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Vitamin D and Male Fertility: An Updated Review

Cito G, Cocci A, Micelli E, Gabutti A, Russo GI, Coccia ME, Franco G, Serni S, Carini M, Natali A

To date, the key role of vitamin D in male reproductive system has been suggested, since the expression of vitamin D receptors and metabolizing enzymes was demonstrated in the testis...
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A comprehensive review and the pharmacologic management of primary dysmenorrhea

Lee D, Kim SK

Dysmenorrhea is the most common gynecologic condition in women during the reproductive period. Severe dysmenorrhea pain affects their social activities, sleep, and quality of life. Nevertheless, the proportion of women...
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The treatment of an edentulous patient with conventional complete denture and CAD/CAM complete denture

Cho S, Lee J

In patients with fully edentulous jaw, treatment of complete dentures should be carried out in many stages when following the conventional methods. Therefore there were disadvantages such as multiple visits...
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Establishment of NOAEL for intracavernous injections of human bone marrow-derived mesenchymal stem cells in rats

Kim JK, Jang MJ, Kim BH, Choi KR, Song G, Shin HC, Suh N, Kim YM, You D, Ahn TY, Kim CS

PURPOSE: To assess the possible negative health effects of human bone marrow-derived mesenchymal stem cells (hBMSCs) on fertility and early embryonic development following intracavernous injections in rats. MATERIALS AND METHODS: A...
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Effect of melatonin on the onset of puberty in male juvenile rats

Venugopal

Melatonin or N-acetyl-5-methoxytryptamine, the fascinating molecule secreted by the pineal gland. Melatonin has a close interaction with hypothalamic-pituitary-gonadal axis. In non-seasonal breeders like rat its exact role in reproduction is...
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From papyrus leaves to bioprinting and virtual reality: history and innovation in anatomy

Bisht B, Hope A, Paul MK

The human quest to master the anatomy and physiology of living systems started as early as 1600 BC, with documents from the Greeks, Indians, and Romans presenting the earliest systematic...
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Fertility outcome after medically treated pyometra in dogs

Melandri M, Veronesi M, Pisu MC, Majolino G, Alonge S

Cystic endometrial hyperplasia-pyometra complex (CEH/P) is a challenge in canine reproduction. Present study aimed to assess fertility after medical treatment. One-hundred-seventy-four bitches affected by CEH/P received aglepristone on days 1,...
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Poorly-Controlled Type 1 Diabetes Mellitus Impairs LH-LHCGR Signaling in the Ovaries and Decreases Female Fertility in Mice

Lee J, Lee HC, Kim SY, Cho GJ, Woodruff T

PURPOSE: The aim of this study was to investigate how type I diabetes mellitus (T1D) affects the folliculogenesis and oocyte development, fertilization, and embryo development. MATERIALS AND METHODS: A comparative animal...
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Differential gene expression analysis of human cumulus cells

Demiray SB, Goker EN, Tavmergen , Yilmaz O, Calimlioglu N, Soykam HO, Oktem G, Sezerman U

OBJECTIVE: This study was performed to explore the possibility that each oocyte and its surrounding cumulus cells might have different genetic expression patterns that could affect human reproduction. METHODS: Differential gene...
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Early-life exposure to endocrine-disrupting chemicals and pubertal development in girls

Lee JE, Jung HW, Lee YJ, Lee YA

Over the last decades, the onset of puberty in girls has occurred earlier, but the tempo of pubertal progression has been relatively slower, resulting in a younger age at puberty...
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Data Fitting and Scenario Analysis of Vaccination in the 2014 Ebola Outbreak in Liberia

Xie Z

OBJECTIVES: This study aimed to extend an epidemiological model (SEIHFR) to analyze epidemic trends, and evaluate intervention efficacy. METHODS: SEIHFR was modified to examine disease transmission dynamics after vaccination for the...
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C-Type Natriuretic Peptide/Natriuretic Peptide Receptor 2 Is Involved in Cell Proliferation and Testosterone Production in Mouse Leydig Cells

Yang L, Lei L, Zhao Q, Gong Y, Guan G, Huang S

PURPOSE: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secretion in mouse Leydig cells. MATERIALS AND METHODS: Mouse testis of different postnatal stages...
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Metabolic Syndrome and Male Fertility

Martins AD, Majzoub A, Agawal A

Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global...
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A New Metabolic Network Correlated with Olfactory and Executive Dysfunctions in Idiopathic Rapid Eye Movement Sleep Behavior Disorder

Yoon EJ, Lee JY, Nam H, Kim HJ, Jeon B, Jeong JM, Kim YK

BACKGROUND AND PURPOSE: To identify a metabolic network reflecting neurodegeneration in patients with idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD). METHODS: We recruited a prospective cohort comprising patients with...
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Combined biomarker for prediction of response to an immune checkpoint inhibitor in metastatic gastric cancer

Heo YJ, Kang SY, Kim ST, Kang WK, Lee J, Kim KM

PURPOSE: Immune checkpoint blockades (ICB) have been successful in gastric cancer (GC). However, the majority of unselected patients with GC fail to respond to ICB. It is crucial to identify...
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Conserved Roles of MonA in Fungal Growth and Development in Aspergillus Species

Son YE, Park HS

MonA is a subunit of a guanine nucleotide exchange factor that is important for vacuole passing and autophagy processes in eukaryotes. In this study, we characterized the function of MonA,...
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Partial Characterization of Two Cathepsin D Family Aspartic Peptidases of Clonorchis sinensis

Kang JM, Yoo WG, Lê HG, Thái TL, Hong SJ, Sohn WM, Na BK

Cathepsin D (CatD, EC 3.4.23.5) is a member belonging to the subfamily of aspartic endopeptidases, which are classified into the MEROPS clan AA, family A1. Helminth parasites express a large...
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Evaluation of the immunobiological effects of a regenerative far-infrared heating system in pigs

Kim S, Park HT, Soh SH, Oh MW, Shim S, Yoo HS

Thermal conditions are an important environmental factor in maintaining healthy pigs because they affect feed intake, growth efficiency, reproduction and immune responses in pigs. RAVI, a regenerative far-infrared heating system,...
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Health Indicators Related to Disease, Death, and Reproduction

Choi J, Ki M, Kwon HJ, Park B, Bae S, Oh CM, Chun BC, Oh GJ, Lee YH, Lee TY, Cheong HK, Choi BY, Park JH, Park SK

One of the primary goals of epidemiology is to quantify various aspects of a population’s health, illness, and death status and the determinants (or risk factors) thereof by calculating health...
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Modification of the Conventional Influenza Epidemic Models Using Environmental Parameters in Iran

Naserpor A, Niakan Kalhori SR, Ghazisaeedi M, Azizi R, Hosseini Ravandi M, Sharafie S

OBJECTIVES: The association between the spread of infectious diseases and climate parameters has been widely studied in recent decades. In this paper, we formulate, exploit, and compare three variations of...
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