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Phenotype of Asthma-COPD Overlap in COPD and Severe Asthma Cohorts

Joo H, Park SY, Park SY, Park SY, Kim SH, Cho YS, Yoo KH, Jung KS, Rhee CK

Background: Asthma and chronic obstructive pulmonary disease (COPD) are airway diseases with similar clinical manifestations, despite differences in pathophysiology. AsthmaCOPD overlap (ACO) is a condition characterized by overlapping clinical features...
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Role of Nuclear Factor Erythroid 2-Related Factor 2 in Chronic Obstructive Pulmonary Disease

Ban WH, Rhee CK

Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation due to chronic airway inflammation and destruction of the alveolar structure from persistent exposure to oxidative stress. The body has...
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Usefulness of Pulmonary Rehabilitation in Non-Small Cell Lung Cancer Patients Based on Pulmonary Function Tests and Muscle Analysis Using Computed Tomography Images

Choi J, Yang Z, Lee J, Lee JH, Kim HK, Yong HS, Lee SY

Purpose The usefulness of rehabilitation in patients with reduced lung function before lung surgery remains unclear, and there is no adequate method for evaluating the effect of rehabilitation. We aimed...
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Optimal Cut-Off Points of 4-meter Gait Speed to Discriminate Functional Exercise Capacity and Health Status in Older patients with Chronic Obstructive Pulmonary Disease

Ozsoy I, Kodak MI, Zerman N, Kararti C, Erturk A

Background: Gait speed, a vital sign of health and functional capacity, is commonly used to measure mobility. Although studies have assessed gait speed in older adults and individuals with chronic...
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Acute exacerbation of COPD increases the risk of hip fractures: a nested case-control study from the Korea National Health Insurance Service

Gu KM, Yoon SW, Jung SY, Baek MS, Kim WY, Jung JW, Choi JC, Shin JW, Kim JY, Choi BW, Park IW

Background/Aims: Hip fracture and acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) could increase mortality in patients with COPD. There are no data on the relationship between AE-COPD and hip...
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The Effectiveness and Harms of Screening for Chronic Obstructive Pulmonary Disease: An Updated Systematic Review and Meta-Analysis

Choi N, Jang S, Yoo KH, Rhee CK, Kim Y

Background: This study aimed to perform meta-analyses to update a previous systematic review (SR) conducted by the US Preventive Services Task Force (USPSTF) to evaluate the benefits and harms of...
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Effects of Farinelli Breating Exercise on Respiratory Function and Symptoms in Patients with Chronic Obstructive Pulmonary Disease

Ittinirundorn S, Wongsaita N, Somboonviboon D, Tongtako W

Background: Farinelli breathing (FB) exercise is a typical breathing exercise used by singers. This study aimed to compare effects of FB exercise and diaphragmatic breathing (DB) exercise on respiratory function...
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Status of Studies Investigating Asthma–Chronic Obstructive Pulmonary Disease Overlap in Korea: A Review

Jo YS

There is a considerable number of individuals who exhibit features of both asthma and chronic obstructive pulmonary disease (COPD), defined as asthma-COPD overlap (ACO). Many studies have reported that these...
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Metformin alleviates chronic obstructive pulmonary disease and cigarette smoke extract-induced glucocorticoid resistance by activating the nuclear factor E2-related factor 2/heme oxygenase-1 signaling pathway

Tao F, Zhou Y, Wang M, Wang C, Zhu W, Han Z, Sun N, Wang D

Chronic obstructive pulmonary disease (COPD) is an important healthcare problem worldwide. Often, glucocorticoid (GC) resistance develops during COPD treatment. As a classic hypoglycemic drug, metformin (MET) can be used as...
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Prevalence and impact of airway diseases on clinical outcomes in idiopathic pulmonary fibrosis

Park H, Cho J, Lee J, Park YS, Lee CH, Lee SM, Yoo CG, Kim YW, Han SK, Choi SM

Background/Aims: The prevalence and effects of airway diseases, including asthma, eosinophilic bronchitis (EB), chronic obstructive pulmonary disease (COPD), and asthma-COPD overlap (ACO) have not been thoroughly studied in patients with...
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Expeditious Resolution of Giant Bullae with Endobronchial Valves and Percutaneous Catheter Insertion

Im Y, Jeong BH, Park HY, Kim TS, Kim H

As bullae contribute to decreased lung function in chronic obstructive pulmonary disease (COPD) patients, effective decompression of large bullae is important. Bronchoscopic lung volume reduction via endobronchial one-way valves is...
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Successful noninvasive ventilation in a severely acidotic and hypercapnic comatose COVID-19 patient with multiple comorbidities: a case report

Poonuraparampil JA, Karim HMR, Kesavankutty MP, Nayak PP

Effective use of noninvasive ventilation in patients with chronic obstructive pulmonary disease is well-known. However, noninvasive ventilation in patients presenting with altered sensorium and severe acidosis (pH
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Digital Healthcare for Airway Diseases from Personal Environmental Exposure

Park Y, Lee C, Jung JY

Digital technologies have emerged in various dimensions of human life, ranging from education to professional services to wellbeing. In particular, health products and services have expanded by the use and...
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Chronic Obstructive Pulmonary Disease Is Not Associated with a Poor Prognosis in COVID-19

Kim Y, An TJ, Park YB, Kim K, Cho DY, Rhee CK, Yoo KH

Background: The effect of underlying chronic obstructive pulmonary disease (COPD) on coronavirus disease 2019 (COVID-19) during a pandemic is controversial. The purpose of this study was to examine the prognosis...
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The Long-term Efficacy of Domiciliary Noninvasive Positive-Pressure Ventilation in Chronic Obstructive Pulmonary Disease: A Meta-Analysis of Randomized Controlled Trials

Park SY, Yoo KH, Park YB, Rhee CK, Park J, Park HY, Hwang YI, Park DA, Sim YS

Background: We evaluated the long-term effects of domiciliary noninvasive positive-pressure ventilation (NIPPV) used to treat patients with chronic obstructive pulmonary disease (COPD). Methods: Databases were searched to identify randomized controlled trials...
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A Multicenter Study to Identify the Respiratory Pathogens Associated with Exacerbation of Chronic Obstructive Pulmonary Disease in Korea

Lee HW, Sim YS, Jung JY, Seo H, Park JW, Min KH, Lee JH, Kim BK, Lee MG, Oh YM, Ra SW, Kim TH, Hwang Yi, Rhee CK, Joo H, Lee EG, Lee JH, Park HY, Kim WJ, Um SJ, Choi JY, Lee CH, An TJ, Park Y, Yoon YS, Park JH, Yoo KH, Kim DK

Background: Although respiratory tract infection is one of the most important factors triggering acute exacerbation of chronic obstructive pulmonary disease (AE-COPD), limited data are available to suggest an epidemiologic pattern...
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Korean physician prescription patterns for home oxygen therapy in chronic obstructive pulmonary disease patients

Kim Y, Kim HI, Park JY, Hong JY, Kim JH, Min KH, Rhee CK, Park S, Lee CY, Lim SY, Jang SH, Hwang YI

Background/Aims: Hypoxemia in chronic obstructive pulmonary disease (COPD) leads to reduced ability to exercise, decreased quality of life, and, eventually, increased mortality. Home oxygen therapy in patients with severe COPD...
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Analysis on the ratio of emergency department visits by elderly and non-elderly patients based on disease and particulate matter concentration in South Korea: a multicenter cross-sectional observational study

Han GH, Park S, Lee Y, Jang HY, Cho YS, Chung H, Kim SI, Seo BS, Sohn YW, Park J

  • KMID: 2524968
  • J Korean Soc Emerg Med.
  • 2021 Dec;32(6):698-711.
Objective: Many previous studies have reported relationships between particulate matter < 10 μm (PM10) and asthma in emergency department (ED) settings, but few have examined its effect on cerebrovascular diseases....
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Regional Anesthesia for Abdominal Surgery in a Patient with Severe Chronic Respiratory Failure: A Case Report

Lee M, Woo Y, Jung J, Chung YH, Koo BS, Cho SH

General anesthesia is associated with a risk for postoperative pulmonary complications. The risk is even higher in patients with chronic respiratory failure, and postoperative mortality rates are high. Proper perioperative...
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Eosinophilic endotype of chronic obstructive pulmonary disease: similarities and differences from asthma

Li A, Chan HP, Gan PX, Liew MF, Wong WF, Lim HF

Approximately 25% to 40% of patients with chronic obstructive pulmonary disease (COPD) have the eosinophilic endotype. It is important to identify this group accurately because they are more symptomatic and...
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