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Analysis of Discrepancies Between G-banding and FISH in Hematologic Abnormalities

Lee DY, See CJ, Hwang CD, Cho HI, Lee DS

  • KMID: 2089678
  • Korean J Clin Pathol.
  • 2001 Dec;21(6):445-450.
BACKGROUND: The effective treatment of hematologic malignancies depends upon application of different therapeutic strategies by selecting patients known as the high risk group and the detection of malignant cells that...
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Comparison of the Rate of Detection of Immunoglobulin Heavy Chain Gene Rearrangement by Fluoresecence In Situ Hybridization Probes in Multiple Myeloma

Chung HY, See CJ, Choi JE, Min HJ, Cho HI, Lee DS

BACKGROUND: Immunoglobulin heavy chain (IgH) gene rearrangement, which is frequently observed in multiple myeloma, can now be detected easily by using a fluorescence in situ hybridization (FISH) method. The aim...
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Why Should FISH Be Done in Patients with Acute Leukemias to Detect MLL Translocation?

Kim HJ, Lee DS, See CJ, Ko EK, Shin HY, Ahn HS, Park SY, Kim BK, Cho HI

  • KMID: 2146098
  • Korean J Clin Pathol.
  • 2001 Oct;21(5):315-322.
BACKGROUND: Translocations involving the MLL gene on the long arm of chromosome 11 (11q23) are frequently observed in acute leukemia. The detection of this genetic change has a unique significance...
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The incidence of ABL Deletion on Derivative 9 Chromosome in Chronic Myelogenous Leukemia by Interphase Fluorescence In Situ Hybridization and its Association with Progression to Blast Crisis

Jeong S, Lee DS, See CJ, Ko EK, Park S, Cho HI

  • KMID: 2225972
  • Korean J Clin Pathol.
  • 2000 Dec;20(6):521-526.
BACKGROUND: Philadelphia(Ph) chromosome is found in about 95 percent of chronic myelogenous leukemia(CML) patients. Ph chromosome results from a reciprocal translocation between the long arms of chromosomes 9 and 22,...
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The application of an in situ karyotyping technique for mesenchymal stromal cells: a validation and comparison study with classical G-banding

Hwang SM, See CJ, Choi J, Kim SY, Choi Q, Kim JA, Kwon J, Park SN, Im K, Oh IH, Lee DS

  • KMID: 2154287
  • Exp Mol Med.
  • 2013 Dec;45(12):e68.
The cytogenetic analysis of mesenchymal stromal cells (MSCs) is essential for verifying the safety and stability of MSCs. An in situ technique, which uses cells grown on coverslips for karyotyping...
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Dysregulation of Telomere Lengths and Telomerase Activity in Myelodysplastic Syndrome

Park HS, Choi J, See CJ, Kim JA, Park SN, Im K, Kim SM, Lee DS, Hwang SM

BACKGROUND: Telomere shortening is thought to be involved in the pathophysiology of myeloid malignancies, but telomere lengths (TL) during interphase and metaphase in hematopoietic malignancies have not been analyzed. We...
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