- Upregulated Long Noncoding RNA LINC01234 Predicts Unfavorable Prognosis for Colorectal Cancer and Negatively Correlates With KLF6 Expression
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Jiang X, Zhu Q, Wu P, Zhou F, Chen J
- KMID: 2460913
- Ann Lab Med.
- 2020 Mar;40(2):155-163.
- doi: 10.3343/alm.2020.40.2.155
BACKGROUND: LINC01234, a long noncoding RNA (lncRNA), is overexpressed in several cancers, including colorectal cancer (CRC). We investigated the role of LINC01234 in CRC development and confirmed its correlation with... -
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- c-Myc-Induced Long Non-Coding RNA Small Nucleolar RNA Host Gene 7 Regulates Glycolysis in Breast Cancer
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Zhang L, Fu Y, Guo H
- KMID: 2470891
- J Breast Cancer.
- 2019 Dec;22(4):533-547.
- doi: 10.4048/jbc.2019.22.e54
PURPOSE: Recent studies have shown that long non-coding RNA (lncRNA) play an important role in cancer metabolism and development. The lncRNA small nucleolar RNA host gene 7 (SNHG7) was reported... -
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- Long non-coding RNA linc00152 acting as a promising oncogene in cancer progression
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Seo D, Kim D, Kim W
- KMID: 2468862
- Genomics Inform.
- 2019 Dec;17(4):e36.
- doi: 10.5808/GI.2019.17.4.e36
The incidence and mortality rate of cancer continues to gradually increase, although considerable research effort has been directed at elucidating the molecular mechanisms underlying biomarkers responsible for tumorigenesis. Accumulated evidence... -
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- Long non-coding RNA T-cell leukemia/lymphoma 6 serves as a sponge for miR-21 modulating the cell proliferation of retinoblastoma through PTEN
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Tao S, Wang W, Liu P, Wang H, Chen W
- KMID: 2461037
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):449-458.
- doi: 10.4196/kjpp.2019.23.6.449
Retinoblastoma (Rb) is one of the most common eye malignancies occur in childhood. The crucial roles of non-coding RNAs, particularly long non-coding RNAs (lncRNAs) and microRNAs (miRNAs), have been widely... -
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- LncRNA MALAT1/MiR-145 Adjusts IL-1β-Induced Chondrocytes Viability and Cartilage Matrix Degradation by Regulating ADAMTS5 in Human Osteoarthritis
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Liu C, Ren S, Zhao S, Wang Y
- KMID: 2460226
- Yonsei Med J.
- 2019 Nov;60(11):1081-1092.
- doi: 10.3349/ymj.2019.60.11.1081
PURPOSE: Accumulating evidence suggests that microRNA-145 (miR-145) plays an important role in osteoarthritis (OA), which is a chronic progressive joint disease. Long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1)... -
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- The Long Non-Coding RNA CASC2 Suppresses Cell Viability, Migration, and Invasion in Hepatocellular Carcinoma Cells by Directly Downregulating miR-183
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Sun J, Liu L, Zou H, Yu W
- KMID: 2459143
- Yonsei Med J.
- 2019 Oct;60(10):905-913.
- doi: 10.3349/ymj.2019.60.10.905
PURPOSE: Hepatocellular carcinoma (HCC) is the most common malignant tumor of liver cells. Researchers have reported that cancer susceptibility candidate 2 (CASC2), a long non-coding RNA, is down-regulated in various... -
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- Long Intergenic Non-Protein Coding RNA 665 Regulates Viability, Apoptosis, and Autophagy via the MiR-186-5p/MAP4K3 Axis in Hepatocellular Carcinoma
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Shan Y, Li P
- KMID: 2457480
- Yonsei Med J.
- 2019 Sep;60(9):842-853.
- doi: 10.3349/ymj.2019.60.9.842
PURPOSE: Long intergenic non-protein coding RNA 665 (LINC00665) plays a vital role in the development of cancer. Its function in hepatocellular carcinoma (HCC), however, remains largely unknown. MATERIALS AND METHODS: The... -
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- Long Noncoding RNA MALAT1 Regulates Hepatocellular Carcinoma Growth Under Hypoxia via Sponging MicroRNA-200a
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Zhao ZB, Chen F, Bai XF
- KMID: 2452953
- Yonsei Med J.
- 2019 Aug;60(8):727-734.
- doi: 10.3349/ymj.2019.60.8.727
PURPOSE: Hepatocellular carcinoma (HCC) is a common cancer worldwide. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long noncoding RNA (lncRNA), has been reported to be aberrantly expressed in hypoxic cancer... -
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- Long Non-Coding RNA LINC00525 Promotes the Stemness and Chemoresistance of Colorectal Cancer by Targeting miR-507/ELK3 Axis
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Wang S, Li J, Yang X
- KMID: 2465904
- Int J Stem Cells.
- 2019 Jul;12(2):347-359.
- doi: 10.15283/ijsc19041
BACKGROUND AND OBJECTIVES: This study aims to explore the effects of a long non-coding RNA, LINC00525, on colorectal cancer (CRC) and its underlying molecular mechanisms. METHODS: The qPCR, MTT, colony formation,... -
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- Long Noncoding RNA N-BLR Upregulates the Migration and Invasion of Gastric Adenocarcinoma
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Youn YH, Byun HJ, Yoon JH, Park CH, Lee SK
- KMID: 2458526
- Gut Liver.
- 2019 Jul;13(4):421-429.
- doi: 10.5009/gnl18408
BACKGROUND/AIMS: Gastric cancer is one of the most common malignant tumors worldwide with poor prognosis due to a lack of effective treatment modalities. Recent research showed that a long noncoding... -
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- Long Noncoding RNA NEAT1 Aggravates Aβ-Induced Neuronal Damage by Targeting miR-107 in Alzheimer's Disease
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Ke S, Yang Z, Yang F, Wang X, Tan J, Liao B
- KMID: 2450404
- Yonsei Med J.
- 2019 Jul;60(7):640-650.
- doi: 10.3349/ymj.2019.60.7.640
PURPOSE: Alzheimer's disease (AD) is the most common neurodegenerative disease, with a rising prevalence worldwide. Long noncoding RNAs (lncRNAs) have been found to play important roles in the development and... -
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- Knockdown of LncRNA H19 Relieves LPS-Induced Damage by Modulating miR-130a in Osteoarthritis
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Hu Y, Li S, Zou Y
- KMID: 2450194
- Yonsei Med J.
- 2019 Apr;60(4):381-388.
- doi: 10.3349/ymj.2019.60.4.381
PURPOSE: Osteoarthritis (OA) is a commonly occurring illness without a definitive cure, at present. Long non-coding RNAs (lncRNAs) have been widely confirmed to be involved in the modulation of OA... -
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- The Long Noncoding RNA NEAT1 Targets miR-34a-5p and Drives Nasopharyngeal Carcinoma Progression via Wnt/β-Catenin Signaling
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Ji Y, Wang M, Li X, Cui F
- KMID: 2450188
- Yonsei Med J.
- 2019 Apr;60(4):336-345.
- doi: 10.3349/ymj.2019.60.4.336
PURPOSE: Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) has been deemed an oncogene in many human cancers. However, the underlying mechanism of NEAT1 in nasopharyngeal carcinoma (NPC) progression... -
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- Regulation Mechanism of Long Noncoding RNAs in Colon Cancer Development and Progression
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Tang X, Qiao X, Chen C, Liu Y, Zhu J, Liu J
- KMID: 2450186
- Yonsei Med J.
- 2019 Apr;60(4):319-325.
- doi: 10.3349/ymj.2019.60.4.319
Colorectal cancer (CRC) is the second most common cause of cancer-related death worldwide, and its high rates of relapse and metastasis are associated with a poor prognosis. Despite extensive research,... -
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- Potential Implications of Long Noncoding RNAs in Autoimmune Diseases
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Hur K, Kim SH, Kim JM
- KMID: 2438912
- Immune Netw.
- 2019 Feb;19(1):e4.
- doi: 10.4110/in.2019.19.e4
Long noncoding RNAs (lncRNAs) are non-protein coding RNAs of more than 200 nucleotides in length. Despite the term “noncodingâ€, lncRNAs have been reported to be involved in gene expression. Accumulating... -
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- Circulating HOTAIR LncRNA Is Potentially Up-regulated in Coronary Artery Disease
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Avazpour N, Hajjari M, Yazdankhah S, Sahni A, Foroughmand AM
- KMID: 2439215
- Genomics Inform.
- 2018 Dec;16(4):e25.
- doi: 10.5808/GI.2018.16.4.e25
Coronary artery disease (CAD) is one of the leading causes of death and disability all around the world. Recent studies have revealed that aberrantly regulated long non-coding RNA (lncRNA) as... -
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- Roles of Oncogenic Long Non-coding RNAs in Cancer Development
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Do H, Kim W
- KMID: 2439208
- Genomics Inform.
- 2018 Dec;16(4):e18.
- doi: 10.5808/GI.2018.16.4.e18
Long non-coding RNAs (lncRNAs) are classified as RNAs that are longer than 200 nucleotides and cannot be translated into protein. Several studies have demonstrated that lncRNAs are directly or indirectly... -
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- Altered expression of MALAT1 lncRNA in chronic lymphocytic leukemia patients, correlation with cytogenetic findings
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Ahmadi A, Kaviani S, Yaghmaie M, Pashaiefar H, Ahmadvand , Jalili M, Alimoghaddam K, Eslamijouybari M, Ghavamzadeh A
- KMID: 2429307
- Blood Res.
- 2018 Dec;53(4):320-324.
- doi: 10.5045/br.2018.53.4.320
BACKGROUND: Recent studies have devoted much attention to non-protein-coding transcripts in relation to a wide range of malignancies. MALAT1, a long non-coding RNA, has been reported to be associated with... -
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- Upregulation of long non-coding RNA XIST has anticancer effects on epithelial ovarian cancer cells through inverse downregulation of hsa-miR-214-3p
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Wang C, Qi S, Xie C, Li C, Wang P, Liu D
- KMID: 2431244
- J Gynecol Oncol.
- 2018 Nov;29(6):e99.
- doi: 10.3802/jgo.2018.29.e99
OBJECTIVE: The present study is to evaluate the biological functions of long non-coding RNA (lncRNA), X-inactive specific transcript, X-inactive specific transcript (XIST) in human epithelial ovarian cancer (EOC). METHODS: XIST was... -
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- LncRNA XLOC_006390 facilitates cervical cancer tumorigenesis and metastasis as a ceRNA against miR-331-3p and miR-338-3p
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Luan X, Wang Y
- KMID: 2431240
- J Gynecol Oncol.
- 2018 Nov;29(6):e95.
- doi: 10.3802/jgo.2018.29.e95
OBJECTIVE: Cervical cancer is one of the most common malignant tumors. Our previous results showed that long non-coding RNA (lncRNA) XLOC_006390 plays an important role in cervical cancer. In this... -
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