- Application of Thallium Autometallography for Observation of Changes in Excitability of Rodent Brain following Acute Carbon Monoxide Intoxication
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Lee MS, Yang SB, Heo JH
- KMID: 2470189
- J Korean Soc Clin Toxicol.
- 2019 Dec;17(2):66-78.
- doi: 10.22537/jksct.2019.17.2.66
PURPOSE: Thallium (TI+) autometallography is often used for the imaging of neuronal metabolic activity in the rodent brain under various pathophysiologic conditions. The purpose of this study was to apply... -
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- Three-Dimensional Analysis of Mouse Habenula Subnuclei Reveals Reduced Volume and Gene Expression in the Lipopolysaccharide-mediated Depression Model
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Yang E, Kim JY, Yang SH, Lee E, Sun W, Lee HW, Kim H
- KMID: 2468887
- Exp Neurobiol.
- 2019 Dec;28(6):709-719.
- doi: 10.5607/en.2019.28.6.709
The habenula (Hb) is small but important brain structure, anatomically and functionally links the forebrain with the midbrain to modulate various neuropsychiatric functions associated with drug addiction and emotion-associated dysfunctions.... -
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- Gait Ignition Failure in JNPL3 Human Tau-mutant Mice
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Jang H, Ryu JH, Shin KM, Seo NY, Kim GH, Huh YH, Pae AN, Lee KJ
- KMID: 2451075
- Exp Neurobiol.
- 2019 Jun;28(3):404-413.
- doi: 10.5607/en.2019.28.3.404
Cognitive impairments and motor dysfunction are commonly observed behavioral phenotypes in genetic animal models of neurodegenerative diseases. JNPL3 transgenic mice expressing human P301L-mutant tau display motor disturbances with age- and... -
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- Human Neural Stem Cells: Translational Research for Neonatal Hypoxic-Ischemic Brain Injury
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Shin JE, Han J, Lim JH, Eun HS, Park KI
- KMID: 2440695
- Neonatal Med.
- 2019 Feb;26(1):1-16.
- doi: 10.5385/nm.2019.26.1.1
Neonatal hypoxic-ischemic (HI) brain injury is a major cause of neonatal mortality and long-term neurodevelopmental disabilities. Although promising neuroprotective interventions have been studied, the current management of HI brain injury... -
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- A Group of Descending Glutamatergic Neurons Activated by Stress in Corticolimbic Regions Project to the Nucleus Accumbens
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Park JY, Park SY, Kwon H, Song Y, Yun B, Lee Y, Cho Y, Joo A, Han PL
- KMID: 2424733
- Exp Neurobiol.
- 2018 Oct;27(5):387-396.
- doi: 10.5607/en.2018.27.5.387
The nucleus accumbens (NAc) is the major component of the ventral striatum that regulates stress-induced depression. The NAc receives dopaminergic inputs from the ventral tegmental area (VTA), and the role... -
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- Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2
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Kim M, de la Peña JB, Cheong JH, Kim HJ
- KMID: 2420386
- Biomol Ther.
- 2018 Jul;26(4):358-367.
- doi: 10.4062/biomolther.2017.131
Most organisms have adapted to a circadian rhythm that follows a roughly 24-hour cycle, which is modulated by both internal (clock-related genes) and external (environment) factors. In such organisms, the... -
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- Transient forebrain ischemia induces impairment in cognitive performance prior to extensive neuronal cell death in Mongolian gerbil (Meriones unguiculatus)
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Kondo T, Yoshida S, Nagai H, Takeshita , Mino M, Morioka H, Nakajima T, Kusakabe K, Okada T
- KMID: 2417565
- J Vet Sci.
- 2018 Jul;19(4):505-511.
- doi: 10.4142/jvs.2018.19.4.505
In Mongolian gerbils, bilateral common carotid artery occlusion (BCCAO) for several minutes induces ischemia, due to an incomplete circle of Willis, resulting in delayed neuronal cell death in the Cornet... -
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- Aberrant growth of the anterior cranial base relevant to severe midface hypoplasia of Apert syndrome
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Cha BK, Choi DS, Jang IS, Yook HT, Lee SY, Lee SS, Lee SK
- KMID: 2431963
- Maxillofac Plast Reconstr Surg.
- 2018 ;40(1):40.
- doi: 10.1186/s40902-018-0179-8
BACKGROUND: A 9-year-old male showed severe defects in midface structures, which resulted in maxillary hypoplasia, ocular hypertelorism, relative mandibular prognathism, and syndactyly. He had been diagnosed as having Apert syndrome... -
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- Chronic cerebral hypoperfusion and plasticity of the posterior cerebral artery following permanent bilateral common carotid artery occlusion
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Cho KO, Kim SK, Kim SY
- KMID: 2395259
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):643-650.
- doi: 10.4196/kjpp.2017.21.6.643
Vascular dementia (VaD) is a group of heterogeneous diseases with the common feature of cerebral hypoperfusion. To identify key factors contributing to VaD pathophysiology, we performed a detailed comparison of... -
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- The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia
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Lee KE, Cho KO, Choi YS, Kim SY
- KMID: 2388675
- Korean J Physiol Pharmacol.
- 2016 Mar;20(2):185-192.
- doi: 10.4196/kjpp.2016.20.2.185
Ampicillin, a beta-lactam antibiotic, dose-dependently protects neurons against ischemic brain injury. The present study was performed to investigate the neuroprotective mechanism of ampicillin in a mouse model of transient global... -
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- Agmatine protection against chlorpromazine-induced forebrain cortex injury in rats
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Dejanovic , Stevanovic I, Ninkovic M, Stojanovic I, Lavrnja I, Radicevic , Pavlovic M
- KMID: 2363335
- J Vet Sci.
- 2016 Mar;17(1):53-61.
- doi: 10.4142/jvs.2016.17.1.53
This study was conducted to investigate whether agmatine (AGM) provides protection against oxidative stress induced by treatment with chlorpromazine (CPZ) in Wistar rats. In addition, the role of reactive oxygen... -
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- The Centrifugal Influence on Gustatory Neurons in the Nucleus of the Solitary Tract
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Cho YK
- KMID: 2133219
- Int J Oral Biol.
- 2015 Dec;40(4):161-166.
- doi: 10.11620/IJOB.2015.40.4.161
Neuronal activities of taste-responsive cells in the nucleus of the solitary tract (NST) are affected by various physiological factors, such as blood glucose level or sodium imbalance. These phenomena suggest... -
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- Comparison of teratogenecity induced by nano- and micro-sized particles of zinc oxide in cultured mouse embryos
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Jung AY, Jung KY, Lin C, Yon JM, Lee JG, Lee BJ, Yun YW, Nam SY
- KMID: 1807802
- Korean J Vet Res.
- 2015 Jun;55(2):133-139.
- doi: 10.14405/kjvr.2015.55.2.133
The increasing uses of zinc oxide nanoparticles (nZnO) in industrial and personal care products raise possible danger of using nZnO in human. To determine whether ZnO induces size-dependent anomalies during... -
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- Therapeutic Application of Neural Stem Cells for Neonatal Hypoxic-ischemic Brain Injury
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Park KI, Goo K, Jung K, Kim M, Kim IS, Yun S, Lee IS, Shin JE, Yu HY, Eun HS, Kim JE, Namgung R, Lee C
- KMID: 2312947
- Neonatal Med.
- 2013 Aug;20(3):343-353.
Neural stem cells (NSCs) are characterized by a capacity for self-renewal, differentiation into multiple neural cell lineages, and migration toward damaged sites in the central nervous system (CNS). NSCs expanded... -
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- Characterization of nestin expression in astrocytes in the rat hippocampal CA1 region following transient forebrain ischemia
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Cho JM, Shin YJ, Park JM, Kim J, Lee MY
- KMID: 2263105
- Anat Cell Biol.
- 2013 Jun;46(2):131-140.
- doi: 10.5115/acb.2013.46.2.131
Recent studies have suggested that nestin facilitates cellular structural remodeling in vasculature-associated cells in response to ischemic injury. The current study was designed to investigate the potential role of post-ischemic... -
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- The neuroprotective effect of combining sevoflurane and remote ischemic preconditioning in forebrain ischemia model
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Sohn HM, Jeon YT, Hwang JW, Lim YJ, Park HP, Han YR
- KMID: 2046854
- Anesth Pain Med.
- 2013 Apr;8(2):112-116.
BACKGROUND: The aim of this study was to investigate the combining effects of sevoflurane and remote ischemic preconditioning (RIPC) on cell death of pyramidal neurons in the CA1 hippocampus induced... -
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- The neuroprotective effect of colloids in forebrain ischemia model
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Sohn HM, Jeon YT, Hwang JW, Park HP, Lim YJ, Kang SH
- KMID: 1742026
- Anesth Pain Med.
- 2012 Oct;7(4):338-342.
BACKGROUND: The aim of this study was to investigate the neuroprotective effects of colloids (albumin and pentastarch) after forebrain global ischemia in rats. METHODS: Thirty male Sprague-Dawley rats were randomly assigned... -
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- Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury
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Jeong HJ, Kim DW, Kim MJ, Woo SJ, Kim HR, Kim SM, Jo HS, Hwang HS, Kim DS, Cho SW, Won MH, Han KH, Park J, Eum WS, Choi SY
- KMID: 1506222
- Exp Mol Med.
- 2012 Oct;44(10):586-593.
Reactive oxygen species (ROS) contribute to the development of a number of neuronal diseases including ischemia. DJ-1, also known to PARK7, plays an important role in transcriptional regulation, acting as... -
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- The Role of Protein Phosphorylation in the Gustatory Cortex and Amygdala During Taste Learning
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Adaikkan C, Rosenblum
- KMID: 1438548
- Exp Neurobiol.
- 2012 Jun;21(2):37-51.
- doi: 10.5607/en.2012.21.2.37
Protein phosphorylation and dephosphorylation form a major post-translation mechanism that enables a given cell to respond to ever-changing internal and external environments. Neurons, similarly to any other cells, use protein... -
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- Cerebellar maturation ratio of forebrain and brainstem at magnetic resonance imaging in the micropig
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Yi KJ, Kim JY, Lee N, Choi M, Yoon JH, Choi MC
- KMID: 1435818
- Korean J Vet Res.
- 2012 Jun;52(2):83-87.
The study of pigs as a human disease model has been conducted in neuroscience. But the morphological development of pig brain by using MRI is rare. The purpose of this... -
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