- The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least
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Cai J, Wang F, Shao M
- KMID: 2546980
- Endocrinol Metab.
- 2023 Oct;38(5):493-503.
- doi: 10.3803/EnM.2023.1813
The growing recognition of mitochondria’s crucial role in the regulation of white adipose tissue remodeling and energy balance underscores its significance. The marked metabolic diversity of mitochondria provides the molecular... -
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- Losartan Reduces Remodeling and Apoptosis in an Adriamycin-Induced Cardiomyopathy Rat Model
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Kim HA, Kim KC, Lee H, Hong YM
- KMID: 2545973
- J Chest Surg.
- 2023 Sep;56(5):295-303.
- doi: 10.5090/jcs.23.044
Background: The use of Adriamycin (ADR), also known as doxorubicin, as a chemotherapy agent is limited by its detrimental adverse effects, especially cardiotoxicity. Recent studies have emphasized the crucial role... -
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- Clinical efficacy of angiotensin receptor-neprilysin inhibitor in de novo heart failure with reduced ejection fraction
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Park SY, Kong MG, Moon I, Park HW, Choi HO, Seo HS, Cho YH, Lee NH, Lee KY, Jang HJ, Kim JS, Choi IJ, Suh J
- KMID: 2545694
- Korean J Intern Med.
- 2023 Sep;38(5):692-703.
- doi: 10.3904/kjim.2023.065
Background/Aims: We aimed to analyze the efficacy of angiotensin receptor-neprilysin inhibitor (ARNI) by the disease course of heart failure (HF). Methods: We evaluated 227 patients with HF in a multi-center retrospective... -
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- Non-Contrast Cine Cardiac Magnetic Resonance Derived-Radiomics for the Prediction of Left Ventricular Adverse Remodeling in Patients With ST-Segment Elevation Myocardial Infarction
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A X, Liu M, Chen T, Chen F, Qian G, Zhang Y, Chen Y
- KMID: 2545509
- Korean J Radiol.
- 2023 Sep;24(9):827-837.
- doi: 10.3348/kjr.2023.0061
Objective: To investigate the predictive value of radiomics features based on cardiac magnetic resonance (CMR) cine images for left ventricular adverse remodeling (LVAR) after acute ST-segment elevation myocardial infarction (STEMI). Materials... -
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- Development of Matrix Metalloproteinases-Mediated Extracellular Matrix Remodeling in Regenerative Medicine: A Mini Review
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Chen K, Xu M, Lu F, He Y
- KMID: 2545045
- Tissue Eng Regen Med.
- 2023 Aug;20(5):661-670.
- doi: 10.1007/s13770-023-00536-x
Extracellular matrix (ECM) components confer biomechanical properties, maintain cell phenotype and mediate tissue homeostasis. ECM remodeling is complex and plays a key role in both physiological and pathological processes. Matrix... -
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- Computational Analysis of miR-140 and miR-135 as Potential Targets to Develop Combinatorial Therapeutics for Degenerative Tendinopathy
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Morya VK, Lee HW, Park CW, Park CW, Hyun JT, Noh KC
- KMID: 2542327
- Clin Orthop Surg.
- 2023 Jun;15(3):463-476.
- doi: 10.4055/cios22237
Background: Degenerative tendinopathy, a condition causing movement restriction due to high pain, highly impacts productivity and quality of life. The healing process is a complex phenomenon and involves a series... -
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- Remodeling and Restraining Lung Tissue Damage Through the Regulation of Respiratory Immune Responses
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Pyung YJ, Park DJ, Kim CG, Yun CH
- KMID: 2542955
- Tissue Eng Regen Med.
- 2023 Jun;20(3):329-339.
- doi: 10.1007/s13770-022-00516-7
Tissue damage caused by various stimuli under certain conditions, such as biological and environmental cues, can actively induce systemic and/or local immune responses. Therefore, understanding the immunological perspective would be... -
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- A Vitronectin-Derived Peptide Restores Ovariectomy-Induced Bone Loss by Dual Regulation of Bone Remodeling
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Kang HK, Park CY, Jung SY, Jo SB, Min BM
- KMID: 2536464
- Tissue Eng Regen Med.
- 2022 Dec;19(6):1359-1376.
- doi: 10.1007/s13770-022-00486-w
BACKGROUND: Bone remodeling is tightly regulated through bone resorption and bone formation; imbalances in bone remodeling can cause various pathological conditions such as osteoporosis. Antiresorptive agents commonly used for treating... -
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- Real-World Usage of Sacubitril/ Valsartan in Korea: A Multi-Center, Retrospective Study
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Park JJ, Lee SE, Cho HJ, Choi JO, Yoo BS, Kang SM, Wang HC, Lee S, Choi DJ
- KMID: 2536295
- Int J Heart Fail.
- 2022 Oct;4(4):193-204.
- doi: 10.36628/ijhf.2022.0015
Background and Objectives: Differences in drug prescriptions exist between clinical trials and real-world practice. We evaluated the real-world treatment patterns of sacubitril/ valsartan in Korean patients with heart failure (HF). Methods:... -
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- Independent Skeletal Actions of Pituitary Hormones
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Kim SM, Sultana F, Korkmaz F, Lizneva D, Yuen T, Zaidi M
- KMID: 2534624
- Endocrinol Metab.
- 2022 Oct;37(5):719-731.
- doi: 10.3803/EnM.2022.1573
Over the past years, pituitary hormones and their receptors have been shown to have non-traditional actions that allow them to bypass the hypothalamus-pituitary-effector glands axis. Bone cells—osteoblasts and osteoclasts—express receptors... -
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- Pharmacological Approaches to Limit Ischemic and Reperfusion Injuries of the Heart: Analysis of Experimental and Clinical Data on P2Y 12 Receptor Antagonists
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Maslov LN, Popov SV, Mukhomedzyanov AV, Derkachev IA, Ryabov VV, Boshchenko AA, Prasad NR, Sufianova GZ, Khlestkina MS, Gareev I
- KMID: 2534038
- Korean Circ J.
- 2022 Oct;52(10):737-754.
- doi: 10.4070/kcj.2022.0162
Ischemic and reperfusion injuries of the heart underlie the pathogenesis of acute myocardial infarction (AMI) and sudden cardiac death. The mortality rate is still high and is 5–7% in patients... -
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- Extra Cellular Matrix Remodeling: An Adjunctive Target for Spinal Cord Injury and Intervertebral Disc Degeneration
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Kumar A, Kumar N, Pathak Z, Kumar H
- KMID: 2533791
- Neurospine.
- 2022 Sep;19(3):632-645.
- doi: 10.14245/ns.2244366.183
The extracellular matrix (ECM) is a protein-and-carbohydrate meshwork that supports a variety of biological structures and processes, from tissue development and elasticity to the preservation of organ structures. ECM composition... -
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- Assessment of left atrial remodeling using speckle tracking echocardiography after percutaneous atrial septal defect closure in adult patients
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Choi J, Kim J, Hwang J, Kim H, Chung T, Kim J, Park S, Kang I, Song J, Park S, Park K, On Y, Kim J, Huh J
- KMID: 2534097
- Int J Arrhythm.
- 2022 Sep;23(3):23.
- doi: 10.1186/s42444-022-00074-y
Background: Atrial fibrillation (AF) is a well-known, long-term complication of atrial septal defect (ASD) in adults, even after device closure. Left atrial (LA) strain rate applied to the analysis of... -
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- HMGB1 increases RAGE expression in vascular smooth muscle cells via ERK and p-38 MAPK-dependent pathways
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Jang EJ, Kim H, Baek SE, Jeon EY, Kim JW, Kim JY, Kim CD
- KMID: 2532768
- Korean J Physiol Pharmacol.
- 2022 Sep;26(5):389-396.
- doi: 10.4196/kjpp.2022.26.5.389
The increased expression of receptors for advanced glycation endproduct (RAGE) is known as a key player in the progression of vascular remodeling. However, the precise signal pathways regulating RAGE expression in... -
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- Biomechanical evaluations of the long-term stability of dental implant using finite element modeling method: a systematic review
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Hosseini-Faradonbeh SA, Katoozian HR
- KMID: 2531070
- J Adv Prosthodont.
- 2022 Jun;14(3):182-202.
- doi: 10.4047/jap.2022.14.3.182
PURPOSE The aim of this study is to summarize various biomechanical aspects in evaluating the long-term stability of dental implants based on finite element method (FEM). MATERIALS AND METHODS A comprehensive search was... -
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- Effects of Combination Oral Contraceptives on Bone Mineral Density and Metabolism in Perimenopausal Korean Women
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Kim SM, Shin W, Kim HJ, Lee JS, Min YK, Yoon BK
- KMID: 2529882
- J Menopausal Med.
- 2022 Apr;28(1):25-32.
- doi: 10.6118/jmm.21027
Objectives: A retrospective cohort study was conducted to evaluate the effects of combination oral contraceptives (COCs) on bone mineral density (BMD) and metabolism in perimenopausal Korean women. Methods: The study subjects... -
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- Pore and Acne Scar Treatment with a Q-switched Laser Using a Novel Fractional MDF (Multi-depth Focusing) Handpiece: A Pilot Study
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Park J, Lee H, Hwang JK
- KMID: 2533543
- Med Lasers.
- 2022 Mar;11(1):31-39.
- doi: 10.25289/ML.2022.11.1.31
Background and Objectives Although skin rejuvenation is not within the usual repertoire of the Q-switched 1064 nm Nd:YAG (Q-NDY) laser, the development of a multidepth focusing (MDF) handpiece allowing user-selectable depths... -
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- Establishment of a murine model based on chronic exposure to domestic house dust mites in Korea
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Lee SH, Chang WS, Jeong KT, Lee JK
- KMID: 2525462
- Allergy Asthma Respir Dis.
- 2022 Jan;10(1):22-32.
- doi: 10.4168/aard.2022.10.1.22
Purpose: Asthma is a chronic disorder characterized by bronchial hyperresponsiveness and reversible airflow obstruction. Repeated exposure to allergens of the respiratory tract causes chronic inflammation, followed by structural changes in... -
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- SGLT2 Inhibitors and Ketone Metabolism in Heart Failure
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Saucedo-Orozco H, Voorrips SN, Yurista SR, de Boer RA, Westenbrink BD
- KMID: 2525232
- J Lipid Atheroscler.
- 2022 Jan;11(1):1-19.
- doi: 10.12997/jla.2022.11.1.1
Sodium-glucose cotransporter-2 (SGLT2) inhibitors have emerged as powerful drugs that can be used to treat heart failure (HF) patients, both with preserved and reduced ejection fraction and in the presence... -
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- Bone Healing in Adolescents with Bilateral L5 Spondylolysis with and without Preexisting Contralateral Terminal Spondylolysis
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Eto F, Tatsumura M, Gamada H, Okuwaki S, Koda M, Yamazaki M
- KMID: 2523374
- Asian Spine J.
- 2021 Dec;15(6):747-752.
- doi: 10.31616/asj.2020.0309
Study Design: Retrospective cohort study. Purpose: To examine bone healing with conservative treatment in cases of adolescent bilateral L5 spondylolysis. Overview of Literature: We classified bilateral L5 spondylolysis, which is the most... -
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