- Food Craving, Seeking, and Consumption Behaviors: Conceptual Phases and Assessment Methods Used in Animal and Human Studies
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Lee YH, Kim M, Lee M, Shin D, Ha DS, Park JS, Kim YB, Choi HJ
- KMID: 2459809
- J Obes Metab Syndr.
- 2019 Sep;28(3):148-157.
- doi: 10.7570/jomes.2019.28.3.148
What drives us to eat? It is one of the most fundamental questions in the obesity research field which have been investigated for centuries. Numerous novel in vivo technologies in... -
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- Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride
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Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR
- KMID: 2470106
- Lab Anim Res.
- 2019 Aug;35(2):39-44.
- doi: 10.1186/s42826-019-0006-0
Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and... -
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- Increased CD68/TGFβ Co-expressing Microglia/Macrophages after Transient Middle Cerebral Artery Occlusion in Rhesus Monkeys
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Yeo HG, Hong JJ, Lee Y, Yi KS, Jeon CY, Park J, Won J, Seo J, Ahn YJ, Kim K, Baek SH, Hwang EH, Kim G, Jin YB, Jeong KJ, Koo BS, Kang P, Lim KS, Kim SU, Huh JW, Kim YH, Son Y, Kim JS, Choi CH, Cha SH, Lee SR
- KMID: 2458544
- Exp Neurobiol.
- 2019 Aug;28(4):458-473.
- doi: 10.5607/en.2019.28.4.458
The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in... -
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- Three-axis Modification of Coordinates Enables Accurate Stereotactic Targeting in Non-human Primate Brains of Different Sizes
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Kim HS, Kang GH, Song H, Kim RG, Park JY, Hwang JH, Kim HI
- KMID: 2451077
- Exp Neurobiol.
- 2019 Jun;28(3):425-435.
- doi: 10.5607/en.2019.28.3.425
The brain grows with age in non-human primates (NHPs). Therefore, atlas-based stereotactic coordinates cannot be used directly to target subcortical structures if the size of the animal's brain differs from... -
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- Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling
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Park J, Seo J, Won J, Yeo HG, Ahn YJ, Kim K, Jin YB, Koo BS, Lim KS, Jeong KJ, Kang P, Lee HY, Baek SH, Jeon CY, Hong JJ, Huh JW, Kim YH, Park SJ, Kim SU, Lee DS, Lee SR, Lee Y
- KMID: 2451076
- Exp Neurobiol.
- 2019 Jun;28(3):414-424.
- doi: 10.5607/en.2019.28.3.414
Mitochondria continuously fuse and divide to maintain homeostasis. An impairment in the balance between the fusion and fission processes can trigger mitochondrial dysfunction. Accumulating evidence suggests that mitochondrial dysfunction is... -
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- Evaluation of fecal microbiomes associated with obesity in captive cynomolgus monkeys (Macaca fascicularis)
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Koo BS, Hwang EH, Kim G, Oh H, Son Y, Lee D, Lim KS, Kang P, Lee S, Lee HY, Jeong KJ, Lee Y, Baek SH, Jeon CY, Park SJ, Kim YH, Huh JW, Jin YB, Kim SU, Lee SR, Hong JJ
- KMID: 2448703
- J Vet Sci.
- 2019 May;20(3):e19.
- doi: 10.4142/jvs.2019.20.e19
Microorganisms play important roles in obesity; however, the role of the gut microbiomes in obesity is controversial because of the inconsistent findings. This study investigated the gut microbiome communities in... -
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- Efficient Production of Murine Uterine Damage Model
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Kim YY, Choi BB, Lim JW, Kim YJ, Kim SY, Ku SY
- KMID: 2449243
- Tissue Eng Regen Med.
- 2019 Apr;16(2):119-129.
- doi: 10.1007/s13770-018-0149-3
BACKGROUND: Thin or damaged endometrium causes uterine factor-derived infertility resulting in a failure of embryonic implantation. Regeneration of endometrium is a major issue in gynecology and reproductive medicine. Various types of cells... -
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- Rise of the Visible Monkey: Sectioned Images of Rhesus Monkey
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Chung BS, Jeon CY, Huh JW, Jeong KJ, Har D, Kwack KS, Park JS
- KMID: 2441909
- J Korean Med Sci.
- 2019 Mar;34(8):e66.
- doi: 10.3346/jkms.2019.34.e66
BACKGROUND: Gross anatomy and sectional anatomy of a monkey should be known by students and researchers of veterinary medicine and medical research. However, materials to learn the anatomy of a... -
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- Cell Versus Chemokine Therapy Effects on Cell Mobilization to Chronically Dysfunctional Urinary Sphincters of Nonhuman Primates
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Williams J, Mariya S, Suparto I, Lankford S, Andersson
- KMID: 2431867
- Int Neurourol J.
- 2018 Dec;22(4):260-267.
- doi: 10.5213/inj.1836126.063
PURPOSE: A major question remaining in approaches to tissue engineering and organ replacement is the role of native mobilized native cells in the regeneration process of damaged tissues and organs.... -
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- Mouse models for hepatitis B virus research
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Hwang JR, Park SG
- KMID: 2420820
- Lab Anim Res.
- 2018 Sep;34(3):85-91.
- doi: 10.5625/lar.2018.34.3.85
Hepatitis B virus (HBV) infection remains a major global health problem; indeed, there are 250 million carriers worldwide. The host range of HBV is narrow; therefore, few primates are susceptible... -
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- Does pediatric anesthesia cause brain damage? – Addressing parental and provider concerns in light of compelling animal studies and seemingly ambivalent human data
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Lee JR, Loepke AW
- KMID: 2418525
- Korean J Anesthesiol.
- 2018 Aug;71(4):255-273.
- doi: 10.4097/kja.d.18.00165
Anesthesia facilitates surgery in millions of young children every year. Structural brain abnormalities and functional impairment observed in animals have created substantial concerns among clinicians, parents, and government regulators. Clinical... -
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- Induction of Rhesus Keratinocytes into Functional Ameloblasts by Mouse Embryonic Dental Mesenchyme
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Ruan N, Lin C, Dong X, Hu X, Zhang Y
- KMID: 2410512
- Tissue Eng Regen Med.
- 2018 Apr;15(2):173-181.
- doi: 10.1007/s13770-017-0098-2
Fast progresses in stem cell-based tooth tissue engineering have been achieved in recent years in several animal models including the mouse, rat, dog, and pig. Moreover, various postnatal mesenchymal stem... -
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- Technique for orthotopic liver transplantation in cynomolgus monkeys (Macaca fascicularis)
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Lee KW, Cho CW, Park H, Choi GS, Park JB, Kim SJ
- KMID: 2405333
- Ann Surg Treat Res.
- 2018 Jan;94(1):8-12.
- doi: 10.4174/astr.2018.94.1.8
PURPOSE: Recent studies investigating new strategies to modulate the immune system have utilized animal models of liver transplantation (LT). However, the anhepatic phase (AHP) remains a crucial problem in LT.... -
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- Decoding Saccadic Directions Using Epidural ECoG in Non-Human Primates
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Lee J, Choi H, Lee S, Cho BH, Ahn KH, Kim IY, Lee KM, Jang DP
- KMID: 2439456
- J Korean Med Sci.
- 2017 Aug;32(8):1243-1250.
- doi: 10.3346/jkms.2017.32.8.1243
A brain-computer interface (BCI) can be used to restore some communication as an alternative interface for patients suffering from locked-in syndrome. However, most BCI systems are based on SSVEP, P300,... -
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- Animal Models of Orthopedic Research: A Spinal Fusion Model
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Lee JH, Nam Y, Lee JH
- KMID: 2387793
- J Korean Orthop Assoc.
- 2017 Aug;52(4):344-349.
- doi: 10.4055/jkoa.2017.52.4.344
The incidence of spinal fusion surgery has increased due to an increase in the incidence of degenerative spinal disease or trauma. Moreover, the development of various kinds of implants and... -
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- Molecular Epidemiology of Human Immunodeficiency Virus
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Chin BS
- KMID: 2375093
- Infect Chemother.
- 2017 Mar;49(1):1-9.
- doi: 10.3947/ic.2017.49.1.1
During the evolution of human immunodeficiency virus (HIV), transmissions between humans and primates resulted in multiple HIV lineages in humans. This evolution has been rapid, giving rise to a complex... -
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- Development and Evaluation of Acellular Dermal Matrix Originated from Transgenic Porcine Skin for Primates Skin Graft
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Lee KW, Choi GS, Kim MJ, Lee JS, Yoon H, Chun W
- KMID: 2361631
- J Korean Burn Soc.
- 2016 Dec;19(2):82-87.
- doi: 10.0000/jkbs.2016.19.2.82
This study was performed to compare the healing quality of the allogenic acellular dermal matix (ADM) and xenogenic ADM combined with autologous split thicknessskin graft. Xenogenic ADM was obtained from... -
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- Structural Variation of Alu Element and Human Disease
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Kim S, Cho CS, Han K, Lee J
- KMID: 2353657
- Genomics Inform.
- 2016 Sep;14(3):70-77.
- doi: 10.5808/GI.2016.14.3.70
Transposable elements are one of major sources to cause genomic instability through various mechanisms including de novo insertion, insertion-mediated genomic deletion, and recombination-associated genomic deletion. Among them is Alu element... -
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- Use of Nonhuman Primates for the Development of Bioengineered Female Reproductive Organs
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Yun JW, Kim YY, Ahn JH, Kang BC, Ku SY
- KMID: 2382932
- Tissue Eng Regen Med.
- 2016 Aug;13(4):323-334.
- doi: 10.1007/s13770-016-9091-4
Nonhuman primates (NHPs) have been widely used in reproductive biology, neuroscience, and drug development since a number of primate species are phylogenetically close to humans. In this review, we summarize... -
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- Zika Virus Infection
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Yoon HJ, Yeom JS
- KMID: 2345577
- Korean J Med.
- 2016 Aug;91(1):5-11.
- doi: 10.3904/kjm.2016.91.1.5
Zika virus was first isolated in from nonhuman primate in 1947. It is in the genus Flavivirus, closely related to other flavivirus like Dengue, West Nile, Yellow fever and Japanese... -
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