- The reno-protective effect of a phosphoinositide 3-kinase inhibitor wortmannin on streptozotocin-induced proteinuric renal disease rats
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Kim SH, Jang YW, Hwang P, Kim HJ, Han GY, Kim CW
- KMID: 1120141
- Exp Mol Med.
- 2012 Jan;44(1):45-51.
- doi: 10.3858/emm.2012.44.1.004
Diabetic nephropathy (DN) is a progressive kidney disease that is caused by injury to kidney glomeruli. Podocytes are glomerular epithelial cells and play critical roles in the glomerular filtration barrier.... -
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- Isolation of rice allergenic cDNA clones from a rice cDNA library by immunoscreening with a polyclonal antibody specific to 16 kD rice allergenic protein
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Kim NI, Kim WC, Lee SM, Lee HK, Rhee HI, Choi YS, Jung YH, Cha SH
- KMID: 1029925
- Exp Mol Med.
- 1999 Dec;31(4):185-190.
Clinical cases of type-1 hypersensitive reaction to rice (Oryza sativa) have been reported in western countries as well as in Japan. Among rice proteins, 14-16 kD globulin proteins... -
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- Effect of ceramide on apoptosis and phospholipase D activity in FRTL-5 thyroid cells
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Park BJ, Kim JH, Han JS, Jung PM
- KMID: 755043
- Exp Mol Med.
- 1999 Sep;31(3):142-150.
Ceramide, a product of sphingomyelin hydrolysis, is now recognized as an intracellular lipid messenger, which mediates the effects of extracellular agents on cellular growth, differentiation and apoptosis. Recently, ceramide has been implicated in... -
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- Morphologic studies of the retina in a new diabetic model; SHR/N:Mcc-cp rat
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Kim SH, Chu YK, Kwon OW, McCune SA, Davidorf F
- KMID: 711583
- Yonsei Med J.
- 1998 Oct;39(5):453-462.
- doi: 10.3349/ymj.1998.39.5.453
The pathogenesis of diabetic retinopathy has not been fully explained. The earliest histological lesion is the loss of intramural pericytes and thickening of the basement membrane. Increased activity of the... -
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- Histopathologic changes of the spleen in suckling rats inoculated with Hantaan virus
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Cho HJ, Paek LJ, Lee HW
- KMID: 1421900
- J Korean Med Sci.
- 1992 Jun;7(2):116-121.
- doi: 10.3346/jkms.1992.7.2.116
The purpose of this study is to delineate the histopathologic findings of the spleen after Hantaan viral inoculation, which is the largest lymphoid organ in rats, and to identify... -
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- Isolation and cultivation of microvascular endothelial cells from rat lungs: effects of gelatin substratum and serum
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Kim NS, Kim SJ
- KMID: 1057639
- Yonsei Med J.
- 1991 Dec;32(4):303-314.
- doi: 10.3349/ymj.1991.32.4.303
Microvascular endothelial cells from rat lungs were cultured in serum-free medium supplemented with an endothelial growth substance, insulin, hydrocortisone and so on. Five to seven days after plating, cultured cells... -
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- Scanning electron microscopic study of capillary change in bleomycin-induced pulmonary fibrosis
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Kwon KY, Park KK, Chang ES
- KMID: 1421860
- J Korean Med Sci.
- 1991 Sep;6(3):234-245.
- doi: 10.3346/jkms.1991.6.3.234
The architectural changes which occur in the capillaries are difficult to illustrate without a three-dimensional tool, such as scanning electron microscopy. Therefore, a scanning electron microscopic study was occasionally undertaken... -
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- Homologous fibronectin enhances healing of excised wounds in rats
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Jo JS, Hong SB, Shin HI, Choi JJ
- KMID: 1421856
- J Korean Med Sci.
- 1991 Sep;6(3):197-205.
- doi: 10.3346/jkms.1991.6.3.197
In order to evaluate the effects of a topical application of homologous fibronectin on the healing of skin wounds, we made 2 excisional wounds on the back skin of each... -
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- Neoplastic Paneth cells in the experimental murine carcinoma of the small intestine
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Kim WH, Kim YI
- KMID: 1421501
- J Korean Med Sci.
- 1990 Dec;5(4):197-203.
- doi: 10.3346/jkms.1990.5.4.197
The purpose of this study is to elucidate the participation of Paneth cells in experimentally induced adenocarcinoma of the intestine. The rats were fed with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) dissolved in drinking... -
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- Studies on rat liver nuclear DNA damaged by chemical carcinogen (3'-Me DAB) and AP DNA endonuclease. I. Purification and some properties of AP DNA endonucleases in rat liver chromatin
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Kim YS, Kim JW, Lee SE, Oh SH
- KMID: 1421490
- J Korean Med Sci.
- 1990 Sep;5(3):127-135.
- doi: 10.3346/jkms.1990.5.3.127
Three kinds of apurinic/apyrimidinic (AP) DNA endonuclease, APcI, APcII, APcIII, were purified from rat liver chromatin through 1M KCl extraction, DEAE-trisacryl ion exchange chromatography. Sephadex G-150 gel filtration and AP... -
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- Comparison between electrophysiologic and morphologic changes in lead induced peripheral neuropathy in rats
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Hwang YM, Sunwoo IN, Chung IH, Jung B
- KMID: 1421469
- J Korean Med Sci.
- 1989 Dec;4(4):185-192.
- doi: 10.3346/jkms.1989.4.4.185
Compound nerve action potential (CNAP) of the mixed peripheral nerve is composed of A alpha beta, A delta, and C potentials. All components of CNAPs in the sciatic nerve were... -
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- The influence of tissue expanders on grafted vessels
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Lee SH, Hong C, Futrell JW
- KMID: 1105560
- Yonsei Med J.
- 1989 Dec;30(4):327-333.
- doi: 10.3349/ymj.1989.30.4.327
Interpositionally grafted arteries and veins were expanded with a 20cc tissue expanders in 50 Sprague-Dawley rats. The grafts were done on both hind legs, one side was expanded and... -
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- Regulation of acetyl CoA carboxylase mRNA in rat liver by high carbohydrate diet and insulin
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Choi DH, Choi JH, Whang SK, Kim YS
- KMID: 1097014
- Yonsei Med J.
- 1989 Sep;30(3):235-245.
- doi: 10.3349/ymj.1989.30.3.235
Acetyl CoA carboxylase contents in liver cytosol of rats refed a high carbohydrate diet or injected with insulin were measured by an immunoassay method in order to evaluate the... -
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- Tumor associated proteins of rat skin tumor induced by 7,12-dimethylbenz[a]anthracene
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Park KK, Kim YS
- KMID: 1097013
- Yonsei Med J.
- 1989 Sep;30(3):219-234.
- doi: 10.3349/ymj.1989.30.3.219
The incidence of tumor and the time of expression, cellular localization and the molecular weight of tumor associated proteins of rat skin tumor induced by 7,12-dimethylbenz[a]anthracene (DMBA) with or... -
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- Experimental exencephaly and myeloschisis in rats
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Hong SK, Chi JG, Sim BS
- KMID: 1421447
- J Korean Med Sci.
- 1989 Mar;4(1):35-50.
- doi: 10.3346/jkms.1989.4.1.35
To elucidate the early sequential morphogenetic progress of exencephaly and myeloschisis, rat embryos whose mothers had been treated with hypervitaminosis A were studied at 1-day interval from gestation day 10.5... -
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- Characterization of lnhibition by Nifedipine and Nitroprusside of the Pressor Respones to alpha1-Adrenoceptor Agonists Cirazoline and Sgd 101/75 in Pithed Rats
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Jung HO, Hong KW
- KMID: 1119205
- Yonsei Med J.
- 1988 Jun;29(2):176-184.
- doi: 10.3349/ymj.1988.29.2.176
In this study the effects of two unrelated vasodilators, nifedipine and nitroprusside, on the pressor responsiveness to the 1-adrenoceptor full agonist cirazoline and partial agonist Sgd 101/75 in pithed rats... -
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- Membrane Potential in Luteal Cells from Cyclic Rats: Relationship to Steroidogenic Capacity
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Kim L, Park HS, Koo BS
- KMID: 693109
- Yonsei Med J.
- 1988 Mar;29(1):29-36.
- doi: 10.3349/ymj.1988.29.1.29
To examine the electrophysiological properties of luteal cells and the relationship between membrane potential and luteal steroidogenic capacity, the membrane potential of luteal cells and the luteal steroidogenesis were measured... -
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- Characterization of Tumor Specific Antigens on the Plasma Membrane Surface of Rat Hepatomas lnduced by 3'-Me DAB and ldentification of the Common Tumor Specific Antigens from Rat Hepatomas lnduced by Different Chemical Hepatocarcinogens
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Kim YS, Hahm KS, Kim KS, Lee NJ
- KMID: 693108
- Yonsei Med J.
- 1988 Mar;29(1):17-28.
- doi: 10.3349/ymj.1988.29.1.17
Three different chemical carcinogens, 2-acetylaminofluorene (AAF), diethylnitrosamine(DENA), and 3'-methyl-4dimethylaminoazobenzene (3'-Me DAB) were used to induce hepatomas in rats. Plasma membrane surface proteins of normal rat liver cells and rat hepatomas... -
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- Factors Influencing the Pathogenicity of Entamoeba Histolytica
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Soh CT
- KMID: 693106
- Yonsei Med J.
- 1988 Mar;29(1):1-10.
- doi: 10.3349/ymj.1988.29.1.1
In summarizing the results of the experimental studies up to the present, it is conjectured that the pathogenicity of Entamoeba histolytica or establishment of amoebiasis is not unique but differs... -
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- The effect of verapamil on cysteamine-induced duodenal ulcer in the rat
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Lee CK, Yim DS, Kim WH
- KMID: 1421274
- J Korean Med Sci.
- 1987 Dec;2(4):247-253.
- doi: 10.3346/jkms.1987.2.4.247
To determine the effect of verapamil on experimental duodenal ulcer, pathologic assessment and secretory study were performed in the rats with ulcerogenic dose of cysteamine. The cysteamine increased gastric... -
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