- Egg phospholipids exert an inhibitory effect on intestinal cholesterol absorption in mice
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Lee Y, Han CY, Bae M, Park YK, Lee JY
- KMID: 2453107
- Nutr Res Pract.
- 2019 Aug;13(4):295-301.
- doi: 10.4162/nrp.2019.13.4.295
BACKGROUND/OBJECTIVES: Consumption of cholesterol-rich foods, such as eggs, has a minimal effect on circulating cholesterol levels in healthy humans. To gain insight, we investigated whether phospholipids rich in eggs (EPL)... -
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- Lipidomic analysis of plasma lipids composition changes in septic mice
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Ahn WG, Jung JS, Song DK
- KMID: 2414264
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):399-408.
- doi: 10.4196/kjpp.2018.22.4.399
A lipidomic study on extensive plasma lipids in bacterial peritonitis (cecal ligation and puncture, CLP)-induced sepsis in mice was done at 24 h post-CLP. The effects of administration of lysophosphatidylcholine... -
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- Prurigo Pigmentosa after Injection Lypolysis with Phosphatidylcholine and Deoxycholate
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Yang JY, Kim SK
- KMID: 2353449
- Korean J Dermatol.
- 2016 Sep;54(8):673-674.
No abstract available. -
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- Hair Growth Promoting Potential of Phospholipids Purified from Porcine Lung Tissues
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Choi SH, Moon JS, Jeon BS, Jeon YJ, Yoon BI, Lim CJ
- KMID: 2380351
- Biomol Ther.
- 2015 Mar;23(2):174-179.
- doi: 10.4062/biomolther.2014.108
BP201, porcine lung tissue-derived phospholipids, consists of phosphatidylcholine as a major phospholipid species. BP201 promoted hair growth after application onto the shaved backs of BALB/c and C3H mice. Its effect... -
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- Stimulated Bronchial Epithelial Cells Release Bioactive Lysophosphatidylcholine 16:0, 18:0, and 18:1
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Zhuge Y, Yuan Y, van Breemen R, DeGrand M, Holian O, Yoder M, Lum H
- KMID: 2166940
- Allergy Asthma Immunol Res.
- 2014 Jan;6(1):66-74.
- doi: 10.4168/aair.2014.6.1.66
PURPOSE: In human subjects and animal models with acute and chronic lung injury, the bioactive lysophosphatidylcholine (LPC) is elevated in lung lining fluids. The increased LPC can promote an inflammatory... -
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- Bioactive Lysophosphatidylcholine 16:0 and 18:0 Are Elevated in Lungs of Asthmatic Subjects
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Yoder M, Zhuge Y, Yuan Y, Holian O, Kuo S, van Breemen R, Thomas LL, Lum H
- KMID: 2166937
- Allergy Asthma Immunol Res.
- 2014 Jan;6(1):61-65.
- doi: 10.4168/aair.2014.6.1.61
PURPOSE: Asthma is a chronic inflammatory disease of the airways, and is associated with upregulation of phospholipase A2 (PLA2), the enzyme that hydrolyzes phosphatidylcholine, producing lysophosphatidylcholine (LPC) and free fatty... -
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- Development of SCAR Markers for the Identification of Phytophthora katsurae Causing Chestnut Ink Disease in Korea
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Lee DH, Lee SK, Lee SY, Lee JK
- KMID: 2312693
- Mycobiology.
- 2013 Jun;41(2):86-93.
Sequence characterized amplified region (SCAR) markers are one of the most effective and accurate tools for microbial identification. In this study, we applied SCAR markers for the rapid and accurate... -
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- Protective Effect of Phosphatidylcholine on Lipopolysaccharide-Induced Acute Inflammation in Multiple Organ Injury
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Jung YY, Nam Y, Park YS, Lee HS, Hong SA, Kim BK, Park ES, Chung YH, Jeong JH
- KMID: 1429300
- Korean J Physiol Pharmacol.
- 2013 Jun;17(3):209-216.
- doi: 10.4196/kjpp.2013.17.3.209
Soybean polyunsaturated phosphatidylcholine (PC) is thought to exert anti-inflammatory activities and has potent effects in attenuating acute renal failure and liver dysfunction. The aim of this study was to investigate... -
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- Impact of Micellar Vehicles on in situ Intestinal Absorption Properties of Beta-Lapachone in Rats
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Jang SB, Kim D, Kim SY, Park C, Jeong JH, Kuh HJ, Lee J
- KMID: 1432757
- Korean J Physiol Pharmacol.
- 2013 Feb;17(1):9-13.
- doi: 10.4196/kjpp.2013.17.1.9
The aim of the present study was to examine the effect of micellar systems on the absorption of beta-lapachone (b-lap) through different intestinal segments using a single-pass rat intestinal perfusion... -
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- Advent of Novel Phosphatidylcholine-Associated Nonsteroidal Anti-Inflammatory Drugs with Improved Gastrointestinal Safety
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Lim YJ, Dial EJ, Lichtenberger LM
- KMID: 2053509
- Gut Liver.
- 2013 Jan;7(1):7-15.
The mucosa of the gastrointestinal (GI) tract exhibits hydrophobic, nonwettable properties that protect the underlying epithelium from gastric acid and other luminal toxins. These biophysical characteristics appear to be attributable... -
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- Multiple Signaling Molecules are Involved in Expression of CCL2 and IL-1beta in Response to FSL-1, a Toll-Like Receptor 6 Agonist, in Macrophages
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Won K, Kim SM, Lee SA, Rhim BY, Eo SK, Kim K
- KMID: 2285454
- Korean J Physiol Pharmacol.
- 2012 Dec;16(6):447-453.
- doi: 10.4196/kjpp.2012.16.6.447
TLR6 forms a heterodimer with TLR2 and TLR4. While proinflammatory roles of TLR2 and TLR4 are well documented, the role of TLR6 in inflammation is poorly understood. In order to... -
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- The Effect of Phosphatidylcholine and Deoxycholate Compound Injections to the Localized Adipose Tissue: An Experimental Study with a Murine Model
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Noh Y, Heo CY
- KMID: 2267706
- Arch Plast Surg.
- 2012 Sep;39(5):452-456.
- doi: 10.5999/aps.2012.39.5.452
BACKGROUND: Phosphatidylcholine (PPC) and deoxycholate (DCA) compound has been recently used for the purpose of partial lipolysis and is valued for its efficacy and lower invasiveness compared to liposuction and... -
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- Ingestion Exposure to Nitrosamines in Chlorinated Drinking Water
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Kim H, Han K
- KMID: 2380153
- Environ Health Toxicol.
- 2011 ;26(1):e2011003.
OBJECTIVES: N-Nitrosodimethylamine (NDMA) is classified as a probable human carcinogen by the United States Environmental Protection Agency (US EPA) and is formed during the chlorination of municipal drinking water. In... -
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- Comparative Analysis about the Effect of Isolated Phosphatidylcholine and Sodium Deoxycholate for the Viability of Adipocyte
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Rha EY, Kang JA, Lee JH, Oh DY, Seo JW, Moon SH, Ahn ST, Rhie JW
- KMID: 2322268
- J Korean Soc Plast Reconstr Surg.
- 2010 Sep;37(5):531-534.
PURPOSE: Lipobean(R)s, widely used in lipodissolving techniques, contain phosphatidylcholine and sodium deoxycholate as its main substances. They have been approved only as medication for liver disease by the FDA. However,... -
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- Phosphatidylcholine Formula for the Treatment of Lipoma
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Kim JH, Kim JB, Park HJ, Lee JS, Joh OJ, Kim HJ, Son HC, Song KY
- KMID: 2301846
- Korean J Dermatol.
- 2010 Aug;48(8):672-677.
BACKGROUND: Lipomas are benign neoplasms composed of mature fat cells. Current treatments are invasive and carry the risk of scarring. For this reason, phosphatidylcholine (PPC) formula has been widely used... -
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- Morinda citrifolia Inhibits Both Cytosolic Ca2+-dependent Phospholipase A2 and Secretory Ca2+-dependent Phospholipase A2
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Song HS, Park SH, Ko MS, Jeong JM, Sohn UD, Sim SS
- KMID: 2285398
- Korean J Physiol Pharmacol.
- 2010 Jun;14(3):163-167.
- doi: 10.4196/kjpp.2010.14.3.163
This study investigated the effects of the methanol extracts of Morinda citrifolia containing numerous anthraquinone and iridoid on phospholipase A2 (PLA2) isozyme. PLA2 activity was measured using various PLA2 substrates,... -
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- Mechanisms of Selective Antimicrobial Activity of Gaegurin 4
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Kim H, Lee BJ, Lee MH, Hong SG, Ryu PD
- KMID: 2285370
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):39-47.
- doi: 10.4196/kjpp.2009.13.1.39
Gaegurin 4 (GGN4), an antimicrobial peptide isolated from a Korean frog, is five times more potent against Gram-positive than Gram-negative bacteria, but has little hemolytic activity. To understand the mechanism... -
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- Detection of SNP of Phospholipase D1 in Children with Atopic Dermatitis
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Shin SA, Park SY, Cho JW, Han JS, Oh JW, Lee HB
- KMID: 2314507
- Pediatr Allergy Respir Dis.
- 2007 Sep;17(3):173-182.
BACKGROUND: Phospholipase D (PLD) is a widely distributed enzyme that hydrolyzes phosphatidylcholine, a major phospholipids in the cell membrane, to form phosphatidic acid (PA) which acts by itself as a... -
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- Effect of Dexamethasone on Gene Expression of Surfactant Protein B and Surfactant Protein C
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Park IS, Sohn JW, Yoon HJ, Shin DH, Park SS
- KMID: 2318416
- Tuberc Respir Dis.
- 2003 Apr;54(4):439-448.
BACKGROUND: Surfactant protein B(SP-B) and surfactant protein C(SP-C) are important in accelerating surface spreading of surfactant phospholipid. The glucocorticoids accelerate the morphologic differentiation of epithelial cells into type II cells... -
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- Effect of TRH on Phospholipase D Activity in GH3 Cell
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Kim DS, Lee CB, Ahn YH, Kim TW, Yoon MS, Han JS
- KMID: 2199978
- J Korean Soc Endocrinol.
- 2002 Aug;17(4):465-472.
BACKGROUND: GH3 cells are a well characterized and widely used model used for the in vitro study of growth hormone (GH) secretion. Thyrotropin releasing hormone (TRH) binds to receptors ... -
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