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Abuse Potential of Synthetic Cannabinoids: AM-1248, CB-13, and PB-22

Hur KH, Ma SX, Lee BR, Ko YH, Seo JY, Ryu HW, Kim HJ, Yoon S, Lee YS, Lee SY, Jang CG

Currently, the expanding recreational use of synthetic cannabinoids (SCBs) threatens public health. SCBs produce psychoactive effects similar to those of tetrahydrocannabinol, the main component of cannabis, and additionally induce unexpected...
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Comparison of the new and conventional injury severity scoring systems for predicting mortality in severe geriatric trauma

Ryu HW, Ahn JY, Seo KS, Park JB, Kim JK, Lee MJ, Ryoo HW, Kim YJ, Kim C, Choe JY, Lee DE, Yeo IH, Moon S, Cho Y, Chung HS, Cho JW, Jung H

  • KMID: 2511367
  • J Korean Soc Emerg Med.
  • 2020 Dec;31(6):543-552.
Objective: This study compared the prognostic performance of the following five injury severity scores: the Geriatric Trauma Outcome Score (GTOS), the Injury Severity Score (ISS), the New Injury Severity Score...
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Short Course and Early Switch of Vigabatrin for Infantile spasms

Ryu HW, Kim H, Lim BC, Hwang H, Chae JH, Choi JE, Kim KJ

Purpose: Vigabatrin has proven efficacy in the treatment of infantile spasms, but it carries the risk of irreversible visual field constriction. The incidence of vigabatrin-induced visual field constriction seems to...
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Artemisia argyi attenuates airway inflammation in lipopolysaccharide induced acute lung injury model

Shin NR, Park SH, Ko JW, Ryu HW, Jeong SH, Kim JC, Shin DH, Lee HS, Shin IS

Artemisia argyi is used as a health supplement, tea, and food source in Korea. This study aimed to evaluate the effect of Artemisia argyi (AA) and its active compound, dehydromatricarin...
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The Efficacy and Safety of Platinum/Vinorelbine as More Than Second-Line Chemotherapy for Advanced Non-small Cell Lung Cancer

Song IC, Lee HJ, Yang YJ, Choi YS, Ryu HW, Lee MW, Moon JY, Jo DY, Kim S, Yun HJ

PURPOSE: There is no regimen that is strongly recommended for more than second-line treatment. We investigated the efficacy and safety of platinum/vinorelbine as more than second-line treatment. MATERIALS AND METHODS: We...
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Anti-herpes Activity of Vinegar-processed Daphne genkwa Flos Via Enhancement of Natural Killer Cell Activity

Uyangaa E, Choi JY, Ryu HW, Oh SR, Eo SK

Herpes simplex virus (HSV) is a common causative agent of genital ulceration and can lead to subsequent neurological disease in some cases. Here, using a genital infection model, we tested...
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Weber-Cockayne Type Epidermolysis Bullosa Simplex Resulting from a Novel Mutation (c. 608T>C) in the Keratin 5 Gene

Cho JW, Ryu HW, Kim SA, Nakano H, Lee KS

Epidermolysis bullosa simplex (EBS), an inherited genetic disorder, is most often caused by a dominant-negative mutation in either the keratin 5 (KRT5) or the keratin 14 (KRT14) gene. These keratin...
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Anti-Inflammatory Effect of Mangostenone F in Lipopolysaccharide-Stimulated RAW264.7 Macrophages by Suppressing NF-kappaB and MAPK Activation

Cho BO, Ryu HW, So Y, Lee CW, Jin CH, Yook HS, Jeong YW, Park JC, Jeong IY

  • KMID: 2170621
  • Biomol Ther.
  • 2014 Jul;22(4):288-294.
Mangostenone F (MF) is a natural xanthone isolated from Garcinia mangostana. However, little is known about the biological activities of MF. This study was designed to investigate the anti-inflammatory effect...
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Electroencephalographic Features of Rasmussen's Encephalitis by Stage

Ryu HW, Yoo IH, Kim H, Lim BC, Hwang H, Chae JH, Choi J, Kim KJ, Hwang YS

  • KMID: 2329259
  • J Korean Child Neurol Soc.
  • 2014 Jun;22(2):52-57.
PURPOSE: The purpose of this study was to describe the characteristic electroencephalographic features in Rasmussen's encephalitis by stage. METHODS: Patients diagnosed with Rasmussen's encephalitis at Seoul National University Children's Hospital were...
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Efficacy and Tolerability of Valproic Acid Once Daily Dosing for Juvenile Myoclonic Epilepsy

Choi SA, Kim SY, Yoo IH, Ryu HW, Kim H, Lim BC, Hwang H, Chae JH, Choi J, Kim KJ, Hwang YS

  • KMID: 2329258
  • J Korean Child Neurol Soc.
  • 2014 Jun;22(2):47-51.
PURPOSE: The purpose of this study was to evaluate the efficacy and tolerability of extended-release valproic acid once daily dosing in juvenile myoclonic epilepsy (JME). METHODS: Medical records of patients who...
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Anti-fibrotic Effect of Silibinin in Keloid Fibroblasts and a Bleomycin-induced, Scleroderma-like Animal Model

Ryu HW, Kim SP, Cho JW, Lee KS

  • KMID: 1732320
  • Korean J Dermatol.
  • 2014 Jun;52(6):373-380.
BACKGROUND: Silibinin reduces the expression of Type I collagen in normal skin fibroblasts through down-regulation of the TGF-beta/smad pathway. However, it is largely unknown whether silibinin can reduce the expression...
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Blood lead levels of Korean lead workers in 2003-2011

Kim JH, Kim EA, Koh DH, Byun K, Ryu HW, Lee SG

OBJECTIVES: This study aimed to document the trend in blood lead levels in Korean lead workers from 2003 until 2011 and blood lead levels within each of the main industries. METHODS:...
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Effectiveness and Tolerability of Fosphenytoin for Pediatric Status Epilepticus

Hong WG, Yoo IH, Kim JS, Ryu HW, Byun SH, Kim H, Lim BC, Chae JH, Choi J, Kim KJ, Hwang YS, Hwang H

  • KMID: 2329619
  • J Korean Child Neurol Soc.
  • 2013 Mar;21(1):1-6.
PURPOSE: The study was aimed to investigate the effectiveness and tolerability of intravenous fosphenytoin (fPHT) in the treatment of pediatric status epilepticus (SE). METHODS: Medical-records of patients who received intravenous (IV)...
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Lupus Profundus with Segmental Distribution on Leg, Following the Lines of Blaschko in a Child

Ryu HW, Lee KS, Cho JW

  • KMID: 2088663
  • Korean J Dermatol.
  • 2013 Feb;51(2):148-150.
Lupus profundus is a rare subtype of chronic cutaneous lupus erythematosus, which shows a tender subcutaneous nodule or plaque. The face, arm, buttock, trunk and thighs are frequently involved. Lupus...
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Clinical Characteristics of Post-traumatic Seizures in Children

Kim JS, Ryu HW, Byun SH, Kim H, Lim BC, Chae JH, Choi J, Kim KJ, Hwang YS, Hwang H

  • KMID: 1425840
  • J Korean Child Neurol Soc.
  • 2012 Dec;20(4):228-233.
PURPOSE: Post-traumatic seizures (PTS) are well-recognized complications from head injuries and children are particularly more vulnerable to them. The aim of this study was to investigate the clinical characteristics of...
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A case of Becker muscular dystrophy with early manifestation of cardiomyopathy

Doo KH, Ryu HW, Kim SS, Lim BC, Hwang H, Kim KJ, Hwang YS, Chae JH

An 18-year-old boy was admitted with chest discomfort, nausea, and dyspnea at rest. At the age of 3 years, he underwent muscle biopsy and dystrophin gene analysis owing to an...
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Efficacy and Tolerability of Rufinamide for Intractable Generalized Epilepsies

Yoo IH, Hong WG, Kim JS, Ryu HW, Byun SH, Kim H, Lim BC, Chae JH, Choi J, Kim KJ, Hwang YS, Hwang H

  • KMID: 2059497
  • J Korean Child Neurol Soc.
  • 2012 Sep;20(3):164-169.
PURPOSE: The purpose of the study was to evaluate the efficacy and safety of rufinamide for intractable generalized epilepsies. METHODS: Eighteen patients with intractable generalized epilepsies were included in the study....
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Pityriasis Versicolor on Penile Shaft in a Renal Transplant Recipient

Ryu HW, Cho JW, Lee KS

Pityriasis versicolor is a superficial infection of the stratum corneum, which is caused by the Malassezia species. Tge Malassezia species consist of 12 subspecies, including M. furfur, M. pachydermatis, M....
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Primary Cutaneous Nocardiosis with Sporotrichoid Pattern by N. brasiliensis in Lung Cancer Patient

Ryu HW, Lee KS, Rhyoo NH, Cho JW

  • KMID: 2247463
  • Korean J Dermatol.
  • 2012 May;50(5):468-471.
Nocardia is aerobic gram positive bacteria, which is found in the soil. Cutaneous nocardiosis is divided into the primary skin infection and secondary infection due to systemic dissemination from the...
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Curcumin Induced Decreased Expression of Type I Collagen in Human Skin Fibroblast Through Down-regulation of Smad2/3 Expressions

Ryu HW, Kim SP, Lee KS, Cho JW

  • KMID: 2247498
  • Korean J Dermatol.
  • 2012 Jan;50(1):1-7.
BACKGROUND: Imbalance among TGF-beta/Smad pathway, MMP-1, and TIMP-1 expressions results in sclerotic skin disease, such as scleroderma, hypertrophic scar, and keloids. Curcumin, a phytochemical extracted from the rhizomes of Curcuma...
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