proapoptotic BNIP3 family genes

Farooq M, Kim YH, Im SU, Chung EJ, Hwang SY, Sohn MY, Kim MK, Kim JC

  • KMID: 938882
  • Exp Mol Med.
  • 2001 Sep;33(3):169-173.
Apoptosis is regulated by interaction of antiapoptotic Bcl-2 family proteins with various proapoptotic proteins, several of which are also members of the Bcl-2 family. BNIP3 (formerly NIP3) is a proapoptotic...
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Variation of nuclear and mitochondrial DNAs in Korean and Chinese isolates of Clonorchis sinensis

Lee SU, Huh S

We compared the DNA sequence difference of isolates of Clonorchis sinensis from one Korean (Kimhae) and two Chinese areas (Guangxi and Shenyang). The sequences of nuclear rDNA (18S, internal transcribed...
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Primary structure of mature SAG1 gene of an Indonesian Toxoplasma gondii and comparison with other strains

Hartati S, Kusumawati A, Wuryastuti H, Widada JS

Toxoplasma gondii is a persistent protozoan parasite capable of infecting almost any warm-blooded vertebrates. SAG1 (p30) is the prototypic member of a superfamily of surface antigens called SRS (SAG1-related sequence)....
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Genetic characterization of porcine circovirus-2 field isolates from PMWS pigs

Kim JH, Lyoo YS

  • KMID: 1101572
  • J Vet Sci.
  • 2002 Mar;3(1):31-39.
PMWS is a new emerging disease in swine herds worldwide. Field isolates of PCV-2, a putative major causative agent of PMWS, were isolated and genetically characterized. Viral genome of two...
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Molecular cloning of ribosomal P protein in Toxoplasma gondii and the availability to detect antibody against recombinant protein in toxoplasmosis patients

Ahn HJ, Kim S, Nam HW

Among the panel of monoclonal antibodies (mAb) against Toxoplasma gondii, mAb of Tg621 (Tg621) clone blotted 38 kDa protein which localized in the cytoplasm of tachyzoites by immunofluorescence microscopy. The...
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Molecular characterization and phylogenetic analysis of pseudorabies virus variants isolated from Guangdong province of southern China during 2013–2014

Fan J, Zeng X, Zhang G, Wu Q, Niu J, Sun B, Xie Q, Ma J

Outbreaks of pseudorabies (PR) have occurred in southern China since late 2011, resulting in significant economic impacts on the swine industry. To identify the cause of PR outbreaks, especially among...
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