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Effects of Compounds from Physalis angulata on Fatty Acid Synthesis and Glucose Metabolism in HepG2 Cells via the AMP-activated Protein Kinase Pathway

Hoa HT, Thu NT, Dong NT, Oanh TT, Hien TT, Ha DT

The ability of the total extract from Physalis angulata; three fractions after partitioning with n-hexane, ethyl acetate (TBE), and water; and four withanolides (compounds 1 – 4) to phosphorylate 5'-adenosine...
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The effects of black garlic (Allium satvium) extracts on lipid metabolism in rats fed a high fat diet

Ha AW, Ying T, Kim WK

BACKGROUD/OBEJECTIVES: The mechanism of how black garlic effects lipid metabolism remains unsolved. Therefore, the objectives of this study were to determine the effects of black garlic on lipid profiles and...
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Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1

Jung YA, Kim HK, Bae KH, Seo HY, Kim HS, Jang BK, Jung GS, Lee IK, Kim MK, Park KG

Hepatic steatosis is common in obese individuals with hyperinsulinemia and is an important hepatic manifestation of metabolic syndrome. Sterol regulatory binding protein-1c (SREBP-1c) is a master regulator of lipogenic gene...
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The effect of fucoxanthin rich power on the lipid metabolism in rats with a high fat diet

Ha AW, Kim WK

  • KMID: 2313682
  • Nutr Res Pract.
  • 2013 Aug;7(4):287-293.
This study determined the effects of fucoxanthin on gene expressions related to lipid metabolism in rats with a high-fat diet. Rats were fed with normal fat diet (NF, 7% fat)...
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Effects of Alpha-lipoic Acid on SREBP-1c Expression in HepG2 Cells

Yun TS, Min AK, Kim NK, Kim MK, Cho HC, Kim HS, Hwang JS, Ryu SY, Park KG, Lee IK

BACKGROUND: Non-alcoholic fatty liver disease is common in patients with insulin resistance. Sterol regulatory element binding protein-1c (SREBP-1c) is a member of a family of transcription factors that have been...
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