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Regional Beta Index of Electroencephalography May Differentiate Alzheimer's Disease from Depression

Lee K, Han JW, Kim KW

  • Psychiatry Investig.
  • 2017 Sep;14(5):708-711.
  • doi: 10.4306/pi.2017.14.5.708
Differentiating early Alzheimer's disease (AD) from depression with cognitive impairment is challenging in the elderly. To develop a model for differentiating these two conditions using electroencephalography (EEG), we enrolled 11...
Evidence for Hypothalamus-Pituitary-Adrenal Axis and Immune Alterations at Prodrome of Psychosis in Males

Karanikas , Ntouros E, Oikonomou , Floros G, Griveas I, Garyfallos G

  • Psychiatry Investig.
  • 2017 Sep;14(5):703-707.
  • doi: 10.4306/pi.2017.14.5.703
We aimed to investigate the inflammatory substrate in psychosis by evaluating both the Hypothalamus-Pituitary-Adrenal axis function and immune state at prodrome. This involved the recruitment of Ultra High Risk (UHR)...
Prediction of Treatment Response to Donepezil using Automated Hippocampal Subfields Volumes Segmentation in Patients with Mild Alzheimer's Disease

Um YH, Kim TW, Jeong JH, Seo HJ, Han JH, Hong SC, Lee CU, Lim HK

  • Psychiatry Investig.
  • 2017 Sep;14(5):698-702.
  • doi: 10.4306/pi.2017.14.5.698
Previous studies reported some relationships between donepezil treatment and hippocampus in Alzheimer's disease (AD). However, due to methodological limitations, their close relationships remain unclear. The aim of this study is...
Association between GABA3 Gene Polymorphisms and Attention Deficit Hyperactivity Disorder in Korean Children

Kwon HJ, Kim W, Lim MH

  • Psychiatry Investig.
  • 2017 Sep;14(5):693-697.
  • doi: 10.4306/pi.2017.14.5.693
OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is common disorder of the school-age population. ADHD is familial and genetic studies estimate heritability at 80–90%. The aim of the present study was...
Genome-Wide Supported Risk Variants in MIR137, CACNA1C, CSMD1, DRD2, and GRM3 Contribute to Schizophrenia Susceptibility in Pakistani Population

Fatima A, Farooq M, Abdullah U, Tariq M, Mustafa T, Iqbal M, Tommerup N, Mahmood Baig S

  • Psychiatry Investig.
  • 2017 Sep;14(5):687-692.
  • doi: 10.4306/pi.2017.14.5.687
OBJECTIVE: Schizophrenia is a chronic neuropsychiatric disease afflicting around 1.1% of the population worldwide. Recently, MIR137, CACNA1C, CSMD1, DRD2, and GRM3 have been reported as the most robustly emerging candidates...
No Association between the Polymorphism rs6943555 in the AUTS2 Gene and Personality Traits in Japanese University Students

Narita S, Ikeda K, Nishizawa , Yoshihara , Numajiri M, Onozawa Y, Ohtani N, Iwahashi K

  • Psychiatry Investig.
  • 2017 Sep;14(5):681-686.
  • doi: 10.4306/pi.2017.14.5.681
OBJECTIVE: The autism susceptibility candidate 2 (AUTS2) gene has been implicated in multiple neurological disorders. Several recent studies have revealed that the polymorphism rs6943555 in the AUTS2 gene is broadly...
Genetic Association of the PERIOD3 (Per3) Clock Gene with Bipolar Disorder

Brasil Rocha PM, Campos SB, Neves FS, da Silva Filho HC

  • Psychiatry Investig.
  • 2017 Sep;14(5):674-680.
  • doi: 10.4306/pi.2017.14.5.674
OBJECTIVE: Circadian rhythms have been linked to psychiatric disorders such as Depression and Bipolar Disorder (BD). Given previous evidences of sleep/circadian disturbances as well as the genetic susceptibility for BD,...
Periodic Limb Movements in Sleep is Associated with Increased Mortality

Choi JW, Song JS, Lee YJ, Jeong DU

  • Psychiatry Investig.
  • 2017 Sep;14(5):669-673.
  • doi: 10.4306/pi.2017.14.5.669
OBJECTIVE: To elucidate the association between periodic limb movements in sleep (PLMS) and mortality. METHODS: Nocturnal polysomnographic recordings of 1,344 subjects obtained from 1995 to 2008 were reviewed. The subjects were...
Modest Improvement of Untreated Severe Sleep-Disordered Breathing in the Middle-Aged and Elderly

Jeon HJ, Bang YR, Jeon S, Lee TY, Park HY, Yoon IY

  • Psychiatry Investig.
  • 2017 Sep;14(5):662-668.
  • doi: 10.4306/pi.2017.14.5.662
OBJECTIVE: It has been reported that untreated sleep-disordered breathing (SDB) deteriorates over time, however this remains contentious. The aim of the present study is to evaluate the clinical course of...
Differential Effects of Obesity on Obstructive Sleep Apnea Syndrome according to Age

Lee YJ, Lee YJ, Jeong DU

  • Psychiatry Investig.
  • 2017 Sep;14(5):656-661.
  • doi: 10.4306/pi.2017.14.5.656
OBJECTIVE: To evaluate the effect of obesity on obstructive sleep apnea syndrome (OSAS) by age in relation to anthropometric measurements. METHODS: The medical records of 1,110 participants diagnosed with OSAS were...
Effects of Psychotropic Drugs on Seizure Threshold during Electroconvulsive Therapy

Chi SH, Jeong HG, Lee S, Oh SY, Kim SH

  • Psychiatry Investig.
  • 2017 Sep;14(5):647-655.
  • doi: 10.4306/pi.2017.14.5.647
OBJECTIVE: To analyze the relationship between seizure threshold (ST) and psychotropic drugs in patients treated with ECT. METHODS: We examined clinical data from 43 patients. ST was titrated at each treatment...
Screening Ability of Subjective Memory Complaints, Informant-Reports for Cognitive Decline, and Their Combination in Memory Clinic Setting

Yim SJ, Yi D, Byun MS, Choe YM, Choi HJ, Baek H, Sohn BK, Kim JW, Kim EJ, Lee DY

  • Psychiatry Investig.
  • 2017 Sep;14(5):640-646.
  • doi: 10.4306/pi.2017.14.5.640
OBJECTIVE: This study aimed to compare the accuracy of subjective memory complaints, informant-reports for cognitive declines, and their combination for screening cognitive disorders in memory clinic setting. METHODS: One-hundred thirtytwo cognitively...
Cognitive Stimulation as a Therapeutic Modality for Dementia: A Meta-Analysis

Kim K, Han JW, So Y, Seo J, Kim YJ, Park JH, Lee SB, Lee JJ, Jeong HG, Kim TH, Kim KW

  • Psychiatry Investig.
  • 2017 Sep;14(5):626-639.
  • doi: 10.4306/pi.2017.14.5.626
OBJECTIVE: Although cognitive stimulation (CS) is one of the most popular non-pharmacological interventions for people with dementia, its efficacy is still debatable. We performed a meta-analysis of randomized controlled trials...
The Prevalence of Depression among Patients with the Top Ten Most Common Cancers in South Korea

Park B, Youn S, Yi KK, Lee SY, Lee JS, Chung S

  • Psychiatry Investig.
  • 2017 Sep;14(5):618-625.
  • doi: 10.4306/pi.2017.14.5.618
OBJECTIVE: Among the various psychiatric disorders, depression is a common comorbid condition in cancer patients. Due to the distinct and diverse nature of cancer, the prevalence of depression may be...
Effects of Group Cognitive-Behavioral Therapy in Young Patients in the Early Stage of Psychosis

Kim SW, Jang JE, Lee JY, Lee GY, Yu HY, Park C, Kang HJ, Kim JM, Yoon JS

  • Psychiatry Investig.
  • 2017 Sep;14(5):609-617.
  • doi: 10.4306/pi.2017.14.5.609
OBJECTIVE: To develop a model of group cognitive-behavioral therapy (CBT) for Korean patients with early psychosis. METHODS: The group CBT utilized in the present study consisted of metacognitive training, cognitive restructuring,...
More Resilience in Males with Probable Bipolar Depression than Probable Unipolar Depression among Korean Conscripts

Seo JY, Lee D, Lee D, Cha B, Park CS, Kim BJ, Lee CS, Lee SJ, Ahn IY, Choi JW

  • Psychiatry Investig.
  • 2017 Sep;14(5):603-608.
  • doi: 10.4306/pi.2017.14.5.603
OBJECTIVE: This study investigated whether the resilience of males with probable bipolar depression (PBD) can be strengthened and compared it to that of males with probable unipolar depression (PUD). METHODS: Prospective...
Reliability and Validity of the Korean Version of the General-Food Craving Questionnaire-Trait for Children

Jeong JE, Jung DJ, Kwak M, Yang HK, Lim SY, Lee JH, Yoon KH, Kim DJ

  • Psychiatry Investig.
  • 2017 Sep;14(5):595-602.
  • doi: 10.4306/pi.2017.14.5.595
OBJECTIVE: The General-Food Craving Questionnaire-Trait (G-FCQ-T) is a validated, assessment scale for food craving. The aim of this study was to measure its reliability and validity for Korean children. METHODS: A...
Feasibility of the Korean version of the Bipolar Depression Rating Scale in Adolescents with Early-Onset Bipolar Disorder

Lee DY, Won EK, Choi JW, Min HJ, Kim J, Ha K, Lee Y, Chang JS, Kim Y

  • Psychiatry Investig.
  • 2017 Sep;14(5):585-594.
  • doi: 10.4306/pi.2017.14.5.585
OBJECTIVE: This study explores the feasibility and psychometric properties of the Korean version of the Bipolar Depression Rating Scale (BDRS) in adolescents with Early-onset bipolar disorders. METHODS: Fifty-three participants (aged 13–18)...
Validation of the Korean Depressive Symptom Inventory-Suicidality Subscale

Suh S, Ryu H, Chu C, Hom M, Rogers ML, Joiner T

  • Psychiatry Investig.
  • 2017 Sep;14(5):577-584.
  • doi: 10.4306/pi.2017.14.5.577
OBJECTIVE: The present study aimed to validate a Korean version of the self-report Depressive Symptom Inventory-Suicidality Subscale (DSI-SS). METHODS: 553 South Korean undergraduate students (aged 18–34 years, 74.8% females) completed questionnaires....
Clinical Validation of the Psychotic Depression Assessment Scale, Hamilton Depression Rating Scale-6, and Brief Psychiatric Rating Scale-5: Results from the Clinical Research Center for Depression Study

Park SC, Jang EY, Kim JM, Jun TY, Lee MS, Kim JB, Yim HW, Park YC

  • Psychiatry Investig.
  • 2017 Sep;14(5):568-576.
  • doi: 10.4306/pi.2017.14.5.568
OBJECTIVE: The aim of this study was to validate the psychotic depression assessment scale (PDAS), which includes the six-item melancholia subscale from the Hamilton depression rating scale (HAMD-6) and the...

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