- β-Sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition in amyloid protein precursor/presenilin 1 mice
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Ye JY, Li L, Hao QM, Qin Y, Ma CS
- KMID: 2466568
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):39-46.
- doi: 10.4196/kjpp.2020.24.1.39
Alzheimer's disease (AD) is the most common neurodegenerative disorder causing dementia worldwide, and is mainly characterized by aggregated β-amyloid (Aβ). Increasing evidence has shown that plant extracts have the potential... -
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- Role Identification of Passiflora Incarnata Linnaeus: A Mini Review
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Kim M, Lim HS, Lee HH, Kim TH
- KMID: 2400250
- J Menopausal Med.
- 2017 Dec;23(3):156-159.
- doi: 10.6118/jmm.2017.23.3.156
Some species of traditional herbal medicine has a history of use, most traditional natural herbs have been used for various diseases such as diabetes, hypertension, and obesity. Among them, Passiflora... -
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- The Clinical Effects of Dendropanax Morbifera on Postmenopausal Symptoms: Review Article
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Kim M, Park YJ, Lim HS, Lee HH, Kim TH, Lee B
- KMID: 2400249
- J Menopausal Med.
- 2017 Dec;23(3):146-155.
- doi: 10.6118/jmm.2017.23.3.146
Postmenopausal women aged 50s generally experience gradual changes in body such as decline in antioxidant and estrogen levels as the body ages. To overcome these aging-associated changes, the needs for... -
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- Gintonin, an exogenous ginseng-derived LPA receptor ligand, promotes corneal wound healing
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Kim HJ, Kim JY, Lee BH, Choi SH, Rhim H, Kim HC, Ahn SY, Jeong SW, Jang M, Cho IH, Nah SY
- KMID: 2412457
- J Vet Sci.
- 2017 Sep;18(3):387-397.
- doi: 10.4142/jvs.2017.18.3.387
Ginseng gintonin is an exogenous ligand of lysophosphatidic acid (LPA) receptors. Accumulating evidence shows LPA helps in rapid recovery of corneal damage. The aim of this study was to evaluate... -
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- Inhibition of Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells by the fruits of Tribulus terrestris L. extracts
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Lee HA, Yoo JH, Chung Y, Kim O
- KMID: 2394599
- J Biomed Transl Res.
- 2017 Sep;18(3):121-124.
- doi: 10.12729/jbtr.2017.18.3.121
Infection with Helicobacter pylori leads to gastritis, peptic ulcers and gastric cancer. Moreover, when the gastric mucosa is exposed to H. pylori, gastric mucosal inflammatory cytokine interleukin-8 (IL-8) and reactive... -
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- Antibacterial activity of essential oil from lavender (Lavandula angustifolia) against pet turtle-borne pathogenic bacteria
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Hossain S, Heo H, De Silva B, Wimalasena SHMP, Pathirana , Heo GJ
- KMID: 2391091
- Lab Anim Res.
- 2017 Sep;33(3):195-201.
- doi: 10.5625/lar.2017.33.3.195
Pet turtles are well-known to harbor an array of bacterial pathogens which can cause zoonotic infections in humans as well as opportunistic infections in the turtles itself. Essential oils are... -
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- Heme Oxygenase-1 Induction and Anti-inflammatory Actions of Atractylodes macrocephala and Taraxacum herba Extracts Prevented Colitis and Was More Effective than Sulfasalazine in Preventing Relapse
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Han KH, Park JM, Jeong M, Han YM, Go EJ, Park J, Kim H, Han JG, Kwon O, Hahm KB
- KMID: 2389354
- Gut Liver.
- 2017 Sep;11(5):655-666.
- doi: 10.5009/gnl16496
BACKGROUND/AIMS: In inflammatory bowel disease (IBD), repeated bouts of remission and relapse occur in patients and can impose a risk of colitis-associated cancer. We hypothesized that plant extracts of Atractylodes... -
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- Efficacy of horse chestnut leaf extract ALH-L1005 as a matrix metalloproteinase inhibitor in ligature-induced periodontitis in canine model
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Kim SE, Kim TH, Park SA, Kim WT, Park YW, Ahn JS, Jeong M, Kim MY, Seo K
- KMID: 2412578
- J Vet Sci.
- 2017 Jun;18(2):245-251.
- doi: 10.4142/jvs.2017.18.2.245
Matrix metalloproteinases (MMPs) are the main proteinases associated with periodontal tissue destruction and remodeling. Therefore, inhibition of host-derived MMPs has a key role in the prevention and reduction of periodontitis... -
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- Neuronal maturation in the hippocampal dentate gyrus via chronic oral administration of Artemisa annua extract is independent of cyclooxygenase 2 signaling pathway in diet-induced obesity mouse model
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Baek HK, Kim PS, Song JA, Choi DH, Kim DE, Oh SI, Park SK, Kim SJ, Song KD, Hwang IK, Seo HS, Yi SS
- KMID: 2412564
- J Vet Sci.
- 2017 Jun;18(2):119-127.
- doi: 10.4142/jvs.2017.18.2.119
Recently, we reported that Artemisia annua (AA) has anti-adipogenic properties in vitro and in vivo. Reduction of adipogenesis by AA treatment may dampen systemic inflammation and protect neurons from cytokine-induced... -
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- In Vitro Anti-Malassezia Activity of Castanea crenata Shell and Oil-Soluble Glycyrrhiza Extracts
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Han SH, Hur MS, Kim MJ, Jung WH, Park M, Kim JH, Shin HJ, Choe YB, Ahn KJ, Lee YW
- KMID: 2378532
- Ann Dermatol.
- 2017 Jun;29(3):321-326.
- doi: 10.5021/ad.2017.29.3.321
BACKGROUND: A new shampoo with anti-Malassezia properties obtained from various plants is required to provide seborrheic dermatitis patients with a wider range of treatment options. OBJECTIVE: The aim of this study... -
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- Therapeutic Potential of Medicinal Plants and Their Constituents on Lung Inflammatory Disorders
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Kim HP, Lim H, Kwon YS
- KMID: 2375028
- Biomol Ther.
- 2017 Mar;25(2):91-104.
- doi: 10.4062/biomolther.2016.187
Acute bronchitis and chronic obstructive pulmonary diseases (COPD) are essentially lung inflammatory disorders. Various plant extracts and their constituents showed therapeutic effects on several animal models of lung inflammation. These... -
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- Aristolochia manshuriensis Kom ethyl acetate extract protects against high-fat diet-induced non-alcoholic steatohepatitis by regulating kinase phosphorylation in mouse
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Kwak DH, Kim JS, Chang KT, Choo YK
- KMID: 2413126
- J Vet Sci.
- 2016 Sep;17(3):279-287.
- doi: 10.4142/jvs.2016.17.3.279
Aristolochia manshuriensis Kom (AMK) is an herb used as a traditional medicine; however, it causes side effects such as nephrotoxicity and carcinogenicity. Nevertheless, AMK can be applied in specific ways... -
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- PMK-S005 Alleviates Age-Related Gastric Acid Secretion, Inflammation, and Oxidative Status in the Rat Stomach
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Choi YJ, Kim N, Lee JY, Nam RH, Suh JH, Lee SM, Ham MH, Jo HJ, Shim YK, Park YH, Lee JC, Choi YJ, Lee HS, Lee DH
- KMID: 2412072
- Gut Liver.
- 2016 Sep;10(5):749-756.
- doi: 10.5009/gnl15584
BACKGROUND/AIMS: The aim of this study was to evaluate the effect of the synthetic S-allyl-l-cysteine (SAC) PMK-S005 on gastric acid secretion, inflammation, and antioxidant enzymes in aging rats. METHODS: The rats... -
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- Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking
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Sahoo M, Jena L, Rath SN, Kumar S
- KMID: 2353661
- Genomics Inform.
- 2016 Sep;14(3):96-103.
- doi: 10.5808/GI.2016.14.3.96
The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for... -
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- Electron Microscopic Alterations in Pediculus humanus capitis Exposed to Some Pediculicidal Plant Extracts
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Akkad DM, El-Gebaly , Yousof HA, Ismail MA
- KMID: 2353584
- Korean J Parasitol.
- 2016 Aug;54(4):527-532.
- doi: 10.3347/kjp.2016.54.4.527
Head lice, Pediculus humanus capitis, infestation is an important public health problem in Egypt. Inadequate application of topical pediculicides and the increasing resistance to the commonly used pediculicides made the... -
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- Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats
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Choi YJ, Kim N, Lee JY, Nam RH, Seo JH, Lee S, Kim HJ, Choi YJ, Lee HS, Lee DH
- KMID: 2411960
- Gut Liver.
- 2016 May;10(3):348-355.
- doi: 10.5009/gnl14509
BACKGROUND/AIMS: This study aimed to examine the gastroprotective effects of PMK-S005, which is a synthetic S-allyl-L-cysteine (SAC; a sulfur-containing amino acid), against acute ethanol-induced gastric damage in rats. METHODS: Sprague-Dawley rats... -
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- Synergistic Anti-bacterial Effects of Phellinus baumii Ethyl Acetate Extracts and beta-Lactam Antimicrobial Agents Against Methicillin-Resistant Staphylococcus aureus
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Hong SB, Rhee MH, Yun BS, Lim YH, Song HG, Shin KS
- KMID: 2373509
- Ann Lab Med.
- 2016 Mar;36(2):111-116.
- doi: 10.3343/alm.2016.36.2.111
BACKGROUND: The development of new drugs or alternative therapies effective against methicillin-resistant Staphylococcus aureus (MRSA) is of great importance, and various natural anti-MRSA products are good candidates for combination therapies.... -
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- In Vitro Scolicidal Effects of Salvadora persica Root Extract against Protoscolices of Echinococcus granulosus
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Abdel-Baki AAS, Almalki E, Mansour L, Al-Quarishy S
- KMID: 2374018
- Korean J Parasitol.
- 2016 Feb;54(1):61-66.
- doi: 10.3347/kjp.2016.54.1.61
It has been known that Arak, Salvadora persica, has a number of medicinal properties. We tried to investigate in vitro scolicidal effect of root extracts of this plant against protoscolices... -
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- Antiangiogenic Activity of Acer tegmentosum Maxim Water Extract in Vitro and in Vivo
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Kim EC, Kim SH, Piao SJ, Kim TJ, Bae K, Kim HS, Hong SS, Lee BI, Nam M
- KMID: 2164486
- J Korean Med Sci.
- 2015 Jul;30(7):979-987.
- doi: 10.3346/jkms.2015.30.7.979
Angiogenesis, the formation of new blood vessels, is critical for tumor growth and metastasis. Notably, tumors themselves can lead to angiogenesis by inducing vascular endothelial growth factor (VEGF), which is... -
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- The Effects of Broccoli Sprout Extract Containing Sulforaphane on Lipid Peroxidation and Helicobacter pylori Infection in the Gastric Mucosa
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Chang YW, Jang JY, Kim YH, Kim JW, Shim JJ
- KMID: 2160632
- Gut Liver.
- 2015 Jul;9(4):486-493.
- doi: 10.5009/gnl14040
BACKGROUND/AIMS: The aims of this study were to investigate whether a broccoli sprout extract containing sulforaphane (BSES) inhibited the Helicobacter pylori infection density and exerted an antioxidative effect on gastric... -
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