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Inhaled Iloprost as a First-Line Therapy for Persistent Pulmonary Hypertension of the Newborn

Kim SH, Lee HJ, Kim NS, Park HK

PURPOSE: Persistent pulmonary hypertension of the newborn (PPHN) is a potentially fatal disease. Inhaled iloprost, a stable analogue of prostacyclin, has recently been used as a therapeutic option. However, there...
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Tracheal Bronchus with Persistent Pulmonary Hypertension of the Newborn: A Case Report

An SH, Yi MJ, Yu R, Kim JH, Baek HS, Ban JE, Lim KJ, Yang S, Hwang IT, Kim SY

Tracheal bronchus is an uncommon anomaly in which an ectopic bronchus originates directly from the supracarinal trachea. It is usually an asymptomatic anatomical variant incidentally found on computed tomography or...
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A Novel De Novo Pathogenic Variant in FOXF1 in a Newborn with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins

Ma Y, Jang MA, Yoo HS, Ahn SY, Sung SI, Chang YS, Ki CS, Park WS

Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is an autosomal dominant, fatal developmental disorder of the lungs, with a mortality rate of about 100%. ACD/MPV is caused by...
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Lung Ultrasonography for the Diagnosis of Respiratory Distress Syndrome in Late Preterm Infants: Changing Incidence – A Single Center Experience

Sin SY, Jin MJ, Lee NH, Park JH, Kim CS, Lee SL

PURPOSE: Ultrasonography is non-ionizing, easy to operate, and performed at bedside in neonatal intensive care unit (NICU). We investigated the incidence of respiratory distress syndrome (RDS) with or without using...
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The Association between Admission Hypothermia and Neonatal Outcomes in Very Low Birth Weight Infants

Jang JH, Shin SH, Woo HK, Choi EK, Song IG, Shin SH, Kim EK, Kim HS

PURPOSE: We aimed to evaluate the effect of admission hypothermia on neonatal outcomes in very low birth weight infants (VLBWIs). METHODS: Medical records of 153 preterm infants, with birth weights
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Ruptured Tricuspid Valve Papillary Muscle in a Neonate with Intractable Persistent Fetal Circulation

Yoon JK, Kim HR, Kwon HW, Kwon BS, Kim GB, Bae EJ, Noh CI, Kim WH

Unguarded tricuspid regurgitation (TR) due to a flail tricuspid leaflet is a rare condition of newborn cyanosis. A high perinatal mortality has been associated with this fatal condition. But, there...
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Prognosis and Side Effects of Inhaled Nitric Oxide Treatment in Persistent Pulmonary Hypertension of the Newborn

Ahn SY

Inhaled nitric oxide (iNO) is a potent and selective pulmonary vasodilator agent that improves arterial oxygenation and subsequent clinical outcomes for newborn infants with persistent pulmonary hypertension of the newborn...
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Clinical Application of Inhaled Nitric Oxide Therapy in Persistent Pulmonary Hypertension of the Newborn

Lee EH, Choi BM

Inhaled nitric oxide (iNO) is recognized as a potent and selective pulmonary vasodilator that does not decrease systemic vascular tone. The therapeutic application of iNO in human was first described...
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Clinical Indications for Inhaled Nitric Oxide Therapy in Neonates

Sung TJ

Nitric oxide (NO) is a colorless, odorless gas that acts as a potent pulmonary vasodilator. When administered via inhalation, NO rapidly diffuses across the alveolarcapillary membrane and binds to hemoglobin,...
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A case of persistent pulmonary hypertension of the newborn: Treatment with inhaled iloprost

Jang YY, Park HJ

We report a case of a full-term neonate with persistent pulmonary hypertension who developed asphyxia after birth and was treated with iloprost. The neonate had persistent hypoxia and did not...
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Factors Affecting the Response to Inhaled Nitric Oxide Therapy in Persistent Pulmonary Hypertension of the Newborn Infants

Hwang SJ, Lee KH, Hwang JH, Choi CW, Shim JW, Chang YS, Park WS

Persistent pulmonary hypertension of the newborn infant (PPHN), is a clinical syndrome characterized by elevated pulmonary vascular resistance, resulting from reactive vasoconstriction or structural remodeling of the pulmonary vasculature. Although...
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Clinical response to inhaled nitric oxide in persistent pulmonary hypertension of the newborn

Ko SY, Chang YS, Park WS

We observed clinical response to inhaled nitric oxide (iNO) in 12 neonates with persistent pulmonary hypertension of the newborn (PPHN). Clinical response was defined as a decrease in oxygenation...
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Two Cases of Nitric Oxide Inhalation for Treatment of Severe Pulmonary Hypertension after Surgical Repair of Congenital Diaphragmatic Hernia

Chang YS, Kang IS, Park WS, Lee SK, Kim HH, Lee HJ

  • KMID: 2208179
  • J Korean Pediatr Soc.
  • 1996 Nov;39(11):1611-1619.
Nitric oxide, an endothelium-derived relaxing factor, is a selective pulmonary vasodilator. We have built and settled down the delivery system of nitirc oxide gas inhalation for the first time in...
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Evaluation of Tricuspid Regurgitation in Newborn Infants by Two-dimensional and Color Doppler Echocardiography

Hong YM

Two-dimensional and color doppler echocardiography were performed on 54 newborn infants (20:full-term, 21:premature, 13:asphyxated) three times to estimate tricuspid regurgitation and pulmonary artery flow. The results were as follows : 1)...
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A Case of Persistent Fetal Circulation

Lee JK, Lee C, Namgung R, Lee SK, Han DG

  • KMID: 1682544
  • J Korean Pediatr Soc.
  • 1988 Feb;31(2):234-240.
No abstract available.
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