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Innovations in Clinical Research Design and Conduct in Psychiatry: Shifting to Pragmatic Approaches

Marks DM, Thanaseelan J, Pae CU

  • KMID: 2315808
  • Psychiatry Investig.
  • 2009 Mar;6(1):1-6.
The classically structured clinical trial does not offer enough flexibility to make use of continuously emerging knowledge that is generated as the trial progresses. In this regard, there are consistent...
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The First Report of Fetal Alcohol Effect in a 12 Year-Old Child in Korea

Bhang SY, Ahn DH, Lee YJ, An HY, Ahn JH

  • KMID: 2315816
  • Psychiatry Investig.
  • 2009 Mar;6(1):50-53.
We present the first report of fetal alcohol effect in a 12 year-old child in Korea. The mother had consumed 162 g of alcohol per week continuously during pregnancy. His...
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Symptoms to Use for Diagnostic Criteria of Hwa-Byung, an Anger Syndrome

Min SK, Suh SY, Song KJ

  • KMID: 2315809
  • Psychiatry Investig.
  • 2009 Mar;6(1):7-12.
OBJECTIVE: The aim of this study was to identify the characteristic symptoms which can be used for the diagnosis of hwa-byung, a culture-related anger syndrome in Korea. METHODS: The symptoms...
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An Association Study of the A218C Polymorphism of the Tryptophan Hydroxylase 1 Gene with Eating Disorders in a Korean Population: A Pilot Study

Kim YR, Woo JM, Heo SY, Kim JH, Lim SJ, Yu BH

  • KMID: 2315815
  • Psychiatry Investig.
  • 2009 Mar;6(1):44-49.
OBJECTIVE: We examined the association between the tryptophan hydroxylase 1 (TPH1) gene and eating disorders focusing on obsessionality. METHODS: The sample included 62 women with a lifetime diagnosis of anorexia...
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Deficit in Decision-Making in Chronic, Stable Schizophrenia: From a Reward and Punishment Perspective

Kim YT, Lee KU, Lee SJ

  • KMID: 2315812
  • Psychiatry Investig.
  • 2009 Mar;6(1):26-33.
OBJECTIVE: We compared patients with chronic schizophrenia and normal controls with respect to decision-making ability. Measures were implemented to control for the participants' intelligence levels as well as to ensure...
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Nocturnal Sleep Related with Metabolic Markers in End-Stage Renal Disease Patients Receiving Hemodialysis

Lee JH, Kim SJ, Jung HH

  • KMID: 2315813
  • Psychiatry Investig.
  • 2009 Mar;6(1):34-38.
OBJECTIVE: It has been suggested that oxidative stress and inflammation are associated with the pathophysiology of sleep disorders in end-stage renal disease (ESRD) patients. We examined the relationship of the...
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Alexithymia and Stress Response Patterns among Patients with Depressive Disorders in Korea

Kim HW, Rim HD, Kim JH, Lee SJ

  • KMID: 2315810
  • Psychiatry Investig.
  • 2009 Mar;6(1):13-18.
OBJECTIVE: Alexithymic characteristics may represent cognitive and affective mediators between stressors and stress responses among those with depressive disorders. This study evaluated how alexithymic characteristics, as measured by the Korean...
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G-protein beta3 Subunit Gene 825C/T Polymorphism Is Not Associated with Olanzapine-Induced Weight Gain in Korean Schizophrenic Patients

Park YM, Chung YC, Lee SH, Lee KJ, Kim H, Choi JE, Kang SG, Lee MS, Kim L, Lee HJ

  • KMID: 2315814
  • Psychiatry Investig.
  • 2009 Mar;6(1):39-43.
OBJECTIVE: Weight gain is a possible adverse effect of the use of antipsychotics, and is an important factor for long-term health and treatment compliance. Olanzapine is an atypical antipsychotic known...
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Temporal Changes in Functional Magnetic Resonance Imaging Activation of Heterosexual Couples for Visual Stimuli of Loved Partners

Kim W, Kim S, Jeong J, Lee KU, Ahn KJ, Chung YA, Hong KY, Chae JH

  • KMID: 2315811
  • Psychiatry Investig.
  • 2009 Mar;6(1):19-25.
OBJECTIVE: Previous neuroimaging studies on romantic love have focused on determining how the visual stimuli that serve as a representation of loved ones induce the neural activation patterns of romantic...
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