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Radiotherapy and immune checkpoint blockades: a snapshot in 2016

Koo T, Kim IA

Immune checkpoint blockades including monoclonal antibodies (mAbs) of cytotoxic T-lymphocyte antigen-4 (CTLA-4), programmed death-1 (PD-1), and programmed death-ligand 1 (PD-L1) have been emerged as a promising anticancer therapy. Several immune...
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The impact of radiotherapy on clinical outcomes in parameningeal rhabdomyosarcoma

Choi Y, Lim DH

PURPOSE: Radiotherapy (RT) is considered a mainstay of treatment in parameningeal rhabdomyosarcoma (PM-RMS). We aim to determine the treatment outcomes and prognostic factors for PM-RMS patients who treated with RT....
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Hypofractionated stereotactic body radiotherapy in low- and intermediate-risk prostate carcinoma

Kim HJ, Phak JH, Kim WC

PURPOSE: Stereotactic body radiotherapy (SBRT) takes advantage of low α/β ratio of prostate cancer to deliver a large dose in few fractions. We examined clinical outcomes of SBRT using CyberKnife...
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Postoperative radiotherapy appeared to improve the disease free survival rate of patients with extrahepatic bile duct cancer at high risk of loco-regional recurrence

Kim MY, Kim JH, Kim Y, Byun SJ

PURPOSE: To investigate the outcomes of postoperative radiotherapy (RT), in patients with extrahepatic bile duct (EHBD) cancer by comparing the survival rate between patients undergoing surgery alone or surgery plus...
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Nodal tumor response according to the count of peripheral blood lymphocyte subpopulations during preoperative chemoradiotherapy in locally advanced rectal cancer

Heo J, Oh YT, Noh OK, Chun M, Park JE, Cho SR

PURPOSE: The objective of this prospective study was to evaluate the relationship between the circulating lymphocyte subpopulation counts during preoperative chemoradiotherapy (CRT) and tumor response in locally advanced rectal cancer. MATERIALS...
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Tumor hypoxia and reoxygenation: the yin and yang for radiotherapy

Hong BJ, Kim J, Jeong H, Bok S, Kim YE, Ahn GO

Tumor hypoxia, a common feature occurring in nearly all human solid tumors is a major contributing factor for failures of anticancer therapies. Because ionizing radiation depends heavily on the presence...
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Early hypopharyngeal cancer treated with different therapeutic approaches: a single-institution cohort analysis

Kim N, Lee J, Kim KH, Park JW, Lee CG, Keum KC

PURPOSE: Early hypopharyngeal squamous cell carcinoma (HPSCC) is a rarely diagnosed disease, for which the optimal treatment has not been defined yet. We assessed patterns of failure and outcomes in...
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Analysis of treatment outcomes for primary tonsillar lymphoma

Lee YH, Cho SG, Jung SE, Kim SH, O JH, Park GS, Yang SW, Lee IS, Rhee CK, Choi BO

PURPOSE: Although each Waldeyer’s ring sub-site is considered an independent prognostic factor, few studies have assessed the prognosis and treatment of tonsillar lymphoma. Treatment outcomes were analyzed in patients with...
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Dosimetric comparison of intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) in total scalp irradiation: a single institutional experience

Ostheimer , Hübsch P, Janich M, Gerlach R, Vordermark D

PURPOSE: Total scalp irradiation (TSI) is a rare but challenging indication. We previously reported that non-coplanar intensity-modulated radiotherapy (IMRT) was superior to coplanar IMRT in organ-at-risk (OAR) protection and target...
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Treatment outcomes after adjuvant radiotherapy following surgery for patients with stage I endometrial cancer

Kim J, Lee KJ, Park KR, Ha B, Kim YJ, Jung W, Lee R, Kim SC, Moon HS, Ju W, Kim YH, Lee J

PURPOSE: The purpose of this study is to evaluate the treatment outcomes of adjuvant radiotherapy using vaginal brachytherapy (VB) with a lower dose per fraction and/or external beam radiotherapy (EBRT)...
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