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The Effectiveness of Methylphenidate in the Treatment of Encopresis Independent from Attention-Deficit Hyperactivity Disorder Symptoms

Akca OF, Yilmaz S

Several medications are reported to be effective in treatment of encopresis. However, mechanisms of action related to these drugs are not known. We report a patient with ADHD and encopresis...
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Pain and Depression: A Neurobiological Perspective of Their Relationship

Han C, Pae CU

Remarkable progresses have been achieved regarding the understanding of the neurobiological bases of pain and depression. The principal role of neurotransmitters, neuromodulators, and neurohormones has been proposed in the development...
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New-Onset Mania Following Bariatric Surgery

Nepal H, Bhattarai , Agustin ET

Obesity has become a major public health problem over the past two decades. Non-surgical management of obesity does not often achieve its long term goals. Surgical treatment is roaring in...
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The Short-Term Effects of Risperidone-Induced Hyperprolactinemia on Lipid Metabolism in Drug-Naive Children and Adolescents

Park EJ, Park YM

OBJECTIVE: The present cross-sectional study was designed to assess the risk of elevated prolactin levels and other hormonal or metabolic changes in children and adolescents taking risperidone. METHODS: Twenty-five children and...
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Association of Hair Manganese Level with Symptoms in Attention-Deficit/Hyperactivity Disorder

Shin DW, Kim EJ, Lim SW, Shin YC, Oh KS, Kim EJ

OBJECTIVE: The study examined the association between hair manganese level and symptoms of attention-deficit/hyperactivity disorder (ADHD) in Korean children. METHODS: Forty clinic-referred children with ADHD and 43 normal control children participated...
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Stigma of Mental Illnesses as Perceived by North Korean Defectors Living in South Korea

Ahn JH, Kim WH, Choi HJ, Jeon JY, Song IG, Bae JN

OBJECTIVE: This study aims to provide the information of the stigmas of mental illness such as psychosis, alcoholism, attempt suicide, and depression among North Korean defectors. METHODS: We examined stigma for...
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Clinical Characteristics and Precipitating Factors of Adolescent Suicide Attempters Admitted for Psychiatric Inpatient Care in South Korea

Park S, Kim JW, Kim BN, Bae JH, Shin MS, Yoo HJ, Cho SC

OBJECTIVE: We aimed to examine the rates, correlates, methods, and precipitating factors of suicide attempts among adolescent patients admitted for psychiatric inpatient care from 1999 to 2010 in a university...
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Possible Association between Serotonin Transporter Gene Polymorphism and Suicide Behavior in Major Depressive Disorder

Lee HY, Hong JP, Hwang JA, Lee HJ, Yoon HK, Lee BH, Kim YK

OBJECTIVE: The serotonin transporter (5-HTT) genes are major candidate genes for modulating the suicidal behavior. We investigated the association between serotonin transporter polymorphisms and suicidal behavior in patients with major...
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A Long Term Effects of a New Onset Psychosis after DBS Treated with Quetiapine in a Patient with Parkinson's Disease

Piccoli S, Perini G, Pizzighello S, Vestri A, Ferri G, Toffanin T, Follador H, Martinuzzi A

Deep Brain Stimulation represents a therapeutic option for PD patients. In this paper, we present and discuss a case of acute delirium and psychosis manifesting after DBS in a 58-years-old...
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Cut-Off Scores of the Children's Depression Inventory for Screening and Rating Severity in Korean Adolescents

Bang YR, Park JH, Kim SH

OBJECTIVE: The aim was to establish an optimal cut-off score of the Children's Depression Inventory (CDI) for detecting depression and rating severity in Korean adolescents. METHODS: A total of 468 students...
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Evidence for Association between the Brain-Derived Neurotrophic Factor Gene and Panic Disorder: A Novel Haplotype Analysis

Han EJ, Kim YK, Hwang JA, Kim SH, Lee HJ, Yoon HK, Na KS

OBJECTIVE: Panic disorder (PD) is a common psychiatric disorder with a complex etiology, and several studies have suggested that it has a genetic component. Brain-derived neurotrophic factor (BDNF) is the...
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Bupropion for Interferon-Alpha-Induced Depression in Patients with Hepatitis C Viral Infection: An Open-Label Study

Chen WC, Lai HC, Su WP, Palani M, Su KP

Interferon (IFN)-alpha therapy for chronic hepatitis C virus (HCV) infection is frequently associated with major depressive episodes. Bupropion, a commonly used antidepressant agent, has recently found to have strong anti-inflammatory...
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Simultaneous Comparison of Efficacy and Tolerability of Second-Generation Antipsychotics in Schizophrenia: Mixed-Treatment Comparison Analysis Based on Head-to-Head Trial Data

Oh GH, Yu JC, Choi KS, Joo EJ, Jeong SH

OBJECTIVE: Second-generation antipsychotics have been repeatedly shown to be superior to placebo. However, the comparative efficacy among these drugs has not been systematically evaluated. In this study, we used Mixed...
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Neural Network Based Response Prediction of rTMS in Major Depressive Disorder Using QEEG Cordance

Erguzel TT, Ozekes S, Gultekin S, Tarhan N, Hizli Sayar G, Bayram A

OBJECTIVE: The combination of repetitive transcranial magnetic stimulation (rTMS), a non-pharmacological form of therapy for treating major depressive disorder (MDD), and electroencephalogram (EEG) is a valuable tool for investigating the...
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The Relationship between Type D Personality and Suicidality in Low-Income, Middle-Aged Adults

Yoon DH, Kim SJ, Lee JH, Kim PM, Park DH, Ryu SH, Yu J, Ha JH

OBJECTIVE: Low-income adults are considered to be a group at high risk for suicide. We sought to examine the effect of type D personality and other socio-demographic factors on suicidality...
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Abnormal Activation of the Social Brain Network in Children with Autism Spectrum Disorder: An fMRI Study

Kim SY, Choi US, Park SY, Oh SH, Yoon HW, Koh YJ, Im WY, Park JI, Song DH, Cheon KA, Lee CU

OBJECTIVE: The aim of this study is to investigate abnormal findings of social brain network in Korean children with autism spectrum disorder (ASD) compared with typically developing children (TDC). METHODS: Functional...
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Automated Classification to Predict the Progression of Alzheimer's Disease Using Whole-Brain Volumetry and DTI

Jung WB, Lee YM, Kim YH, Mun CW

OBJECTIVE: This study proposes an automated diagnostic method to classify patients with Alzheimer's disease (AD) of degenerative etiology using magnetic resonance imaging (MRI) markers. METHODS: Twenty-seven patients with subjective memory impairment...
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Disrupted-in-Schizophrenia-1 SNPs and Susceptibility to Schizophrenia: Evidence from Malaysia

Norlelawati AT, Kartini A, Norsidah K, Ramli M, Tariq AR, Wan Rohani WT

OBJECTIVE: Even though the role of the DICS1 gene as a risk factor for schizophrenia is still unclear, there is substantial evidence from functional and cell biology studies that supports...
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Gene Interactions and Structural Brain Change in Early-Onset Alzheimer's Disease Subjects Using the Pipeline Environment

Moon SW, Dinov ID, Zamanyan A, Shi R, Genco A, Hobel S, Thompson P, Toga AW, Alzheimer's Disease Neuroimaging Initiative (ADNI)

OBJECTIVE: This article investigates subjects aged 55 to 65 from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database to broaden our understanding of early-onset (EO) cognitive impairment using neuroimaging and genetics...
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Stress Changes the Spatial Arrangement of Neurons and Glial Cells of Medial Prefrontal Cortex and Sertraline and Curcumin Prevent It

Noorafshan A, Abdollahifar MA, Karbalay-Doust S

OBJECTIVE: The present study explored the three-dimensional spatial arrangements of the neurons and glial cells within the medial prefrontal cortex (mPFC) of rats. METHODS: It evaluated the arrangement for differences after...
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