- Metformin treatment confers protection of the optic nerve following photoreceptor degeneration
-
Eltony SA, Mohaseb HS, Sayed MM, Ahmed AA
- KMID: 2516909
- Anat Cell Biol.
- 2021 Jun;54(2):249-258.
- doi: 10.5115/acb.20.320
Acquired or inherited or photoreceptor loss causes retinal ganglion cell loss and ultimately axonal transport alteration. Thus, therapies should be applied early during photoreceptors degeneration before the remodeling process reaches... -
- CITED
-
- Close
- SHARE
-
- Close
- Growth and Differentiation of Circulating Stem Cells After Extensive Ex Vivo Expansion
-
Barbon S, Rajendran S, Bertalot T, Piccione M, Gasparella M, Parnigotto PP, Liddo RD, Conconi MT
- KMID: 2516528
- Tissue Eng Regen Med.
- 2021 Jun;18(3):411-427.
- doi: 10.1007/s13770-021-00330-7
BACKGROUND: Stem cell therapy is gaining momentum as an effective treatment strategy for degenerative diseases. Adult stem cells isolated from various sources (i.e., cord blood, bone marrow, adipose tissue) are being... -
- CITED
-
- Close
- SHARE
-
- Close
- Estrogen modulates epithelial progenitor cells in rat vagina
-
Chung HS, Lee HS, Park K
- KMID: 2515330
- Investig Clin Urol.
- 2021 May;62(3):349-353.
- doi: 10.4111/icu.20200513
Purpose: The expression of epithelial progenitor cells (EPCs) in rat vagina was recently reported. The aims were to investigate the effects of estrogen on vaginal EPCs in the oophorectomized female... -
- CITED
-
- Close
- SHARE
-
- Close
- A novel excisional wound pain model for evaluation of analgesics in rats
-
Parra S, Thanawala VJ, Rege A, Giles H
- KMID: 2514416
- Korean J Pain.
- 2021 Apr;34(2):165-175.
- doi: 10.3344/kjp.2021.34.2.165
Background: Management of pain from open wounds is a growing unmet healthcare need. However, the models available to study pain from wounds or to develop analgesics for the patients suffering... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of Intravesical Hyaluronic Acid, Chondroitin Sulfate, and Combination of Hyaluronic Acid-Chondroitin Sulfate Therapies in Animal Model of Interstitial Cystitis
-
Danacioglu YO, Erol B, Ozkanli S, Yildirim A, Atis RG, Silay MS, Caskurlu T
- KMID: 2514214
- Int Neurourol J.
- 2021 Mar;25(1):42-50.
- doi: 10.5213/inj.1938176.088
Purpose: Three intravesical treatment agents were compared in an interstitial cystitis rat model: chondroitin sulfate, hyaluronic acid, and combined hyaluronic acid-chondroitin sulfate. Methods: Thirty-five female rats were divided into 5 groups:... -
- CITED
-
- Close
- SHARE
-
- Close
- Tail suspension is useful as a sarcopenia model in rats
-
Nemoto A, Goyagi T
- KMID: 2514397
- Lab Anim Res.
- 2021 Mar;37(1):60-66.
- doi: 10.1186/s42826-020-00083-9
Background Sarcopenia promotes skeletal muscle atrophy and exhibits a high mortality rate. Its elucidation is of the highest clinical importance, but an animal experimental model remains controversial. In this study, we... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of resveratrol on the inflammatory response and renal injury in hyperuricemic rats
-
Xiao B, Ma W, Zheng Y, Li Z, Li D, Zhang Y, Li Y, Wang D
- KMID: 2511671
- Nutr Res Pract.
- 2021 Feb;15(1):26-37.
- doi: 10.4162/nrp.2021.15.1.26
BACKGROUND/OBJECTIVES: Hyperuricemic nephropathy is a common cause of acute kidney injury. Resveratrol can ameliorate kidney injury, but the explicit mechanism remains unclear. We investigated the effects of resveratrol on the inflammatory... -
- CITED
-
- Close
- SHARE
-
- Close
- Human Dental Pulp Stem Cells (DPSCs) Therapy in Rescuing Photoreceptors and Establishing a Sodium Iodate-Induced Retinal Degeneration Rat Model
-
Lam C, Alsaeedi HA, Koh AEH, Harun MHN, Hwei ANM, Mok PL, Luu CD, Yong TK, Subbiah SK, Bastion MLC
- KMID: 2512646
- Tissue Eng Regen Med.
- 2021 Feb;18(1):143-154.
- doi: 10.1007/s13770-020-00312-1
BACKGROUND: Different methods have been used to inject stem cells into the eye for research. We previously explored the intravitreal route. Here, we investigate the efficacy of intravenous and subretinal-transplanted... -
- CITED
-
- Close
- SHARE
-
- Close
- Changes in Cecal Microbiota and Short-chain Fatty Acid During Lifespan of the Rat
-
Choi SI, Son JH, Kim N, Kim YS, Nam RH, Park JH, Song CH, Yu JE, Lee DH, Yoon K, Min H, Kim YR, Seok YJ
- KMID: 2510071
- J Neurogastroenterol Motil.
- 2021 Jan;27(1):134-146.
- doi: 10.5056/jnm20148
Background/Aims The gut microbiota regulates intestinal immune homeostasis through host-microbiota interactions. Multiple factors affect the gut microbiota, including age, sex, diet, and use of drugs. In addition, information on gut microbiota... -
- CITED
-
- Close
- SHARE
-
- Close
- Systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla
-
Li Y, Kang DH, Kim WM, Lee HG, Kim SH, You HE, Choi JI, Yoon MH
- KMID: 2510312
- Korean J Pain.
- 2021 Jan;34(1):58-65.
- doi: 10.3344/kjp.2021.34.1.58
Background: Supraspinal delivery of neurotensin (NTS), which may contribute to the effect of a systemically administered agonist, has been reported to be either pronociceptive or antinociceptive. Here, we evaluated the... -
- CITED
-
- Close
- SHARE
-
- Close
- The effect of adenosine triphosphate on propofol-induced myopathy in rats: a biochemical and histopathological evaluation
-
Erdem KTO, Bedir Z, Ates I, Kuyrukluyildiz U, Coban TA, Yazici GN, Arslan YK, Suleyman Z, Suleyman H
- KMID: 2509656
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):69-77.
- doi: 10.4196/kjpp.2021.25.1.69
Propofol infusion syndrome characterized by rhabdomyolysis, metabolic acidosis, kidney, and heart failure has been reported in long-term propofol use for sedation. It has been reported that intracellular adenosine triphosphate (ATP)... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of poly (ethylene glycol-propylene glycol) copolymer on hemostasis and osteogenesis in a rat calvarial defect model
-
Kim HE, Yoon HY, Kim EJ, Kim SJ
- KMID: 2507023
- Korean J Vet Res.
- 2020 Sep;60(3):145-153.
- doi: 10.14405/kjvr.2020.60.3.145
Abstract: This study aimed to evaluate the effects of a bioabsorbable bone hemostatic agent comprising poly (ethylene glycolpropylene glycol) copolymers (PEG-PPG) on hemostasis and osteogenesis. Bilateral 3 mm diameter calvarial... -
- CITED
-
- Close
- SHARE
-
- Close
- In vivo quantification of mandibular bone remodeling and vascular changes in a Wistar rat model: A novel HR-MRI and micro-CT fusion technique
-
Song D, Shujaat S, Zhao R, Huang Y, Shaheen E, Dessel JV, Orhan K, Velde GV, Coropciuc R, Pauwels R, Politis C, Jacobs R
- KMID: 2506604
- Imaging Sci Dent.
- 2020 Sep;50(3):199-208.
- doi: 10.5624/isd.2020.50.3.199
Purpose: This study was performed to introduce an in vivo hybrid multimodality technique involving the coregistration of micro-computed tomography (micro-CT) and high-resolution magnetic resonance imaging (HR-MRI) to concomitantly visualize and... -
- CITED
-
- Close
- SHARE
-
- Close
- Activation of AMPK by Telmisartan Decreases Basal and PDGF-stimulated VSMC Proliferation via Inhibiting the mTOR/p70S6K Signaling Axis
-
Hwang YJ, Park JH, Cho DH
- KMID: 2506085
- J Korean Med Sci.
- 2020 Sep;35(35):e289.
- doi: 10.3346/jkms.2020.35.e289
Background: Telmisartan, an angiotensin II type 1 receptor blocker (ARB), is widely used to treat hypertension by blocking the renin-angiotensin-aldosterone system. Although abnormal proliferation of vascular smooth muscle cells (VSMCs)... -
- CITED
-
- Close
- SHARE
-
- Close
- An Optimization of AAV-82Q-Delivered Rat Model of Huntington’s Disease
-
So KH, Choi JH, Islam J, KC E, Moon HC, Won SY, Kim HK, Kim S, Hyun SH, Park YS
- KMID: 2506021
- J Korean Neurosurg Soc.
- 2020 Sep;63(5):579-589.
- doi: 10.3340/jkns.2019.0182
Objective : No optimum genetic rat Huntington model both neuropathological using an adeno-associated virus (AAV-2) vector vector has been reported to date. We investigated whether direct infection of an AAV2... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of Optical Coherence Tomography Findings and Histological Findings of Meibomian Gland in Rats
-
Lee SH, Eom Y, Song JS, Na KS, Kim EC, Kim HS, Kim MS, Hwang HS
- KMID: 2505302
- J Korean Ophthalmol Soc.
- 2020 Aug;61(8):849-854.
- doi: 10.3341/jkos.2020.61.8.849
Purpose: To compare optical coherence tomography (OCT) and histological findings of Meibomian glands in rats. Based onthese results, the histological findings of the structures seen using OCT were clarified. Methods: En... -
- CITED
-
- Close
- SHARE
-
- Close
- Protective and Therapeutic Effects of Aloe Vera Gel on Ulcerative Colitis Induced by Acetic Acid in Rats
-
Bahrami G, Malekshahi H, Miraghaee S, Madani H, Babaei A, Mohammadi B, Hatami R
- KMID: 2512192
- Clin Nutr Res.
- 2020 Jul;9(3):223-234.
- doi: 10.7762/cnr.2020.9.3.223
Ulcerative colitis (UC) is a chronic intestinal inflammation. Common clinical symptoms are weight loss, diarrhea, ulcers, and inflammation. Aloe vera (AV) has several medicinal properties including antioxidant, anti-inflammatory analgesic, and... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparative study of acute in vitro and short-term in vivo triiodothyronine treatments on the contractile activity of isolated rat thoracic aortas
-
López RM, López JS, Lozano J, Flores H, Carranza RA, Franco A, Castillo EF
- KMID: 2503327
- Korean J Physiol Pharmacol.
- 2020 Jul;24(4):339-348.
- doi: 10.4196/kjpp.2020.24.4.339
We aimed to characterize the participation of rapid non-genomic and delayed non-genomic/genomic or genomic mechanisms in vasoactive effects to triiodothyronine (T3), emphasizing functional analysis of the involvement of these mechanisms... -
- CITED
-
- Close
- SHARE
-
- Close
- Pim-1 Protects Retinal Ganglion Cells by Enhancing Their Regenerative Ability Following Optic Nerve Crush
-
Zhang S, Shuai L, Wang D, Huang T, Yang S, Miao M, Liu F, Xu J
- KMID: 2503984
- Exp Neurobiol.
- 2020 Jun;29(3):249-272.
- doi: 10.5607/en20019
Provirus integration site Moloney murine leukemia virus (Pim-1) is a proto-oncogene reported to be associated with cell proliferation, differentiation and survival. This study was to explore the neuroprotective role of... -
- CITED
-
- Close
- SHARE
-
- Close
- Aster ageratoides Turcz. extract attenuates Alzheimer’s disease-associated cognitive deficits and vascular dementia-associated neuronal death
-
Jeong JH, Lee SE, Lee JH, Kim HD, Seo KH, Kim DH, Han SY
- KMID: 2503451
- Anat Cell Biol.
- 2020 Jun;53(2):216-227.
- doi: 10.5115/acb.20.011
Dementia is the common neurodegenerative disorder affecting the elderly, with a progressive cognitive decline and memory loss. Since Alzheimer’s disease (AD) and vascular dementia (VD) share key pathologies including oxidative... -
- CITED
-
- Close
- SHARE
-
- Close
