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Manic Episode Associated with Mega Cisterna Magna

Turan T, Besirli A, Asdemir A, Ozsoy S, Esel E

  • Psychiatry Investig.
  • 2010 Dec;7(4):305-307.
Mega cisterna magna is a part of "Dandy-Walker Complex" and it is characterized by the enlargement of the cisterna magna, morphologically intact vermis and cerebellar hemispheres. We report a case...
Oseltamivir (Tamiflu) Induced Depressive Episode in a Female Adolescent

Chung S, Joung YS

  • Psychiatry Investig.
  • 2010 Dec;7(4):302-304.
Oseltamivir was developed for prophylactic and therapeutic use against influenza, specifically targeting the viral enzyme's highly-conserved active site. In recent years, there have been case reports of neuropsychiatric events during...
Impaired Set-Shifting Ability in Patients with Eating Disorders, Which Is Not Moderated by Their Catechol-O-Methyltransferase Val158Met Genotype

Kim YR, Kim JE, Kim MH

  • Psychiatry Investig.
  • 2010 Dec;7(4):298-301.
The aim of this study was to examine the set-shifting ability in women with both anorexia nervosa (AN) and bulimia nervosa (BN) and to investigate whether it is contributed by...
Deficits in Facial Emotion Recognition in Schizophrenia: A Replication Study with Korean Subjects

Lee SJ, Lee HK, Kweon YS, Lee CT, Lee KU

  • Psychiatry Investig.
  • 2010 Dec;7(4):291-297.
OBJECTIVE: We investigated the deficit in the recognition of facial emotions in a sample of medicated, stable Korean patients with schizophrenia using Korean facial emotion pictures and examined whether the...
Gender-Specific Association of the Brain-Derived Neurotrophic Factor Gene with Attention-Deficit/Hyperactivity Disorder

Cho SC, Kim HW, Kim BN, Kim JW, Shin MS, Chung S, Cho DY, Jung SW, Yoo HJ, Chung IW, Chung US, Son JW

  • Psychiatry Investig.
  • 2010 Dec;7(4):285-290.
OBJECTIVE: Attention-deficit/hyperactivity disorder (ADHD) is a complex neurodevelopmental disorder with a strong genetic component. Brain-derived neurotrophic factor (BDNF), which participates in the differentiation and survival of dopaminergic and noradrenergic neurons,...
Bone Density in Chronic Schizophrenia with Long-Term Antipsychotic Treatment: Preliminary Study

Lee TY, Chung MY, Chung HK, Choi JH, Kim TY, So HS

  • Psychiatry Investig.
  • 2010 Dec;7(4):278-284.
OBJECTIVE: Decreased bone mineral density has been found in the chronic schizophrenic patients who have been given a long-term administration of antipsychotics. Hyperprolactinemia from the antipsychotics and the negative symptom...
The Genetic Factors Affecting Drinking Behaviors of Korean Young Adults with Variant Aldehyde Dehydrogenase 2 Genotype

Kim SK, Lee SI, Shin CJ, Son JW, Ju G

  • Psychiatry Investig.
  • 2010 Dec;7(4):270-277.
OBJECTIVE: We determined whether aldehyde dehydrogenase 2 (ALDH2) activity alters the way in which drinking behaviors are affected by gene polymorphisms of other alcohol-metabolizing enzymes and serotonin-related proteins. METHODS: Through a...
Thyroid Stimulating Hormone, Cognitive Impairment and Depression in an Older Korean Population

Kim JM, Stewart R, Kim SY, Bae KY, Yang SJ, Kim SW, Shin IS, Yoon JS

  • Psychiatry Investig.
  • 2010 Dec;7(4):264-269.
OBJECTIVE: Associations of thyroid dysfunction with cognitive impairment and depression in late-life have been described but remain controversial. This study aimed to investigate the associations of serum thyroid stimulating hormone...
The Reliability and Validity of the Korean Version of the Structured Interview for Prodromal Syndrome

Jung MH, Jang JH, Kang DH, Choi JS, Shin NY, Kim HS, An SK, Shin MS, Kwon JS

  • Psychiatry Investig.
  • 2010 Dec;7(4):257-263.
OBJECTIVE: The Structured Interview for Prodromal Syndrome (SIPS) from Yale University is intended to diagnose prodromal syndrome of psychosis and to measure the severity of prodromal symptoms. Here, a Korean...
Epigenetic Regulation of BDNF Gene in Response to Stress

Fuchikami , Yamamoto S, Morinobu S, Takei S, Yamawaki S

  • Psychiatry Investig.
  • 2010 Dec;7(4):251-256.
Neuronal plasticity induced by changes in synaptic morphology and function is well known to play a pivotal role in leaning and memory as well as adaptation to stress. It is...
The Role of BDNF as a Mediator of Neuroplasticity in Bipolar Disorder

Grande I, Fries GR, Kunz M, Kapczinski F

  • Psychiatry Investig.
  • 2010 Dec;7(4):243-250.
The cognitive impairment and neuroanatomical changes that takes place among patients with bipolar disorder (BD) patients has been well described. Recent data suggest that changes in neuroplasticity, cell resilience and...
Effects of BDNF Polymorphisms on Antidepressant Action

Tsai SJ, Hong CJ, Liou YJ

  • Psychiatry Investig.
  • 2010 Dec;7(4):236-242.
Evidence suggests that the down-regulation of the signaling pathway involving brain-derived neurotrophic factor (BDNF), a molecular element known to regulate neuronal plasticity and survival, plays an important role in the...
The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment

Lee BH, Kim YK

  • Psychiatry Investig.
  • 2010 Dec;7(4):231-235.
Neurotrophic factors are critical regulators of the formation and plasticity of neuronal networks. Brain-derived neurotrophic factor (BDNF) is abundant in the brain and periphery, and is found in both human...

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