- Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches
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Thein W, Po WW, Choi WS, Sohn UD
- KMID: 2517153
- Biomol Ther.
- 2021 Jul;29(4):353-364.
- doi: 10.4062/biomolther.2021.086
The gastrointestinal (GI) tract is a series of hollow organs that is responsible for the digestion and absorption of ingested foods and the excretion of waste. Any changes in the... -
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- The Altered Signaling on EFS-Induced Colon Contractility in Diabetic Rats
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Thein W, Po WW, Kim DM, Sohn UD
- KMID: 2503472
- Biomol Ther.
- 2020 Jul;28(4):328-336.
- doi: 10.4062/biomolther.2019.181
Diabetes mellitus affects the colonic motility developing gastrointestinal symptoms, such as constipation. The aim of the study was to examine the role of intracellular signaling pathways contributing to colonic dysmotility... -
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- Fluoxetine Simultaneously Induces Both Apoptosis and Autophagy in Human Gastric Adenocarcinoma Cells
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Po WW, Thein W, Khin PP, Khing TM, Han KWW, Park CH, Sohn UD
- KMID: 2507833
- Biomol Ther.
- 2020 Mar;28(2):202-210.
- doi: 10.4062/biomolther.2019.103
Fluoxetine is used widely as an antidepressant for the treatment of cancer-related depression, but has been reported to also have anti-cancer activity. In this study, we investigated the cytotoxicity of... -
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- Benzyl Isothiocyanate-Induced Cytotoxicity via the Inhibition of Autophagy and Lysosomal Function in AGS Cells
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Po WW, Choi WS, Khing TM, Lee JY, Lee JH, Bang JS, Min YS, Jeong JH, Sohn UD
- KMID: 2531000
- Biomol Ther.
- 2022 Jul;30(4):348-359.
- doi: 10.4062/biomolther.2022.019
Gastric adenocarcinoma is among the top causes of cancer-related death and is one of the most commonly diagnosed carcinomas worldwide. Benzyl isothiocyanate (BITC) has been reported to inhibit the gastric... -
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