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How important is dietary management in chronic kidney disease progression? A role for low protein diets

Ko GJ, Kalantar-Zadeh K

High dietary protein intake may lead to increased intraglomerular pressure and glomerular hyperfiltration, which in the long-term can lead to de novo or aggravating preexisting chronic kidney disease (CKD). Hence,...
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Blood pressure control in patients with chronic kidney disease

Lee JY, Han SH

Uncontrolled blood pressure (BP) in patients with chronic kidney disease (CKD) can lead to serious adverse outcomes. To prevent the occurrence of cardiovascular events (CVEs), and end-stage kidney disease, achieving...
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Risk Factors for Chronic Kidney Disease in Pediatric Patients with Epilepsy

Pak J, Byeon JH, Yim CH, Eun BL

Purpose: The aim of the treatment of epileptic seizures is to achieve a seizure-free state without adverse effects. The mainstays of seizure treatment are anticonvulsant medication, diet therapy, and surgery....
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Renal safety and urate-lowering efficacy of febuxostat in gout patients with stage 4–5 chronic kidney disease not yet on dialysis

Kim SH, Lee SY, Kim JM, Son CN

Background/Aims: The safety and efficacy of febuxostat in patients with stage 4–5 chronic kidney disease (CKD) are still unclear owing to a lack of studies in these patients. Therefore, we...
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Association between Hypothyroidism and Chronic Kidney Disease in Korean Adults: A Study Based on the Sixth Korea National Health and Nutrition Examination Survey (KNHANES VI), 2013–2015

Jang SY, Yang YS, Yoon J, Yun JM, Bae WK, Kim CY, Kim JY, Lee K

Background: Previous studies suggested the correlation between thyroid and kidney functions, especially the high prevalence of hypothyroidism in chronic kidney disease. This study aimed to evaluate the influence of hypothyroidism...
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The clinical impact of gut microbiota in chronic kidney disease

Kim SM, Song Ih

Gut microorganisms play critical roles in both maintaining host homeostasis and the development of diverse diseases. Gut dysbiosis, an alteration of the composition and function of gut microorganisms, is commonly...
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More evidence that direct acting antiviral therapy is safe and effective in cirrhosis and chronic kidney disease including peritoneal dialysis

Kwo P, Dronamraju D

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Supplementary nutrients for prevention of vascular calcification in patients with chronic kidney disease

Lee SM, An WS

Vascular calcification (VC) and malnutrition associated with cardiovascular disease are common in patients with chronic kidney disease (CKD) treated with dialysis. VC, which reflects vascular aging, and malnutrition are also...
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The role of oxidative stress and hypoxia in renal disease

Honda T, Hirakawa Y, Nangaku M

Oxygen is required to sustain aerobic organisms. Reactive oxygen species (ROS) are constantly released during mitochondrial oxygen consumption for energy production. Any imbalance between ROS production and its scavenger system...
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Klotho and Postmenopausal Hormone Replacement Therapy in Women with Chronic Kidney Disease

Park YJ, Kim JM

Kidney function is highly susceptible to age-related changes, with chronic kidney disease (CKD) serving as an important cause of morbidity and mortality in older patients. The prevalence of CKD in...
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Metabolic syndrome: prevalence and risk factors in Korean gout patients

Jung JH, Song GG, Ji JD, Lee YH, Kim JH, Seo YH, Choi SJ

BACKGROUND/AIMS: We performed this study to investigate associations between metabolic syndrome, chronic kidney disease (CKD), and gout. METHODS: We reviewed the medical records of 151 patients with gout at the Department...
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Chronic kidney disease in the BCR-ABL1-negative myeloproliferative neoplasm: a single-center retrospective study

Baek SW, Moon JY, Ryu H, Choi YS, Song IC, Lee HJ, Yun HJ, Kim S, Jo DY

BACKGROUND/AIMS: Renal complications related to BCR-ABL1-negative myeloproliferative neoplasms (MPNs) have not been examined fully in Asian populations. METHODS: We analyzed estimated glomerular filtration rate (eGFR) and its changes with time retrospectively...
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Hepatitis C virus infection in chronic kidney disease: paradigm shift in management

Kim SM, Song IH

Hepatitis C virus (HCV) infection in chronic kidney disease (CKD) is associated with increased liver-related morbidity and mortality rates, accelerated progression to end-stage renal disease, and risk of cardiovascular events....
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Higher Prevalence and Progression Rate of Chronic Kidney Disease in Elderly Patients with Type 2 Diabetes Mellitus

Kim KS, Park SW, Cho YW, Kim SK

BACKGROUND: To evaluate the prevalence of chronic kidney disease (CKD) and progression rate to CKD in elderly patients with type 2 diabetes mellitus (T2DM). METHODS: We investigated the medical records of...
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Number of existing permanent teeth is associated with chronic kidney disease in the elderly Korean population

Shin HS

BACKGROUND/AIMS: The aim of this study was to assess the association between the number of existing permanent teeth and chronic kidney disease (CKD) in a representative sample of the elderly...
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Clinical significance of renal cortical thickness in patients with chronic kidney disease

Korkmaz M, Aras B, Güneyli S, Yılmaz M

PURPOSE: The aim of this study was to evaluate the correlations between laboratory findings and ultrasonographic measurements of renal length and cortical thickness in patients receiving follow-up for chronic kidney...
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Low serum bilirubin level predicts the development of chronic kidney disease in patients with type 2 diabetes mellitus

Ahn KH, Kim SS, Kim WJ, Kim JH, Nam YJ, Park SB, Jeon YK, Kim BH, Kim IJ, Kim YK

BACKGROUND/AIMS: We evaluated whether serum bilirubin levels can predict the development of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM). METHODS: This was a retrospective observational longitudinal...
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Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes

Han E, Kim G, Lee JY, Lee YH, Kim BS, Lee BW, Cha BS, Kang ES

BACKGROUND: Although the beneficial effects of statin treatment in dyslipidemia and atherosclerosis have been well studied, there is limited information regarding the renal effects of statins in diabetic nephropathy. We...
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Sleep duration and chronic kidney disease: The Korean Genome and Epidemiology Study (KoGES)-Kangwha study

Choi H, Kim HC, Lee JY, Lee JM, Choi DP, Suh I

BACKGROUND/AIMS: Sleep duration affects health in various ways. The objective of this study was to investigate the associations of sleep duration with chronic kidney disease (CKD) in a Korean adult...
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Eligibility for Statin Treatment in Korean Subjects with Reduced Renal Function: An Observational Study

Moon BS, Kim J, Kim JH, Hyun YY, Park SE, Oh HG, Park CY, Lee WY, Oh KW, Lee KB, Kim H, Park SW, Rhee EJ

BACKGROUND: The purpose of this study was to investigate the relationship between statin eligibility and the degree of renal dysfunction using the Adult Treatment Panel (ATP) III and the American...
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