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Preclinical Assessment of the Anticancer Drug Response of Plexiform Neurofibroma Tissue Using Primary Cultures

Jiang W, Mautner VF, Friedrich , Kluwe L

BACKGROUND AND PURPOSE: Individualized drug testing for tumors using a strategy analogous to antibiotic tests for infectious diseases would be highly desirable for personalized and individualized cancer care. METHODS: Primary cultures...
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Expression and Activity of the Na-K ATPase in Ischemic Injury of Primary Cultured Astrocytes

Kim MJ, Hur J, Ham IH, Yang HJ, Kim Y, Park S, Cho YW

Astrocytes are reported to have critical functions in ischemic brain injury including protective effects against ischemia-induced neuronal dysfunction. Na-K ATPase maintains ionic gradients in astrocytes and is suggested as an...
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Effects of Hypoxia on the Ubiquitin-proteasome System in Primary Cortical Neuronal Cell Cultures

Yang SJ, Kim MJ, Jeong HJ, Kim GC, Gil YG, Kim KR, Kim H

  • KMID: 1481577
  • Korean J Phys Anthropol.
  • 2008 Mar;21(1):21-29.
The ubiquitin-proteasome system is crucial in maintaining cellular growth and metabolism. Dysfunction of this system may contribute to neurodegenerative diseases, such as Parkinson's disease. But its effects on primary neurons...
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The inductive capacity of primary cultured oral mucosal keratinocytes in skin wound healing of athymic nude mice

Kim HS, Kim NH, Kim J, Cha IH

  • KMID: 1961096
  • J Korean Assoc Oral Maxillofac Surg.
  • 2004 Aug;30(4):308-315.
AIM: The aim of this study was to investigate the mechanism of promoted skin wound healing in skin defects with primary cultured oral mucosal keratinocytes. MATERIALS AND METHODS: Thirty adult female...
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Effects of Irradiation on Migration Ability of Malignant Glioma Primary Culture Cells

Ryu HH, Lee YH, Jeong YI, Sun HS, Jung S, Kim IY, Kang SS

  • KMID: 2172364
  • Chonnam Med J.
  • 2003 Mar;39(1):14-19.
Human malignant gliomas are highly lethal neoplasms. Postoperative involved-field radiotherapy is one of the most important therapeutic measures. Most relapses originate from the close vicinity of the irradiated target field....
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Study for the Ureteral Reconstruction with Tissue Engineering Using Poly (glycolide/epsilon-caprolactone) Scaffold-1

Bahk JY, Hyun JS, Kim MO, Kwon IK, Park KD, Kim YH

  • KMID: 2292327
  • Korean J Urol.
  • 2001 Apr;42(4):371-378.
PURPOSE: Transplantation is one modality saving human life. But not only lack of the living or cadaveric human organs but also immunologic problems or some ethical situations limit transplantation in...
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Regulation of FSH Gene Expression and Release in Cultured Rat Anterior Pituitary Cells

Cheon MS, Park DB, Park YB, Kam KY, Ryu KZ

  • KMID: 2199610
  • J Korean Soc Endocrinol.
  • 2000 Jun;15(2):179-189.
BACKGROUND: FSH is a heterodimeric glycoprotein and is composed of alpha and beta subunits. alpha subunit is common to FSH and LH, while an unique beta subunit determines the biological...
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Differential effect of homocysteic acid and cysteic acid on changes of inositol phosphates and (Ca2+)i in rat cerebellar granule cells

Kim WK, Pae YS

  • KMID: 2071522
  • Korean J Physiol Pharmacol.
  • 1998 Feb;2(1):41-48.
The present study was undertaken to characterize homocysteic acid (HCA)-and cysteic acid (CA)mediated formation of inositol phosphates (InsP) in primary culture of rat cerebellar granule cells. HCA and CA stimulated InsP formation in...
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Secretory response of cultured acinar cells of rat pancreas to cholecystokinin

Kim H, Kim KH

To determine the adequate models for studying the functions of pancreatic acinar cells, secretory responses to CCK and to CCK receptor antagonist, L-364, 718 were examined in freshly isolated cells...
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In Vitro Intrinsic Radiosensitivity Of Human Squamous Cell Carcinoma in Primary Culture

Choi EK, Yang KM, Yi BY, Chang H, Kim SY, Nam JH, Yu ES, Lee I

  • KMID: 2196830
  • J Korean Soc Ther Radiol.
  • 1994 Feb;12(1):27-32.
There are a number of reports suggesting that there may be a correlation between the clinical response to radiotherapy in various tumors and the clonogenic survival of cell lines derived...
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