- Human platelet lysate efficiency, stability, and optimal heparin concentration required in culture of mammalian cells
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Mohamed HE, Asker ME, Kotb NS, El Habab A
- KMID: 2472006
- Blood Res.
- 2020 Mar;55(1):35-43.
- doi: 10.5045/br.2020.55.1.35
BACKGROUND: Fetal bovine serum (FBS) has been used to support the growth and proliferation of mammalian cells for decades. Owing to several risk factors associated with FBS, several trials have... -
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- Proteomic Classification and Identification of Proteins Related to Tissue Healing of Platelet-Rich Plasma
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Lee HW, Choi KH, Kim JY, Kim KO, Haotian B, Yuxuan L, Noh KC
- KMID: 2470060
- Clin Orthop Surg.
- 2020 Mar;12(1):120-129.
- doi: 10.4055/cios.2020.12.1.120
BACKGROUND: Platelet-rich plasma (PRP) is a plasma component of autologous blood containing a high concentration of platelets. PRP is used to promote healing of damaged tissues. However, there are not... -
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- Clinical Usefulness of ¹â¸F-FC119S Positron-Emission Tomography as an Auxiliary Diagnostic Method for Dementia: An Open-Label, Single-Dose, Evaluator-Blind Clinical Trial
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Lee I, Na HR, Byun BH, Lim I, Kim BI, Choi CW, Ko IO, Lee KC, Kim KM, Park SY, Kim YK, Lee JY, Bu SH, Kim JH, Kil HS, Park C, Chi DY, Ha JH, Lim SM
- KMID: 2467795
- J Clin Neurol.
- 2020 Jan;16(1):131-139.
- doi: 10.3988/jcn.2020.16.1.131
BACKGROUND AND PURPOSE: The aim of this study was to determine the diagnostic performance and safety of a new ¹â¸F-labeled amyloid tracer, ¹â¸F-FC119S. METHODS: This study prospectively recruited 105 participants, comprising... -
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- Therapeutic Angiogenesis with Somatic Stem Cell Transplantation
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Murohara T
- KMID: 2465659
- Korean Circ J.
- 2020 Jan;50(1):12-21.
- doi: 10.4070/kcj.2019.0288
Therapeutic angiogenesis is an important strategy to rescue ischemic tissues in patients with critical limb ischemia having no other treatment option such as endovascular angioplasty or bypass surgery. Studies indicated... -
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- A Validation Study of a Multiple Reaction Monitoring-Based Proteomic Assay to Diagnose Breast Cancer
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Kim Y, Kang UB, Kim S, Lee HB, Moon HG, Han W, Noh DY
- KMID: 2470894
- J Breast Cancer.
- 2019 Dec;22(4):579-586.
- doi: 10.4048/jbc.2019.22.e57
PURPOSE: Currently, the standard screening tool for breast cancer is screening mammography. There have been many efforts to develop a blood-based diagnostic assay for breast cancer diagnosis; however, none have... -
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- A Case of Surgical Treatment of Intractable Vocal Fold Scar Using Basic Fibroblast Growth Factor and Collagen Scaffold
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Kang HT, Kim HJ, Park KN, Lee SW
- KMID: 2470496
- J Korean Soc Laryngol Phoniatr Logoped.
- 2019 Dec;30(2):124-127.
- doi: 10.22469/jkslp.2019.30.2.124
Vocal fold scarring is an intractable phonosurgical condition. The number of patients with vocal fold scars is increasing with the aging of society and with the increasing application of laryngeal... -
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- Aralia cordata Extract Activates NF-κB and MAPK Signaling Pathways and Induces Pro-inflammatory Changes in RAW264.7 Macrophages
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Seo DW, Cho YI, Yi YJ, Lee SM
- KMID: 2468022
- J Bacteriol Virol.
- 2019 Dec;49(4):153-161.
- doi: 10.4167/jbv.2019.49.4.153
Macrophages play essential roles in innate immune responses by producing various immune mediators. Therefore, modulating macrophage function is an attractive strategy to treat immune disorders. Aralia cordata var. continentalis (AC),... -
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- Wound Healing Potential of Low Temperature Plasma in Human Primary Epidermal Keratinocytes
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Cui HS, Cho YS, Joo SY, Mun CH, Seo CH, Kim JB
- KMID: 2467051
- Tissue Eng Regen Med.
- 2019 Dec;16(6):585-593.
- doi: 10.1007/s13770-019-00215-w
BACKGROUND: Low temperature plasma (LTP) was recently shown to be potentially useful for biomedical applications such as bleeding cessation, cancer treatment, and wound healing, among others. Keratinocytes are a major... -
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- Platelet-rich fibrin along with a modified minimally invasive surgical technique for the treatment of intrabony defects: a randomized clinical trial
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Ahmad N, Tewari S, Narula SC, Sharma RK, Tanwar N
- KMID: 2465380
- J Periodontal Implant Sci.
- 2019 Dec;49(6):355-365.
- doi: 10.5051/jpis.2019.49.6.355
PURPOSE: The modified minimally invasive surgical technique (M-MIST) has been successfully employed to achieve periodontal regeneration. Platelet-rich fibrin (PRF) is known to enhance wound healing through the release of growth... -
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- Study of the cartilage matrix production-promoting effect of chicken leg extract and identification of the active ingredient
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Yamada H, Nakamura U, Nakamura T, Uchida Y, Yamatsu A, Kim M
- KMID: 2464127
- Nutr Res Pract.
- 2019 Dec;13(6):480-487.
- doi: 10.4162/nrp.2019.13.6.480
BACKGROUND/OBJECTIVES: Osteoarthritis (OA) is a major public health issue in Japan and other countries, and foods that prevent or treat OA are in strong demand. Proteins and peptides in chicken... -
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- Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists
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Park JY, Chae S, Kim CS, Kim YJ, Yi HJ, Han E, Joo Y, Hong S, Yun JW, Kim H, Shin KH
- KMID: 2461036
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):427-448.
- doi: 10.4196/kjpp.2019.23.6.427
Nociceptin/orphanin FQ (N/OFQ) and its receptor, nociceptin opioid peptide (NOP) receptor, are localized in brain areas implicated in depression including the amygdala, bed nucleus of the stria terminalis, habenula, and... -
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- LGR5 and Downstream Intracellular Signaling Proteins Play Critical Roles in the Cell Proliferation of Neuroblastoma, Meningioma and Pituitary Adenoma
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Hwang M, Han MH, Park HH, Choi H, Lee KY, Lee YJ, Kim JM, Cheong JH, Ryu JI, Min KW, Oh YH, Ko Y, Koh SH
- KMID: 2463717
- Exp Neurobiol.
- 2019 Oct;28(5):628-641.
- doi: 10.5607/en.2019.28.5.628
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) has been reported to play critical roles in the proliferation of various cancer cells. However, the roles of LGR5 in brain tumors and... -
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- Reduction in post extraction waiting period for dental implant patients using plasma rich in growth factors: an in vivo study using cone-beam computed tomography
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Arya V, Malhotra V, Rao JD, Kirti S, Malhotra S, Sharma RS
- KMID: 2461481
- J Korean Assoc Oral Maxillofac Surg.
- 2019 Oct;45(5):285-293.
- doi: 10.5125/jkaoms.2019.45.5.285
OBJECTIVES: This study examined the effects of plasma-rich growth factors (PRGF) on accelerating bone regeneration/repair in fresh extraction sockets, and determined the quality and quantity of bone by assessing the... -
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- Intranasal Administration of Oxytocin Attenuates Stress Responses Following Chronic Complicated Stress in Rats
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Yang Y, Yu H, Babygirija R, Shi B, Sun W, Zheng X, Zheng J
- KMID: 2460490
- J Neurogastroenterol Motil.
- 2019 Oct;25(4):611-622.
- doi: 10.5056/jnm19065
BACKGROUND/AIMS: Gastrointestinal (GI) symptoms may develop when we fail to adapt to various stressors of our daily life. Central oxytocin (OXT) can counteract the biological actions of corticotropin-releasing factor (CRF),... -
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- Melandrium firmum Extract Promotes Hair Growth by Modulating 5α-Reductase Activity and Gene Expression in C57BL/6J Mice
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Huang B, Kang BG, Lim SS, Zhang XH
- KMID: 2456226
- Ann Dermatol.
- 2019 Oct;31(5):502-510.
- doi: 10.5021/ad.2019.31.5.502
BACKGROUND: In our preliminary study, we screened for their potential to inhibit 5α-reductase, and Melandrium firmum (MF) extract showed the most potent activity as confirmed by high-performance liquid chromatography (HPLC). OBJECTIVE:... -
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- Identification of neoantigens derived from alternative splicing and RNA modification
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Park J, Chung YJ
- KMID: 2462037
- Genomics Inform.
- 2019 Sep;17(3):e23.
- doi: 10.5808/GI.2019.17.3.e23
The acquisition of somatic mutations is the most common event in cancer. Neoantigens expressed from genes with mutations acquired during carcinogenesis can be tumor-specific. Since the immune system recognizes tumor-specific... -
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- Gadoxetic acid-enhanced magnetic resonance imaging: Hepatocellular carcinoma and mimickers
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Kim YY, Park MS, Aljoqiman , Choi JY, Kim MJ
- KMID: 2459784
- Clin Mol Hepatol.
- 2019 Sep;25(3):223-233.
- doi: 10.3350/cmh.2018.0107
Gadoxetic acid, a hepatocyte-specific magnetic resonance imaging (MRI) contrast agent, has emerged as an important tool for hepatocellular carcinoma (HCC) diagnosis. Gadoxetic acid-enhanced MRI is useful for the evaluation of... -
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- Short-term Haze Exposure Predisposes Healthy Volunteers to Nasal Inflammation
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Xian M, Wang K, Lou H, Wang Y, Zhang L, Wang C
- KMID: 2452754
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):632-643.
- doi: 10.4168/aair.2019.11.5.632
PURPOSE: This study aimed to investigate the impact of short-term haze exposure on nasal inflammation in healthy volunteers. METHODS: Thirty-three healthy university students were assessed for nasal symptoms, nasal patency, upper... -
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- Interactions Between Atopic Dermatitis and Staphylococcus aureus Infection: Clinical Implications
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Kim J, Kim BE, Ahn K, Leung DY
- KMID: 2452751
- Allergy Asthma Immunol Res.
- 2019 Sep;11(5):593-603.
- doi: 10.4168/aair.2019.11.5.593
Staphylococcus aureus commonly colonizes the skin of atopic dermatitis (AD) patients and contributes to the development and exacerbation of AD. Multiple factors are associated with colonization of AD skin by... -
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- Mechanical and Mechanosensing Properties of Tumor Affected Bone Cells Were Inhibited via PI3K/Akt Pathway
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Lee T
- KMID: 2457437
- J Bone Metab.
- 2019 Aug;26(3):179-191.
- doi: 10.11005/jbm.2019.26.3.179
BACKGROUND: Osteolytic metastasis is a common destructive form of metastasis, in which there is an increased bone resorption but impaired bone formation. It is hypothesized that the changed mechanical properties... -
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