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Dose-volume histogram parameters and patient-reported EPIC-Bowel domain in prostate cancer proton therapy

Bulman GF, Bhangoo RS, DeWees TA, Petersen MM, Thorpe CS, Wong WW, Rwigema JCM, Daniels TB, Keole SR, Schild SE, Vargas CE

Purpose: To analyze rectal dose and changes in quality of life (QOL) measured with the Expanded Prostate and Cancer Index Composite (EPIC) bowel domain in patients being treated for prostate...
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Proton Therapy for Head and Neck Cancer: Current Clinical Applications and Future Direction

Oh D

Intensity-modulated radiation therapy (IMRT) using X-rays is a standard technique implemented for treating head and neck cancer (HN C). Compared to 3D conformal RT, IMRT can significantly reduce the radiation...
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Proton Therapy Review: Proton Therapy from a Medical

Lee SB

With hope and concern, the first Korean proton therapy facility was introduced to the National Cancer Center (NCC) in 2007. It added a new chapter to the history of Korean...
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Status and Prospects in Particle Therapy

Kim JI

  • KMID: 2510117
  • Prog Med Phys.
  • 2020 Sep;31(S1):S80.
Purpose: The charged particle therapy is one of the most advanced modalities for cancer treatment. While most patients have been treated with a proton beam, the clinical centers using a...
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Signal Intensity Measurement of Hydrophone to Position Change of Bragg-Peak Using Iono-Acoustic Wave in Hospital-based Cyclotron

Jeong S, Jeon C, Cho S, Han Y

  • KMID: 2510088
  • Prog Med Phys.
  • 2020 Sep;31(S1):S46.
Purpose: Proton range can be measured using an iono-acoustic wave generated in the Bragg-peak when a proton beam is irradiated on an object. Research on proton range measurement using iono-acoustic...
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A Comparative Study of Deep-Learning based Respiratory Signal Prediction Models for Radiation Therapy: Bi-Directional Long-Short Term Memory

Jung S, Cheon W, Han Y

  • KMID: 2510082
  • Prog Med Phys.
  • 2020 Sep;31(S1):S40.
Purpose: In radiation therapy, the patient’s breathing has a great influence on the treatment of various organs. Especially, proton therapy is more sensitive to the patient’s breathing because it gives...
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A Proof-of-Principle Experiment of Hybrid Prompt Gamma-Positron Emission Tomography System for In Vivo Dose Verification in Proton Therapy

Choi HJ, Cheon BW, Lee HC, Min CH

  • KMID: 2510029
  • Prog Med Phys.
  • 2020 Sep;31(S1):S3.
Purpose: In proton therapy, the uncertainty over determining proton range may adversely affect on the actual dose distribution owing to the steep dose gradient at the distal edge of the...
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The Role of Modern Radiotherapy Technology in the Treatment of Esophageal Cancer

Moon SH, Suh YG

Radiation therapy (RT) has improved patient outcomes, but treatment-related complicationrates remain high. In the conventional 2-dimensional and 3-dimensional conformalRT (3D-CRT) era, there was little room for toxicity reduction because of...
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Proton therapy: the current status of the clinical evidences

Oh D

Proton therapy has the potential advantages of better conformal planning and higher biological effect than photon therapy (X-ray) for targeting tumor tissues. While the energy of a photon passes through...
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Initial Experience of Patient-Specific QA for Wobbling and Line-Scanning Proton Therapy at Samsung Medical Center

Jo K, Ahn SH, Chung K, Cho S, Shin EH, Park S, Hong CS, Kim DH, Lee B, Lee W, Choi DH, Lim DH, Pyo HR, Han Y

PURPOSE: To report the initial experience of patient-specific quality assurance (pQA) for the wobbling and line-scanning proton therapy at Samsung Medical Center. MATERIALS AND METHODS: The pQA results of 89 wobbling...
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Current status of proton therapy techniques for lung cancer

Han Y

Proton beams have been used for cancer treatment for more than 28 years, and several technological advancements have been made to achieve improved clinical outcomes by delivering more accurate and...
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Therapeutic Proton Beam Range Measurement with EBT3 Film and Comparison with Tool for Particle Simulation

Lee N, Kim C, Song MH, Lee SB

PURPOSE: The advantages of ocular proton therapy are that it spares the optic nerve and delivers the minimal dose to normal surrounding tissues. In this study, it developed a solid...
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Stent-graft placement for treatment of massive hemobilia caused by porto-biliary fistula

Takahashi , Sato Y, Hara K, Okuno N, Dejima I, Murata S, Hasegawa T, Chatani S, Onaya H, Inaba Y

Proton beam therapy is a type of radiation therapy and a promising modality for cancer management because it involves few adverse effects and high therapeutic efficacy. However, there are reports...
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Clinical outcome of proton therapy for patients with chordomas

Youn SH, Cho KH, Kim JY, Ha B, Lim YK, Jeong JH, Lee SH, Yoo H, Gwak HS, Shin SH, Hong EK, Kim HK, Hong JB

PURPOSE: To investigate the clinical outcome of proton therapy (PT) in patients with chordoma. MATERIALS AND METHODS: Fifty-eight patients with chordoma treated with PT between June 2007 and December 2015 at...
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Clinical Outcomes of Proton Beam Therapy for Choroidal Melanoma at a Single Institute in Korea

Kim TW, Choi E, Park J, Shin DH, Jung SK, Seok S, Cho KH, Kim JY, Kim DY, Kim TH, Suh YK, Kim YJ, Moon SH

PURPOSE: This study retrospectively evaluated the clinical outcomes and complications of proton beam therapy (PBT) in a single institution in Korea and quantitatively analyzed the change in tumor volume after...
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Radioprotective effects of delphinidin on normal human lung cells against proton beam exposure

Kim HM, Kim SH, Kang BS

BACKGROUND/OBJECTIVES: Exposure of the normal lung tissue around the cancerous tumor during radiotherapy causes serious side effects such as pneumonitis and pulmonary fibrosis. Radioprotectors used during cancer radiotherapy could protect...
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Development of a Real-Time Internal and External Marker Based Gating System for Proton Therapy

Cho J, Cheon W, Ahn S, Lee M, Park HC, Han Y

In respiratory-induced proton therapy, the accuracy of tracking system and beam controlling is more important than photon therapy. Therefore, a high accuracy motion tracking system that can track internal marker...
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Development of an Analytic Software Using Pencil Beam Scanning Proton Beam

Jeong S, Yoon M, Chung K, Han Y, Lim DH, Choi DH

We have developed an analytic software that can easily analyze the spot position and width of proton beam therapy nozzles in a periodic quality assurance. The developed software consists of...
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Correction of Prompt Gamma Distribution for Improving Accuracy of Beam Range Determination in Inhomogeneous Phantom

Park JH, Kim SH, Ku Y, Lee HS, Kim YS, Kim CH, Shin DH, Lee SB, Jeong JH

For effective patient treatment in proton therapy, it is therefore important to accurately measure the beam range. For measuring beam range, various researchers determine the beam range by measuring the...
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Secondary Neutron Dose Measurement for Proton Line Scanning Therapy

Lee C, Lee S, Chung K, Han Y, Chung YH, Kim JS

Proton therapy is increasingly being actively used in the treatment of cancer. In contrast to photons, protons have the potential advantage of delivering higher doses to the cancerous tissue and...
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