- Transient forebrain ischemia induces impairment in cognitive performance prior to extensive neuronal cell death in Mongolian gerbil (Meriones unguiculatus)
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Kondo T, Yoshida S, Nagai H, Takeshita , Mino M, Morioka H, Nakajima T, Kusakabe K, Okada T
- KMID: 2417565
- J Vet Sci.
- 2018 Jul;19(4):505-511.
- doi: 10.4142/jvs.2018.19.4.505
In Mongolian gerbils, bilateral common carotid artery occlusion (BCCAO) for several minutes induces ischemia, due to an incomplete circle of Willis, resulting in delayed neuronal cell death in the Cornet... -
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- The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia
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Lee KE, Cho KO, Choi YS, Kim SY
- KMID: 2388675
- Korean J Physiol Pharmacol.
- 2016 Mar;20(2):185-192.
- doi: 10.4196/kjpp.2016.20.2.185
Ampicillin, a beta-lactam antibiotic, dose-dependently protects neurons against ischemic brain injury. The present study was performed to investigate the neuroprotective mechanism of ampicillin in a mouse model of transient global... -
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- Effects of alpha-Lipoic Acid on Apoptotic Cell Death in Rat Hippocampus Following Transient Forebrain Ischemia-reperfusion Injury
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Ahn HC, Song JH, Kim KS, Yoo SJ
- KMID: 2331506
- J Korean Soc Emerg Med.
- 2007 Apr;18(2):134-142.
PURPOSE: The purpose of this study was to evaluate effect of alpha-lipoic acid on apoptotic cell death in rat hippocampal neuron following transient forebrain ischemia-reperfusion (I/R) injury. METHODS: The four-vessel occlusion... -
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- The Effects of Propofol and Sevoflurane on Neuronal Apoptosis and Bcl-2 Family Protein Expression after Transient Forebrain Ischemia in the Rat
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Ahn BG, Kim WS, Kwon JY
- KMID: 2034400
- Korean J Anesthesiol.
- 2006 Nov;51(5):614-621.
- doi: 10.4097/kjae.2006.51.5.614
BACKGROUND: Anesthetic preconditioning and anesthetics itself have been known to prevent ischemic injury in brain and heart. The purpose of this study was to evaluate the effects of anesthetics and... -
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- A Simple Method for Predicting Hippocampal Neurodegeneration in a Mouse Model of Transient Global Forebrain Ischemia
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Cho KO, Kim SK, Cho YJ, Sung KW, Kim SY
- KMID: 1587393
- Korean J Physiol Pharmacol.
- 2006 Aug;10(4):167-172.
In the present study, we developed a simple method to predict the neuronal cell death in the mouse hippocampus and striatum following transient global forebrain ischemia by evaluating both cerebral... -
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- Immunohistochemical Study on the Distribution of Tumor Endothelial Marker 7 in the Rat Forebrain
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Kang DS, Lee HK, Park HK, Seo IA, Lee KY, Park HT
- KMID: 2092840
- Korean J Anat.
- 2004 Oct;37(5):441-448.
Tumor endothelial marker 7 (TEM7) is a putative transmembrane protein that is highly expressed in the tumor endothelium. In the present study, the expression profile of TEM7 in the rat... -
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- Reduction of Brain Infarct Size and Extracellular Glutamate Accumulation by Dihydrokinate in Spontaneously Hypertensive Rat after Transient Forebrain Ischemia
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Zhang YH, Cai ZH, Chen Y, Li YC
- KMID: 1588443
- J Korean Neurosurg Soc.
- 2004 Oct;36(4):310-316.
No abstract available. -
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- Postischemic Treatment with Aminoguanidine Inhibits Peroxynitrite Production in the Rat Hippocampus Following Transient Forebrain Ischemia
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Choi YS, Yoon YH, Lee JE, Cho KO, Kim SY, Lee SB
- KMID: 1517030
- Korean J Physiol Pharmacol.
- 2004 Feb;8(1):1-5.
Transient forebrain ischemia results in the delayed neuronal death in the CA1 area of the hippocampus. The present study was performed to determine effects of aminoguanidine, a selective iNOS inhibitor,... -
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- Immunocytochemical Localization of Transforming Growth Factor-alpha in the Forebrain of the Rat
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Chung YY, Park SS, Yoon SP, Kim JJ, Moon JS, Jeong SB, Kim HS
- KMID: 1558768
- Korean J Anat.
- 2001 Dec;34(6):589-602.
The distribution of Transforming growth factor-alpha (TGF-alpha) was examined in the rat forebrain by immunocytochemistry. TGF-alpha immunoreactivity was observed in the cerebral hemispheres, thalamus and hypothalamus. Neurons in the olfactory... -
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- Immunohistochemical Localization of Phospholipase D1 in Developing Rat Forebrain
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Choi JS, Min DS, Chung JW, Chun MH, Lee MY
- KMID: 1559034
- Korean J Anat.
- 2001 Aug;34(4):427-434.
Phospholipase D (PLD), one of the intracellular signal transduction enzymes, may play an important role in developing brain. However, the developmental regulation of PLD protein has not been determined. In... -
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- Increase of peroxynitrite production in the rat brain following transient forebrain ischemia
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Kim HJ, Kim SY
- KMID: 1606934
- Korean J Physiol Pharmacol.
- 2001 Jun;5(3):205-212.
It has been proposed that nitric oxide is involved in the pathogenesis of cerebral ischemia-reperfusion. Because superoxide production is also enhanced during reperfusion, the cytotoxic oxidant peroxynitrite could be formed, but it is... -
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- Inhibition of Apoptosis Following Transient Forebrain Ischemia in Gerbils by Intraischemic Mild Hypothermia
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Choi SP, Park KN, You JY, Park SH, Oh DR, Lee WJ, Chun YH, Kim SK
- KMID: 2194314
- J Korean Soc Emerg Med.
- 2001 Mar;12(1):12-20.
BACKGROUND: A brief episode of global forebrain ischemia produces selective and often extensive neuronal loss in several vulnerable brain structures. This cell death does not occur immediately, but is delayed... -
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- Neuroprotective Effects of Propofol, Ketamine and Propofol-ketamine after Transient Forebrain Ischemia in the Rat
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Kwon JY, Jeon JH, Chung KS, Kim IS, Baik SW, Kim HK
- KMID: 2236829
- Korean J Anesthesiol.
- 2001 Feb;40(2):238-243.
- doi: 10.4097/kjae.2001.40.2.238
BACKGROUND: Intravenous anesthetics such as propofol and ketamine have been known to have neuroprotective effects. However, the combination of these drug is not known. This study was conducted to... -
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- Expression of c-fos, p53, Transforming Growth Factor-beta1 and Glial Fibrillary Acidic Protein in Hippocampus Following Transient Forebrain Ischemia in Mongolian Gerbil
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Lee JH, Hur B
- KMID: 2141028
- Korean J Pathol.
- 2001 Feb;35(1):60-70.
BACKGROUND: Recent studies have shown that delayed neuronal death is closely associated with early gene (c-fos or c-jun)-related apoptosis in addition to hypoxia-induced energy deficiency in the hippocampus. METHODS: To... -
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- Effect of sedative dose of propofol on neuronal damage after transient forebrain ischemia in Mongolian gerbils
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Lee SR
- KMID: 1580644
- Korean J Physiol Pharmacol.
- 2000 Feb;4(1):73-79.
This study investigated whether propofol, an intravenous, non-barbiturate anesthetic, could reduce brain damage following global forebrain ischemia. Transient global ischemia was induced in gerbils by occlusion of bilateral carotid arteries for 3 min.... -
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- Expression of Bcl-2 Protein in the Gerbil Hippocampus Following Transient Forebrain Ischemia and Its Modification by Ischemic Preconditioning
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Kim YJ
- KMID: 1964830
- Ewha Med J.
- 1999 Dec;22(4):259-264.
- doi: 10.12771/emj.1999.22.4.259
No abstract available in English. -
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- The Effects of Forebrain Ischemia on Lidocaine-Induced Seizure Threshold in the Rat
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Kim DC, Song HS
- KMID: 2240055
- Korean J Anesthesiol.
- 1999 Sep;37(3):503-509.
- doi: 10.4097/kjae.1999.37.3.503
BACKGROUND: Seizures are common following many cerebral insults, include global and focal ischemia. However, while the mechanism must relate to some change in the relative activities of excitatory and inhibitory... -
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- The Relationship between Cerebral Reperfusion Flow and the Ischemic Histopathologic Damage after Incomplete Forebrain Ischemia in Rat Model
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Hwang TS, Seo JP, Song KJ, Jeong YK, Shin BH, Kim SH
- KMID: 2194555
- J Korean Soc Emerg Med.
- 1999 Jun;10(2):175-182.
BACKGROUND: Experimental data indicate that low-flow reperfusion following prolonged cardiocirculatory arrest may aggravate early cerebral microcirculatory repefusion disorders. We investigated the influence of cerebral repefusion flow change to the ischemic... -
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- Effect of Thiamine Deficiency on the Glial Fibrillary Acidic Protein ( GFAP ) Immunoreacitivity of the Astrogial Cells in Rat Forebrain
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Kim SH, Kim HT, Kim JH, Kim MH, Hwang SJ, Baik TK
- KMID: 2342765
- J Korean Neurol Assoc.
- 1999 Jan;17(1):152-158.
BACKGROUND: Diverse injury to central nervous system results in proliferation and hypertrophy of astrocytes. The hallmark of this response is enhanced expression of the major intermediate filament protein of astrocyte,... -
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- beta-Amyloid Neurotoxicity on Basal Forebrain Cholinergic Neuron Cultures
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Kim DH, Lee JH, Hong HN, Ko JY
- KMID: 1529459
- Korean J Anat.
- 1997 Jun;30(3):225-234.
beta-amyloid[Abeta] peptide consisting of 40 of 42 amino acids peptide is the principal constituent of senile plaques in Alzheimer`s disease. Recently, it has been demonstrated that this peptide and its... -
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