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Treatment-Resistant Depression Entering Remission Following a Seizure during the Course of Repetitive Transcranial Magnetic Stimulation

Kim JW, Bae KY, Kim SW, Kang HJ, Shin IS, Yoon JS, Kim JM

  • Psychiatry Investig.
  • 2016 Jul;13(4):468-471.
  • doi: 10.4306/pi.2016.13.4.468
Major depressive disorder is often resistant to antidepressant treatment. Repetitive transcranial magnetic stimulation (rTMS) has been used in treatment-resistant depression (TRD). Known adverse events of rTMS include transient headache, local...
Blonanserin Augmentation of Atypical Antipsychotics in Patients with Schizophrenia-Who Benefits from Blonanserin Augmentation?: An Open-Label, Prospective, Multicenter Study

Woo YS, Park JE, Kim DH, Sohn I, Hwang TY, Park YM, Jon DI, Jeong JH, Bahk WM

  • Psychiatry Investig.
  • 2016 Jul;13(4):458-467.
  • doi: 10.4306/pi.2016.13.4.458
OBJECTIVE: The purpose of this study was to investigate the efficacy and tolerability of atypical antipsychotics (AAPs) with augmentation by blonanserin in schizophrenic patients. METHODS: aA total of 100 patients with...
Association of CACNA1C Variants with Bipolar Disorder in the Korean Population

Kim S, Cho CH, Geum D, Lee HJ

  • Psychiatry Investig.
  • 2016 Jul;13(4):453-457.
  • doi: 10.4306/pi.2016.13.4.453
OBJECTIVE: Previous studies have suggested an association between CACNA1C and susceptibility of bipolar disorder. In this study, we examined the association of CACNA1C variants with bipolar disorder in the Korean...
Effectiveness of Duloxetine Monotherapy Compared to Combination Therapy with Other Antidepressants in Patients with Major Depressive Disorder: A Short-Term, Retrospective Study

Cheon EJ, Lee JY, Choi JH, Lee YJ, Koo BH

  • Psychiatry Investig.
  • 2016 Jul;13(4):447-452.
  • doi: 10.4306/pi.2016.13.4.447
OBJECTIVE: The purpose of this study was to compare duloxetine monotherapy to combination therapy with other antidepressants in patients with major depressive disorder in a clinical, real world setting. METHODS: An...
Times to Discontinue Antidepressants Over 6 Months in Patients with Major Depressive Disorder

Jung WY, Jang SH, Kim SG, Jae YM, Kong BG, Kim HC, Choe BM, Kim JG, Kim CR

  • Psychiatry Investig.
  • 2016 Jul;13(4):440-446.
  • doi: 10.4306/pi.2016.13.4.440
OBJECTIVE: The aim of the present study was to investigate differences in discontinuation time among antidepressants and total antidepressant discontinuation rate of patients with depression over a 6 month period...
Predictive Validity of Some Common Animal Models of Bipolar Disorder Using Lithium and Lamotrigine Therapy: An Attempt towards a Battery-Based Approach for the Evaluation of Mood Stabilizers

Kumar M, Tripathi C, Verma V, Padhy BM, Meshram GG, Abhilash B

  • Psychiatry Investig.
  • 2016 Jul;13(4):434-439.
  • doi: 10.4306/pi.2016.13.4.434
OBJECTIVE: To determine the predictive validity of some of the commonly employed models of mania and depression using standard drugs i.e. lithium (70 mg/kg) and lamotrigine (5 mg/kg) in male...
Genetic Variations in Attention Deficit Hyperactivity Disorder Subtypes and Treatment Resistant Cases

Unal D, Unal MF, Alikasifoglu M, Cetinkaya

  • Psychiatry Investig.
  • 2016 Jul;13(4):427-433.
  • doi: 10.4306/pi.2016.13.4.427
OBJECTIVE: ObjectiveaaWe evaluated the distribution of alpha-2A adrenergic receptor (ADRA2A) and catechol-o-methyltransferase (COMT) single nucleotide polymorphisms (SNPs) among ADHD subtypes and other homogeneous patient populations including treatment-resistant cases and patients...
Decreased Prolidase Activity in Patients with Posttraumatic Stress Disorder

Demir S, Bulut M, Atli A, Kaplan I, Kaya MC, Bez Y, Özdemir P, Sır A

  • Psychiatry Investig.
  • 2016 Jul;13(4):420-426.
  • doi: 10.4306/pi.2016.13.4.420
OBJECTIVE: Many neurochemical systems have been implicated in the development of Posttraumatic Stress Disorder (PTSD). The prolidase enzyme is a cytosolic exopeptidase that detaches proline or hydroxyproline from the carboxyl...
Association between Medication Adherence and Duration of Outpatient Treatment in Patients with Schizophrenia

Tarutani S, Kikuyama H, Ohta M, Kanazawa T, Okamura T, Yoneda H

  • Psychiatry Investig.
  • 2016 Jul;13(4):413-419.
  • doi: 10.4306/pi.2016.13.4.413
OBJECTIVE: Medication adherence is important in the treatment of schizophrenia, and critical periods during treatment may be associated with relapse. However, the relationship between adherence and duration of outpatient treatment...
Application of Short Screening Tools for Post-Traumatic Stress Disorder in the Korean Elderly Population

Jang YJ, Kang SH, Chung HG, Choi JH, Kim TY, So HS

  • Psychiatry Investig.
  • 2016 Jul;13(4):406-412.
  • doi: 10.4306/pi.2016.13.4.406
OBJECTIVE: Post-traumatic stress disorder (PTSD) is often missed or incorrectly diagnosed in primary care settings. Although brief screening instruments may be useful in detecting PTSD, an adequate validation study has...
Linking an Anxiety-Related Personality Trait to Cardiac Autonomic Regulation in Well-Defined Healthy Adults: Harm Avoidance and Resting Heart Rate Variability

Kao LC, Liu YW, Tzeng NS, Kuo TB, Huang SY, Chang CC, Chang HA

  • Psychiatry Investig.
  • 2016 Jul;13(4):397-405.
  • doi: 10.4306/pi.2016.13.4.397
OBJECTIVE: Anxiety trait, anxiety and depression states have all been reported to increase risks for cardiovascular disease (CVD), possibly through altering cardiac autonomic regulation. Our aim was to investigate whether...
Differences between Impulsive and Non-Impulsive Suicide Attempts among Individuals Treated in Emergency Rooms of South Korea

Lim M, Lee S, Park JI

  • Psychiatry Investig.
  • 2016 Jul;13(4):389-396.
  • doi: 10.4306/pi.2016.13.4.389
OBJECTIVE: A considerable proportion of suicide attempts are the result of sudden desires. Understanding such impulsive suicide attempts is necessary for effective interventions. We evaluated the impulsivity of suicide attempters...
Effects of Early Childhood Peer Relationships on Adolescent Mental Health: A 6- to 8-Year Follow-Up Study in South Korea

Shin KM, Cho SM, Shin YM, Park KS

  • Psychiatry Investig.
  • 2016 Jul;13(4):383-388.
  • doi: 10.4306/pi.2016.13.4.383
OBJECTIVE: Peer relationships are one of the important factors in children's development. The present study examines the relationship between the effects of early peer relationships and adolescent psychological adjustment. METHODS: The...
Internet-Based Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder in Korea

Seol SH, Kwon JS, Kim YY, Kim SN, Shin MS

  • Psychiatry Investig.
  • 2016 Jul;13(4):373-382.
  • doi: 10.4306/pi.2016.13.4.373
OBJECTIVE: Cognitive behavioral therapy (CBT) is regarded as one of the most effective intervention for obsessive-compulsive disorder (OCD). However, many patients remain untreated or inadequately treated due to time or...

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