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Desensitization of Triggers and Urge Reduction for Paruresis: A Case Report

Park H, Kim D, Jang EY, Bae H

  • Psychiatry Investig.
  • 2016 Jan;13(1):161-163.
  • doi: 10.4306/pi.2016.13.1.161
Paruresis is a special type of non-generalized social phobia that involves fear and avoidance of urination in public restrooms. We administered eight 60-minute sessions of desensitization of triggers and urge...
Associations between Serotonergic Genes and Escitalopram Treatment Responses in Patients with Depressive Disorder and Acute Coronary Syndrome: The EsDEPACS Study

Kang HJ, Bae KY, Kim SW, Shin IS, Hong YJ, Ahn Y, Jeong MH, Park SW, Kim YH, Yoon JS, Kim JM

  • Psychiatry Investig.
  • 2016 Jan;13(1):157-160.
  • doi: 10.4306/pi.2016.13.1.157
Genes related to serotonin are associated with responses to treatment for depression. We examined associations between the serotonin transporter (5-HTT) and serotonin 2a receptor (5-HTR2a) genes and responses to treatment...
Brain Activation Patterns Associated with the Effects of Emotional Distracters during Working Memory Maintenance in Patients with Generalized Anxiety Disorder

Park JI, Kim GW, Jeong GW, Chung GH, Yang JC

  • Psychiatry Investig.
  • 2016 Jan;13(1):152-156.
  • doi: 10.4306/pi.2016.13.1.152
Few studies have assessed the neural mechanisms of the effects of emotion on cognition in generalized anxiety disorder (GAD) patients. In this functional MRI (fMRI), we investigated the effects of...
Frontoparietal Cortical Thinning in Respiratory-Type Panic Disorder: A Preliminary Report

Yoon HK, Kang J, Kwon DY, Ham BJ

  • Psychiatry Investig.
  • 2016 Jan;13(1):146-151.
  • doi: 10.4306/pi.2016.13.1.146
OBJECTIVE: Many evidences raise the possibility that the panic disorder (PD) patients with respiratory subtype (RS) may have characteristic structural abnormalities. We aimed to explore the structural differences between PD...
Construction and Validation of Brain MRI Templates from a Korean Normal Elderly Population

Lee H, Yoo BI, Han JW, Lee JJ, Oh SY, Lee EY, Kim JH, Kim KW

  • Psychiatry Investig.
  • 2016 Jan;13(1):135-145.
  • doi: 10.4306/pi.2016.13.1.135
OBJECTIVE: This study aimed to construct a Korean normal elderly brain template (KNE96) using Korean elderly individuals for use in brain MRI studies and to validate it. METHODS: We used high-resolution...
Overexpression of Cell Cycle Proteins of Peripheral Lymphocytes in Patients with Alzheimer's Disease

Kim H, Kwon YA, Ahn IS, Kim S, Kim S, Jo SA, Kim DK

  • Psychiatry Investig.
  • 2016 Jan;13(1):127-134.
  • doi: 10.4306/pi.2016.13.1.127
OBJECTIVE: Biological markers for Alzheimer's disease (AD) will help clinicians make objective diagnoses early during the course of dementia. Previous studies have suggested that cell cycle dysregulation begins earlier than...
Increased Neutrophil/Lymphocyte Ratio in Patients with Depression is Correlated with the Severity of Depression and Cardiovascular Risk Factors

Aydin Sunbul E, Sunbul M, Yanartas O, Cengiz F, Bozbay M, Sari I, Gulec H

  • Psychiatry Investig.
  • 2016 Jan;13(1):121-126.
  • doi: 10.4306/pi.2016.13.1.121
OBJECTIVE: Chronic inflammation is associated with cardiovascular (CV) risk factors and psychiatric disorders. The neutrophil to lymphocyte ratio (NLR) has been investigated as a new biomarker for systemic inflammatory response....
Distribution of Active and Resting Periods in the Motor Activity of Patients with Depression and Schizophrenia

Fasmer OB, Hauge E, Berle JO, Dilsaver S, Oedegaard

  • Psychiatry Investig.
  • 2016 Jan;13(1):112-120.
  • doi: 10.4306/pi.2016.13.1.112
OBJECTIVE: Alterations of activity are prominent features of the major functional psychiatric disorders. Motor activity patterns are characterized by bursts of activity separated by periods with inactivity. The purpose of...
Affective Flattening in Patients with Schizophrenia: Differential Association with Amygdala Response to Threat-Related Facial Expression under Automatic and Controlled Processing Conditions

Lindner C, Dannlowski U, Bauer J, Ohrmann P, Lencer R, Zwitserlood P, Kugel H, Suslow T

  • Psychiatry Investig.
  • 2016 Jan;13(1):102-111.
  • doi: 10.4306/pi.2016.13.1.102
OBJECTIVE: Early neuroimaging studies have demonstrated amygdala hypoactivation in schizophrenia but more recent research based on paradigms with minimal cognitive loads or examining automatic processing has observed amygdala hyperactivation. Hyperactivation...
Parameters of Calcium Metabolism Fluctuated during Initiation or Changing of Antipsychotic Drugs

Milovanovic DR, Stanojevic Pirkovic M, Zivancevic Simonovic S, Matovic M, Djukic Dejanovic S, Jankovic S, Ravanic D, Petronijevic M, Ignjatovic Ristic D, Mladenovic V, Jovanovic , Nikolic Labovic S, Pajovic M, Djokovic D, Petrovic D, Janjic V

  • Psychiatry Investig.
  • 2016 Jan;13(1):89-101.
  • doi: 10.4306/pi.2016.13.1.89
OBJECTIVE: Serum parameters of calcium homeostasis were measured based on previously published evidence linking osteoporotic fractures and/or bone/mineral loss with antipsychotics. METHODS: Prospective, four-week, time-series trial was conducted and study population...
The Hyperactivity of Efferent Auditory System in Patients with Schizophrenia: A Transient Evoked Otoacoustic Emissions Study

Abdul Wahab NA, Wahab S, Abdul Rahman AH, Sidek D, Zakaria MN

  • Psychiatry Investig.
  • 2016 Jan;13(1):82-88.
  • doi: 10.4306/pi.2016.13.1.82
OBJECTIVE: Electrophysiological studies, which are mostly focused on afferent pathway, have proven that auditory processing deficits exist in patients with schizophrenia. Nevertheless, reports on the suppressive effect of efferent auditory...
Copycat Suicide Induced by Entertainment Celebrity Suicides in South Korea

Jang SA, Sung JM, Park JY, Jeon WT

  • Psychiatry Investig.
  • 2016 Jan;13(1):74-81.
  • doi: 10.4306/pi.2016.13.1.74
OBJECTIVE: Throughout the past several years, there have been a number of entertainment celebrity suicides in South Korea. The aim of this study was to investigate the clustering of suicides...
Insomnia in North Korean Refugees: Association with Depression and Post-Traumatic Stress Symptoms

Lee YJ, Jun JY, Lee YJ, Park J, Kim S, Lee SH, Yu SY, Kim SJ

  • Psychiatry Investig.
  • 2016 Jan;13(1):67-73.
  • doi: 10.4306/pi.2016.13.1.67
OBJECTIVE: We investigated the prevalence of insomnia and its clinical characteristics in North Korean refugees. METHODS: North Korean refugees living in South Korea (48 males, 129 females; mean age 38.22+/-12.24 years)...
Characteristics and Psychiatric Symptoms of Internet Gaming Disorder among Adults Using Self-Reported DSM-5 Criteria

Kim NR, Hwang SS, Choi JS, Kim DJ, Demetrovics Z, Kiraly O, Nagygyorgy K, Griffiths , Hyun SY, Youn HC, Choi SW

  • Psychiatry Investig.
  • 2016 Jan;13(1):58-66.
  • doi: 10.4306/pi.2016.13.1.58
OBJECTIVE: The Section III of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) proposed nine diagnostic criteria and five cut-point criteria for Internet Gaming Disorder (IGD). We...
Perspectives on the Happiness of Community-Dwelling Elderly in Korea

Jeon SW, Han C, Lee J, Lim J, Jeong HG, Park MH, Ko YH, Pae CU, Kim SH, Joe SH, Steffens D

  • Psychiatry Investig.
  • 2016 Jan;13(1):50-57.
  • doi: 10.4306/pi.2016.13.1.50
OBJECTIVE: A community survey was performed to investigate the factors and perspectives associated with happiness among the elderly in Korea (> or =60 years). METHODS: Eight hundred volunteers selected from participants...
Factors Associated with Caregiver Burden in Dementia: 1-Year Follow-Up Study

Shim SH, Kang HS, Kim JH, Kim DK

  • Psychiatry Investig.
  • 2016 Jan;13(1):43-49.
  • doi: 10.4306/pi.2016.13.1.43
OBJECTIVE: Dementia symptoms (cognitive function, daily-living function, and neuropsychiatric symptoms) become more serious over time, which is likely to increase caregiver burden. The aim of this study is to investigate...
Impaired Empathic Abilities among Patients with Complex Regional Pain Syndrome (Type I)

Sohn HS, Lee DH, Lee KJ, Noh EC, Choi SH, Jang JH, Kim YC, Kang DH

  • Psychiatry Investig.
  • 2016 Jan;13(1):34-42.
  • doi: 10.4306/pi.2016.13.1.34
OBJECTIVE: The aims of this study were to evaluate differences in empathic abilities between patients with complex regional pain syndrome (CRPS) Type I and healthy control subjects (HCs) and to...
Bipolar Disorder: Role of Inflammation and the Development of Disease Biomarkers

Muneer A

  • Psychiatry Investig.
  • 2016 Jan;13(1):18-33.
  • doi: 10.4306/pi.2016.13.1.18
Bipolar disorder is a severe and enduring psychiatric condition which in many cases starts during early adulthood and follows a relapsing and remitting course throughout life. In many patients the...
Induced Pluripotent Stem Cells as a Novel Tool in Psychiatric Research

Kim S, Kim MK, Oh D, Lee SH, Kim B

  • Psychiatry Investig.
  • 2016 Jan;13(1):8-17.
  • doi: 10.4306/pi.2016.13.1.8
Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) provides a valuable opportunity to study neurodevelopmental and neurodegenerative psychiatric diseases by offering an unlimited source for patient-specific neuronal and...
Three Large-Scale Functional Brain Networks from Resting-State Functional MRI in Subjects with Different Levels of Cognitive Impairment

Joo SH, Lim HK, Lee CU

  • Psychiatry Investig.
  • 2016 Jan;13(1):1-7.
  • doi: 10.4306/pi.2016.13.1.1
Normal aging and to a greater degree degenerative brain diseases such as Alzheimer's disease (AD), cause changes in the brain's structure and function. Degenerative changes in brain structure and decline...

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