- New Perspectives in Pediatric Nonalcoholic Fatty Liver Disease: Epidemiology, Genetics, Diagnosis, and Natural History
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Ko JS
- KMID: 2462089
- Pediatr Gastroenterol Hepatol Nutr.
- 2019 Nov;22(6):501-510.
- doi: 10.5223/pghn.2019.22.6.501
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in children. The global prevalence of pediatric NAFLD from general populations is 7.6%. In obese children,... -
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- NR3C1 Polymorphisms for Genetic Susceptibility to Schizophrenia
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Park JS, Lee SM, Kim JW, Kang WS
- KMID: 2469520
- Korean J Biol Psychiatry.
- 2019 Oct;26(2):88-93.
- doi: 10.0000/kjbp.2019.26.2.88
OBJECTIVES: Psychological stress has been known to increase the risk of schizophrenia. Because stress responses are mainly mediated by cortisol, the action of the glucocorticoid receptors (Nuclear Receptor Subfamily 3... -
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- The Interplay between Host Immunity and Respiratory Viral Infection in Asthma Exacerbation
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Hossain FM, Choi JY, Uyangaa E, Park SO, Eo SK
- KMID: 2461195
- Immune Netw.
- 2019 Oct;19(5):e31.
- doi: 10.4110/in.2019.19.e31
Asthma is one of the most common and chronic diseases characterized by multidimensional immune responses along with poor prognosis and severity. The heterogeneous nature of asthma may be attributed to... -
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- Analysis of vitamin D-binding protein (VDBP) gene polymorphisms in Korean women with and without endometriosis
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Cho MC, Kim JH, Jung MH, Cho IA, Jo HC, Shin JK, Lee SA, Choi WJ, Lee JH
- KMID: 2458501
- Clin Exp Reprod Med.
- 2019 Sep;46(3):132-139.
- doi: 10.5653/cerm.2019.00122
OBJECTIVE: Vitamin D-binding protein (VDBP) mediates various biological processes in humans. The goal of this study was to investigate whether VDBP gene polymorphisms could predispose Korean women to endometriosis. METHODS: We... -
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- Effects of Obesity and Family History of Diabetes on the Association of CETP rs6499861 with HDL-C Level in Korean Populations
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Sull JW, Kim S, Jee SH
- KMID: 2458390
- J Lipid Atheroscler.
- 2019 Sep;8(2):252-257.
- doi: 10.12997/jla.2019.8.2.252
OBJECTIVES: The aim of this study was to examine the associations of cholesterol ester transfer protein (CETP) rs6499861 and rs12708980 with high-density lipoprotein cholesterol (HDL-C) considering obesity and family history... -
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- Polymorphisms of the BARX1 and ADAMTS17 Locus Genes in Individuals With Gastroesophageal Reflux Disease
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Argyrou A, Legaki E, Koutserimpas C, Gazouli M, Papaconstantinou I, Gkiokas G, Karamanolis G
- KMID: 2454642
- J Neurogastroenterol Motil.
- 2019 Jul;25(3):436-441.
- doi: 10.5056/jnm18183
BACKGROUND/AIMS: Gastroesophageal reflux disease (GERD) represents a common condition having a substantial impact on the patients' quality of life, as well as the health system. According to many studies, the... -
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- Associations among Genetic Variants and Intracranial Aneurysm in a Chinese Population
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Li B, Hu C, Liu J, Liao X, Xun J, Xiao M, Yan J
- KMID: 2450405
- Yonsei Med J.
- 2019 Jul;60(7):651-658.
- doi: 10.3349/ymj.2019.60.7.651
PURPOSE: Genome-wide association studies (GWAS) have revealed that common variants on or near EDNRA, HDAC9, SOX17, RP1, CDKN2B-AS1, and RBBP8 genes are associated with intracranial aneurysm (IA) in European or... -
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- The Correlation between IL-1β-C31T Gene Polymorphism and Susceptibility to Breast Cancer
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Eras N, Daloglu FT, Çolak T, Guler M, Akbas E
- KMID: 2450116
- J Breast Cancer.
- 2019 Jun;22(2):210-218.
- doi: 10.4048/jbc.2019.22.e27
PURPOSE: Interleukin-1 beta (IL-1β), a pro-inflammatory cytokine, has been shown to influence breast cancer susceptibility. The relationship between its risk of breast cancer and IL-1β-C31T polymorphism has been demonstrated, but... -
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- Predicting Behavior Problems in Korean Preschoolers: Interactions of the SLC6A4 Gene and Maternal Negative Affectivity
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Ha J, Jun HJ, Shin H, Chung IJ, Park E, Min SK, Kim E
- KMID: 2456723
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):200-210.
- doi: 10.9758/cpn.2019.17.2.200
OBJECTIVE: This study aimed to investigate whether maternal negative affectivity (MNA) moderates the effect of genetic polymorphism of SLC6A4 on behavior problems in children. METHODS: Study participants comprised 143 preschoolers and... -
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- Effect of PTEN Polymorphism on the Development of Hepatitis B Virus-associated Hepatocellular Carcinoma
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Kim SS, Eun JW, Cho HJ, Lee HY, Seo CW, Lee GH, Yoon SY, Noh CK, Cho SW, Cheong JY
- KMID: 2448276
- J Liver Cancer.
- 2019 Mar;19(1):46-54.
- doi: 10.17998/jlc.19.1.46
BACKGROUND/AIMS: Phosphatase and tensin homolog (PTEN) is a known tumor suppressor gene that is downregulated in hepatocellular carcinoma (HCC). Here, we investigated the association between single nucleotide polymorphisms (SNPs) of... -
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- Genetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea
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Nam H, Kim YY, Kim B, Yoon WK, Kim HC, Suh JG
- KMID: 2459310
- Lab Anim Res.
- 2018 Dec;34(4):311-316.
- doi: 10.5625/lar.2018.34.4.311
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and... -
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- Metabolic Syndrome Prediction Using Machine Learning Models with Genetic and Clinical Information from a Nonobese Healthy Population
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Choe EK, Rhee H, Lee S, Shin E, Oh SW, Lee JE, Choi SH
- KMID: 2439221
- Genomics Inform.
- 2018 Dec;16(4):e31.
- doi: 10.5808/GI.2018.16.4.e31
The prevalence of metabolic syndrome (MS) in the nonobese population is not low. However, the identification and risk mitigation of MS are not easy in this population. We aimed to... -
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- No Association between Polymorphisms of Vitamin D and Oxytocin Receptor Genes and Autistic Spectrum Disorder in a Sample of Turkish Children
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Bozdogan S, Kutuk MO, Tufan E, Altıntaş Z, Temel GO, Toros F
- KMID: 2428971
- Clin Psychopharmacol Neurosci.
- 2018 Nov;16(4):415-421.
- doi: 10.9758/cpn.2018.16.4.415
OBJECTIVE: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairment in social skills and communication with repetitive behaviors. Etiology is still unclear although it is thought to develop... -
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- Association between genetic polymorphisms and external apical root resorption: A systematic review and meta-analysis
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Nowrin SA, Jaafar S, Ab Rahman , Basri R, Alam MK, Shahid F
- KMID: 2427777
- Korean J Orthod.
- 2018 Nov;48(6):395-404.
- doi: 10.4041/kjod.2018.48.6.395
OBJECTIVE: To date, only a few studies have investigated the relationships between genetic polymorphisms and external apical root resorption (EARR). Hence, the aim of this systematic review was to explore... -
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- Association of a genetic polymorphism of IL1RN with risk of acute pancreatitis in a Korean ethnic group
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Park JW, Choi JS, Han KJ, Lee SH, Kim EJ, Cho JH
- KMID: 2426394
- Korean J Intern Med.
- 2018 Nov;33(6):1103-1110.
- doi: 10.3904/kjim.2017.133
BACKGROUND/AIMS: Several epidemiological studies have validated the association of interleukin gene polymorphisms with acute pancreatitis (AP) in different populations. However, there have been few studies in Asian ethnic groups. We... -
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- Nonsteroidal anti-inflammatory drug hypersensitivity in the Asia-Pacific
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Thong BY
- KMID: 2423989
- Asia Pac Allergy.
- 2018 Oct;8(4):e38.
- doi: 10.5415/apallergy.2018.8.e38
Nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity reactions (HSRs) are often nonimmunologically mediated reactions which present with immediate HSR type manifestations. These are mediated by cyclooxygenase inhibition resulting in shunting towards the... -
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- Predictive Factors for Improvement of Atrophic Gastritis and Intestinal Metaplasia: A Long-term Prospective Clinical Study
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Hwang YJ, Kim N, Yun CY, Kwon MG, Baek SM, Kwon YJ, Lee HS, Lee JB, Choi YJ, Yoon H, Shin CM, Park YS, Lee DH
- KMID: 2439829
- Korean J Helicobacter Up Gastrointest Res.
- 2018 Sep;18(3):186-197.
- doi: 10.7704/kjhugr.2018.18.3.186
BACKGROUND/AIMS: To investigate the predictive factors for improvement of atrophic gastritis (AG) and intestinal metaplasia (IM). MATERIALS AND METHODS: A total of 778 subjects were prospectively enrolled and followed up for... -
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- Association of Genetic Polymorphisms with Atopic Dermatitis, Clinical Severity and Total IgE: A Replication and Extended Study
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Kim JH, Lee SY, Kang MJ, Yoon J, Jung S, Cho HJ, Kim HB, Hong SJ
- KMID: 2421674
- Allergy Asthma Immunol Res.
- 2018 Jul;10(4):397-405.
- doi: 10.4168/aair.2018.10.4.397
PURPOSE: Atopic dermatitis (AD) is a common and chronic inflammatory skin disease affecting up to 20% of children and 3% of adults worldwide. Although previous reports including genome-wide association study... -
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- How Different Parts of the World Provide New Insights Into Food Allergy
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Tham EH, Leung DY
- KMID: 2421667
- Allergy Asthma Immunol Res.
- 2018 Jul;10(4):290-299.
- doi: 10.4168/aair.2018.10.4.290
The prevalence and patterns of food allergy are highly variable in different parts of the world. Differences in food allergy epidemiology may be attributed to a complex interplay of genetic,... -
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- Influence of CYP2D6 Polymorphism on the Pharmacokinetic/Pharmacodynamic Characteristics of Carvedilol in Healthy Korean Volunteers
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Jung E, Ryu S, Park Z, Lee JG, Yi JY, Seo DW, Lee J, Jeong HS, Kim JM, Oh WY
- KMID: 2414573
- J Korean Med Sci.
- 2018 Jul;33(27):e182.
- doi: 10.3346/jkms.2018.33.e182
BACKGROUND: Carvedilol is commonly used to treat hypertension as a β- and α1-adrenoreceptor blocker, but it is metabolized by CYP2D6, and CYP2D6*10 allele is dominant in Asian population. The objective... -
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