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Novel biological strategies to enhance the radiation therapeutic ratio

Kim JH, Jenrow KA, Brown SL

Successful anticancer strategies require a differential response between tumor and normal tissue (i.e., a therapeutic ratio). In fact, improving the effectiveness of a cancer therapeutic is of no clinical value...
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Impact of testicular shielding in liposarcoma to scrotum by using radio-photoluminescence glass dosimeter (RPLGD): a case report

Oonsiri P, Saksornchai K, Suriyapee

Radiation protection in the scrotum to reduce the risk of genetic effect in the future is very important. This study aimed to measure the scrotal dose outside the treatment fields...
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Evaluation of the hybrid-dynamic conformal arc therapy technique for radiotherapy of lung cancer

Kim SJ, Lee JW, Kang MK, Kim JC, Lee JE, Park SH, Kim MY, Lee SJ, Moon SH, Ko BS

PURPOSE: A hybrid-dynamic conformal arc therapy (HDCAT) technique consisting of a single half-rotated dynamic conformal arc beam and static field-in-field beams in two directions was designed and evaluated in terms...
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Dose comparison between prescription methods according to anatomical variations in intracavitary brachytherapy for cervical cancer

Choi E, Kim JH, Kim OB, Byun SJ, Kim JH, Oh YK

PURPOSE: We compared how doses delivered via two-dimensional (2D) intracavitary brachytherapy (ICBT) and three-dimensional (3D) ICBT varied anatomically. MATERIALS AND METHODS: A total of 50 patients who received 30 Gy of...
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Assessment of inter- and intra-fractional volume of bladder and body contour by mega-voltage computed tomography in helical tomotherapy for pelvic malignancy

Kim S, You SH, Eum YJ

PURPOSE: We describe the daily bladder volume change observed by mega-voltage computed tomography (MVCT) during pelvic radiotherapy with potential predictors of increased bladder volume variations. MATERIALS AND METHODS: For 41 patients...
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Single nucleotide polymorphism of GSTP1 and pathological complete response in locally advanced rectal cancer patients treated with neoadjuvant concomitant radiochemotherapy

Nicosia L, Gentile G, Reverberi , Minniti G, Valeriani , de Sanctis V, Marinelli , Cipolla F, de Luca O, Simmaco M, Osti MF

PURPOSE: Standard treatment for locally advanced rectal cancer consists of neoadjuvant radiochemotherapy with concomitant fluoropyrimidine or oxaliplatin and surgery with curative intent. Pathological complete response has shown to be predictive...
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Optimal timing for salvage surgery after definitive radiotherapy in hypopharyngeal cancer

Chun SJ, Keam B, Heo DS, Kim KH, Sung MW, Chung EJ, Kim JH, Jung KC, Kim JH, Wu HG

PURPOSE: Use of radiotherapy combined with chemotherapy is increasing in hypopharyngeal cancer. However, many show residual tumor after radiotherapy. Timing for treatment evaluation and salvage therapy is essential. However, optimal...
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Use of radiotherapy in patients with palliative double bypass for locally advanced pancreatic adenocarcinoma

Glinka J, Diaz F, Alva A, Mazza O, Sanchez Claria R, Ardiles V, de Santibañes E, Pekolj J, de Santibañes M

PURPOSE: Pancreatic cancer (PC) has not changed overall survival in recent years despite therapeutic efforts. Surgery with curative intent has shown the best long-term oncological results. However, 80%–85% of patients...
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Clinical outcome of proton therapy for patients with chordomas

Youn SH, Cho KH, Kim JY, Ha B, Lim YK, Jeong JH, Lee SH, Yoo H, Gwak HS, Shin SH, Hong EK, Kim HK, Hong JB

PURPOSE: To investigate the clinical outcome of proton therapy (PT) in patients with chordoma. MATERIALS AND METHODS: Fifty-eight patients with chordoma treated with PT between June 2007 and December 2015 at...
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Effectiveness and feasibility of concurrent chemoradiotherapy using simultaneous integrated boost-intensity modulated radiotherapy with and without induction chemotherapy for locally advanced pancreatic cancer

Oh ES, Kim TH, Woo SM, Lee WJ, Lee JH, Youn SH, Han SS, Park SJ, Kim DY

PURPOSE: To evaluate the effectiveness and feasibility of chemoradiotherapy (CRT) using simultaneous integrated boost-intensity modulated radiotherapy (SIB-IMRT) in locally advanced pancreatic cancer (LAPC) patients. MATERIALS AND METHODS: Between January 2011 and...
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