- Rapid detection of deformed wing virus in honeybee using ultra-rapid qPCR and a DNA-chip
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Kim JM, Lim SJ, Kim S, Kim M, Kim B, Tai TA, Kim S, Yoon B
- KMID: 2469019
- J Vet Sci.
- 2020 Jan;21(1):e4.
- doi: 10.4142/jvs.2020.21.e4
Fast and accurate detection of viral RNA pathogens is important in apiculture. A polymerase chain reaction (PCR)-based detection method has been developed, which is simple, specific, and sensitive. In this... -
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- Antiviral Activity of Gemcitabine Against Echovirus 30 Infection in Vitro
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Choi HJ, Song JH, Yoon K
- KMID: 2468026
- J Bacteriol Virol.
- 2019 Dec;49(4):203-211.
- doi: 10.4167/jbv.2019.49.4.203
Echovirus 30 is one of the major causes of meningitis in children and adults. The purpose of our current study was to investigate whether selected antiviral drugs could provide antiviral... -
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- Rapid Whole-genome Sequencing of Zika Viruses using Direct RNA Sequencing
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Kim JH, Kim J, Koo BS, Oh H, Hong JJ, Hwang ES
- KMID: 2468031
- J Bacteriol Virol.
- 2019 Sep;49(3):115-123.
- doi: 10.4167/jbv.2019.49.3.115
Zika virus (ZIKV) is one of the pathogens which is transmitted world widely, but there are no effective drugs and vaccines. Whole genome sequencing (WGS) of viruses could be applied... -
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- Cysteine-Added Mutants of Turnip Yellow Mosaic Virus
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Shin IS, Kim D, Cho TJ
- KMID: 2452066
- J Bacteriol Virol.
- 2018 Dec;48(4):137-146.
- doi: 10.4167/jbv.2018.48.4.137
Native turnip yellow mosaic virus (TYMV) is relatively unreactive to maleimide agents, indicating few reactive thiol groups on TYMV. In the present study, we aimed to construct TYMV mutants that... -
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- The Role of Serum HBV-RNA Levels as a Marker of Intrahepatic Viral and Histologic Activity
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Kwon JH
- KMID: 2415490
- Korean J Gastroenterol.
- 2018 May;71(5):297-299.
- doi: 10.4166/kjg.2018.71.5.297
No abstract available. -
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- Transaminase Changes in Korean Rheumatoid Arthritis Patients with Chronic Hepatitis C after Biologic Therapy
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Kwon HM, Shin K, Moon JY, Lee SS, Chung WT, Lee J, Lee SH, Kang SW, Suh CH, Hong SJ, Song R, Choe JY, Song YW
- KMID: 2408928
- J Rheum Dis.
- 2018 Apr;25(2):108-115.
- doi: 10.4078/jrd.2018.25.2.108
OBJECTIVE: Coexisting chronic hepatitis C can be problematic when treating rheumatoid arthritis (RA). This study examined the changes in the transaminase and viral load in hepatitis C virus (HCV)-infected RA... -
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- Prevalence of Respiratory Viral Infections in Korean Adult Asthmatics With Acute Exacerbations: Comparison With Those With Stable State
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Seo KH, Bae DJ, Kim JN, Lee HS, Kim YH, Park JS, Kim MS, Chang HS, Son JH, Baek DG, Lee JS, Park CS
- KMID: 2421659
- Allergy Asthma Immunol Res.
- 2017 Nov;9(6):491-498.
- doi: 10.4168/aair.2017.9.6.491
PURPOSE: Viral infections are involved in ~50% of exacerbations among Caucasian adult asthmatics. However, there have been few reports on the causative virus of exacerbations in Korean adult asthmatics. Thus,... -
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- Antiviral Activity of Itraconazole against Echovirus 30 Infection In Vitro
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Lee JS, Choi HJ, Song JH, Ko HJ, Yoon K, Seong JM
- KMID: 2395841
- Osong Public Health Res Perspect.
- 2017 Oct;8(5):318-324.
- doi: 10.24171/j.phrp.2017.8.5.05
OBJECTIVES: Echovirus 30 is a major cause of meningitis in children and adults. The aim of this study was to investigate whether the antifungal drug itraconazole could exhibit antiviral activity... -
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- Meta-analysis of the Efficacy and Safety of Grazoprevir and Elbasvir for the Treatment of Hepatitis C Virus Infection
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Kang MG, Kang MJ, Ji E, Yoo BK
- KMID: 2405669
- Korean J Clin Pharm.
- 2017 Sep;27(3):150-160.
- doi: 10.24304/kjcp.2017.27.3.150
OBJECTIVE: Recently, a fixed combination of grazoprevir and elbasvir (GE) has been introduced to the arsenal of chemotherapeutics to fight against this virus. The study aimed to provide information on... -
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- Effect of the fourth nucleotide at the 3′ end of neuraminidase and matrix viral genomic RNA on the pathogenicity of influenza virus A/PR/8/34
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Lee CY, Kwon HJ, Nguyen TT, Kim I, Jang HK, Kim JH
- KMID: 2412555
- J Vet Sci.
- 2017 Aug;18(S1):307-313.
- doi: 10.4142/jvs.2017.18.S1.307
Twelve nucleotides located at the 3′ end of viral genomic RNA (vRNA) are conserved among influenza A viruses (IAV) and have a promoter function. Hoffmann's 8-plasmid reverse genetics vector system... -
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- In vitro antiviral activity of ribavirin against severe fever with thrombocytopenia syndrome virus
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Lee MJ, Kim KH, Yi J, Choi SJ, Choe PG, Park WB, Kim NJ, Oh MD
- KMID: 2387719
- Korean J Intern Med.
- 2017 Jul;32(4):731-737.
- doi: 10.3904/kjim.2016.109
BACKGROUND/AIMS: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by severe fever with thrombocytopenia syndrome virus (SFTSV), a novel bunyavirus. As yet, there is no effective... -
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- Barriers to treatment of failed or interferon ineligible patients in the era of DAA: single center study
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Seo KI, Yun BC, Li WJ, Lee SU, Han BH, Park ET
- KMID: 2412117
- Clin Mol Hepatol.
- 2017 Mar;23(1):74-79.
- doi: 10.3350/cmh.2016.0052
BACKGROUND/AIMS: Interferon-based treatment is not appropriate for a large number of patients with chronic hepatitis C for various medical and social reasons. Newly developed directly acting antivirals (DAAs) have been... -
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- Efficacy and safety of daclatasvir plus asunaprevir for Korean patients with HCV genotype Ib infection: a retrospective multi-institutional study
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Cho BW, Kim SB, Song IH, Lee SH, Kim HS, Lee TH, Kang YW, Kim SH, Lee BS, Chae HB
- KMID: 2412114
- Clin Mol Hepatol.
- 2017 Mar;23(1):51-56.
- doi: 10.3350/cmh.2016.0053
BACKGROUND/AIMS: The combination of daclatasvir (DCV) and asunaprevir (ASV) has demonstrated a high sustained virologic response at 12 weeks (SVR12) and a low rate of adverse events in previous clinical... -
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- Database construction of small–molecule inhibitors as bovine viral diarrhea virus (BVDV) RNA-dependent RNA polymerase: a cheminformatics approach
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Chai HH, Choi BH, Park JE, Kim UH, Cho YM, Lim D
- KMID: 2377351
- J Biomed Transl Res.
- 2017 Mar;18(1):13-23.
- doi: 10.12729/jbr.2017.18.1.013
Bovine viral diarrhea virus (BVDV) is a major pathogen that may be one of the main reasons for economic losses in the livestock industry. BVDV is a well-characterized member of... -
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- Establishment of reverse transcription polymerase chain reaction for detection of Getah virus infection in livestock
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Lee SH, Yang DK, Kim HH, Choi SS, Cho IS
- KMID: 2376877
- Korean J Vet Res.
- 2017 Mar;57(1):37-42.
- doi: 10.14405/kjvr.2017.57.1.37
Getah virus (GETV) infection causes sporadic outbreaks of mild febrile illness in horses and reproductive failure in pigs. In this study, we established a reverse transcription polymerase chain reaction (RT-PCR)... -
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- Dengue Virus Serotypes Circulating in Khyber Pakhtunkhwa Province, Pakistan, 2013-2015
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Suleman M, Faryal R, Alam MM, Sharif S, Shaukat S, Aamir UB, Khurshid A, Angez M, Umair M, Sufian MM, Arshad Y, Zaidi SS
- KMID: 2373633
- Ann Lab Med.
- 2017 Mar;37(2):151-154.
- doi: 10.3343/alm.2017.37.2.151
From 2013 to 2015, the National Institute of Health, Pakistan, received 1,270 blood samples of suspected dengue cases reported from inpatient and outpatient departments of various hospitals in Khyber Pakhtunkhwa... -
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- Importance of Specimen Type and Quality in Diagnosing Middle East Respiratory Syndrome
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Huh HJ, Ko JH, Kim YE, Park CH, Hong G, Choi R, Yu S, Cho SY, Kang JM, Lee MK, Ki CS, Kang ES, Lee NY, Kim JW, Kim YJ, Ha YE, Kang CI, Chung DR, Peck KR, Song JH
- KMID: 2373621
- Ann Lab Med.
- 2017 Jan;37(1):81-83.
- doi: 10.3343/alm.2017.37.1.81
No abstract available. -
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- Clinical Utility of a New Automated Hepatitis C Virus Core Antigen Assay for Prediction of Treatment Response in Patients with Chronic Hepatitis C
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Kim MN, Kim HS, Kim JK, Kim BK, Kim SU, Park JY, Kim DY, Ahn SH, Han KH
- KMID: 2468276
- J Korean Med Sci.
- 2016 Sep;31(9):1431-1437.
- doi: 10.3346/jkms.2016.31.9.1431
Hepatitis C virus core antigen (HCV Ag) is a recently developed marker of hepatitis C virus (HCV) infection. We investigated the clinical utility of the new HCV Ag assay for... -
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- Comparative Evaluation of Three Homogenization Methods for Isolating Middle East Respiratory Syndrome Coronavirus Nucleic Acids From Sputum Samples for Real-Time Reverse Transcription PCR
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Sung H, Yong D, Ki CS, Kim JS, Seong MW, Lee H, Kim MN
- KMID: 2373576
- Ann Lab Med.
- 2016 Sep;36(5):457-462.
- doi: 10.3343/alm.2016.36.5.457
BACKGROUND: Real-time reverse transcription PCR (rRT-PCR) of sputum samples is commonly used to diagnose Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Owing to the difficulty of extracting RNA from sputum... -
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- Analytical and Clinical Validation of Six Commercial Middle East Respiratory Syndrome Coronavirus RNA Detection Kits Based on Real-Time Reverse-Transcription PCR
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Kim MN, Ko YJ, Seong MW, Kim JS, Shin BM, Sung H
- KMID: 2373575
- Ann Lab Med.
- 2016 Sep;36(5):450-456.
- doi: 10.3343/alm.2016.36.5.450
BACKGROUND: During the 2015 outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV), six different commercial MERS-CoV RNA detection kits based on real-time reverse-transcription polymerase chain reaction (rRT-PCR) were available in... -
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